Compile Data Set for Download or QSAR
Report error Found 120 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 6'
LigandChemical structure of BindingDB Monomer ID 50459973BDBM50459973(Sor-c13)
Affinity DataIC50: 14nMAssay Description:Inhibition of TRPV6 (unknown origin) expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50502759BDBM50502759(CHEMBL4435596)
Affinity DataIC50: 50nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50550080BDBM50550080(CHEMBL4796516)
Affinity DataIC50: 64nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50550078BDBM50550078(CHEMBL4777551)
Affinity DataIC50: 82nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50550077BDBM50550077(CHEMBL4789936)
Affinity DataIC50: 130nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50634811BDBM50634811(CHEMBL5518142)
Affinity DataIC50: 130nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50550081BDBM50550081(CHEMBL4740003)
Affinity DataIC50: 150nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50550082BDBM50550082(CHEMBL4760109)
Affinity DataIC50: 170nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50634815BDBM50634815(CHEMBL5542781)
Affinity DataIC50: 190nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50634816BDBM50634816(CHEMBL5543003)
Affinity DataIC50: 310nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50502759BDBM50502759(CHEMBL4435596)
Affinity DataIC50: 320nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition by calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50550085BDBM50550085(CHEMBL4762249)
Affinity DataIC50: 370nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50550087BDBM50550087(CHEMBL4761058)
Affinity DataIC50: 430nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50634791BDBM50634791(CHEMBL5556793)
Affinity DataIC50: 440nMAssay Description:Inhibition of TRPV6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50550083BDBM50550083(CHEMBL4746237)
Affinity DataIC50: 550nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50502760BDBM50502760(CHEMBL4475503)
Affinity DataIC50: 550nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50634812BDBM50634812(CHEMBL5557326)
Affinity DataIC50: 570nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50502761BDBM50502761(CHEMBL4448267)
Affinity DataIC50: 600nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50502757BDBM50502757(CHEMBL4470714)
Affinity DataIC50: 600nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx preincubated for 5 mins followed by CdCl2 addition using 365...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50550084BDBM50550084(CHEMBL4789446)
Affinity DataIC50: 600nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50550079BDBM50550079(CHEMBL4742895)
Affinity DataIC50: 690nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50634798BDBM50634798(CHEMBL5555456)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50550089BDBM50550089(CHEMBL4789968)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50502760BDBM50502760(CHEMBL4475503)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition by calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50502762BDBM50502762(CHEMBL4579017)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx preincubated for 5 mins followed by CdCl2 addition using 365...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50634800BDBM50634800(CHEMBL5517726)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50502760BDBM50502760(CHEMBL4475503)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50634802BDBM50634802(CHEMBL5559359)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50550088BDBM50550088(CHEMBL4792477)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50550090BDBM50550090(CHEMBL4749205)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50550086BDBM50550086(CHEMBL4790237)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50634813BDBM50634813(CHEMBL5532006)
Affinity DataIC50: 2.84E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50634814BDBM50634814(CHEMBL5517874)
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50634797BDBM50634797(CHEMBL5532025)
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50634801BDBM50634801(CHEMBL5512439)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50134038BDBM50134038(1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)eth...)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibition of human TRPV6 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50634803BDBM50634803(CHEMBL5557022)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50434536BDBM50434536(CHEMBL2386186)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50634805BDBM50634805(CHEMBL5555589)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50434536BDBM50434536(CHEMBL2386186)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50634804BDBM50634804(CHEMBL5559197)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50634808BDBM50634808(CHEMBL5512512)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50634817BDBM50634817(CHEMBL5542330)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of TRPV6 (unknown origin) expressed in Sf9 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50511105BDBM50511105(GWP-42004 | Gwp42004 | O-4394 | THCV | Tetrahydroc...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of TRPV6 channel (unknown origin) by Patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50634799BDBM50634799(CHEMBL5558268)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human TRPV6 (1 to 725 residues) by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50434538BDBM50434538(CHEMBL2386184)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50434537BDBM50434537(CHEMBL2386185)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50434539BDBM50434539(CHEMBL2386183)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50502758BDBM50502758(CHEMBL4580679)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50434550BDBM50434550(CHEMBL2386171)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Displayed 1 to 50 (of 120 total ) | Next | Last >>
Jump to: