Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with Target = 'Tubulin alpha chain'
LigandChemical structure of BindingDB Monomer ID 50517652BDBM50517652(CHEMBL4584084)
Affinity DataIC50: 540nMAssay Description:Inhibition of tubulin alpha in human A2780 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetTubulin alpha chain(Trypanosoma cruzi)
Howard University

US Patent
LigandChemical structure of BindingDB Monomer ID 240700BDBM240700(US9422231, IMDNQ3)
Affinity DataIC50: 3.20E+3nMpH: 6.9 T: 2°CAssay Description:Tubulin assembly assays were conducted to assess tubulin polymerization inhibition. The assays were conducted in a 96-well microplate. Assembly react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetTubulin alpha chain(Sheep)TBA
LigandChemical structure of BindingDB Monomer ID 50487731BDBM50487731(CHEMBL2262117)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to Ovis aries (sheep) brain tubulin assessed as intrinsic tryptophan fluorescence after 30 min by fluorescence spectroscopic analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTubulin alpha chain(Trypanosoma cruzi)
Howard University

US Patent
LigandChemical structure of BindingDB Monomer ID 50375664BDBM50375664(CHEMBL404939 | US9422231, IMDNQ1)
Affinity DataIC50: 6.00E+3nMpH: 6.9 T: 2°CAssay Description:Tubulin assembly assays were conducted to assess tubulin polymerization inhibition. The assays were conducted in a 96-well microplate. Assembly react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81744BDBM81744(Oryzalin Analogue, 3)
Affinity DataIC50: 6.40E+3nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81745BDBM81745(Oryzalin Analogue, 4)
Affinity DataIC50: 6.60E+3nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Trypanosoma cruzi)
Howard University

US Patent
LigandChemical structure of BindingDB Monomer ID 240703BDBM240703(US9422231, IMDNQ10)
Affinity DataIC50: 8.00E+3nMpH: 6.9 T: 2°CAssay Description:Tubulin assembly assays were conducted to assess tubulin polymerization inhibition. The assays were conducted in a 96-well microplate. Assembly react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetTubulin alpha chain(Trypanosoma cruzi)
Howard University

US Patent
LigandChemical structure of BindingDB Monomer ID 240701BDBM240701(US9422231, IMDNQ2)
Affinity DataIC50: 1.20E+4nMpH: 6.9 T: 2°CAssay Description:Tubulin assembly assays were conducted to assess tubulin polymerization inhibition. The assays were conducted in a 96-well microplate. Assembly react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81746BDBM81746(Chembridge No 7992831, 5)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Sheep)TBA
LigandChemical structure of BindingDB Monomer ID 50487731BDBM50487731(CHEMBL2262117)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 30 min by CD spectra analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTubulin alpha chain(Sheep)TBA
LigandChemical structure of BindingDB Monomer ID 50487731BDBM50487731(CHEMBL2262117)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTubulin alpha chain(Sheep)TBA
LigandChemical structure of BindingDB Monomer ID 86012BDBM86012(Chalcone, 11)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTubulin alpha chain(Sheep)TBA
LigandChemical structure of BindingDB Monomer ID 50487732BDBM50487732(CHEMBL2262305)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTubulin alpha chain(Sheep)TBA
LigandChemical structure of BindingDB Monomer ID 50067040BDBM50067040(CHEMBL116438 | 1,7-bis(4-hydroxy-3-methoxyphenyl)1...)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81743BDBM81743(Oryzalin, 1)
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Trypanosoma cruzi)
Howard University

US Patent
LigandChemical structure of BindingDB Monomer ID 240702BDBM240702(US9422231, IMDNQ11)
Affinity DataIC50: 4.00E+4nMpH: 6.9 T: 2°CAssay Description:Tubulin assembly assays were conducted to assess tubulin polymerization inhibition. The assays were conducted in a 96-well microplate. Assembly react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetTubulin alpha chain(Sheep)TBA
LigandChemical structure of BindingDB Monomer ID 86007BDBM86007(Chalcone, 6)
Affinity DataIC50: 4.93E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTubulin alpha chain(Sheep)TBA
LigandChemical structure of BindingDB Monomer ID 50487733BDBM50487733(CHEMBL2262116)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81747BDBM81747(Chembridge No 9067250, Class 1, 8)
Affinity DataIC50: 5.50E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81748BDBM81748(Chembridge No 7946770, Class 1, 9)
Affinity DataIC50: 5.80E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81753BDBM81753(Chembridge No 9035165, Class 2, 13)
Affinity DataIC50: 6.00E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81749BDBM81749(Chembridge No 7960631, Class 1, 10)
Affinity DataIC50: 6.40E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81752BDBM81752(Chembridge No 9035650, Class 2, 12)
Affinity DataIC50: 6.60E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81751BDBM81751(Chembridge No 9041709, Class 2, 11)
Affinity DataIC50: 6.80E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81750BDBM81750(Chembridge No 9063043, Class 1, 17)
Affinity DataIC50: 7.00E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81756BDBM81756(Chembridge No 9056942, Class 3, 7)
Affinity DataIC50: 7.80E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81758BDBM81758(Chembridge No 9044486, Class 4, 6)
Affinity DataIC50: 8.10E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81755BDBM81755(Chembridge No 9026860, Class 3, 14)
Affinity DataIC50: 8.90E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81754BDBM81754(Chembridge No 7944934, Class 2, 16)
Affinity DataIC50: 9.50E+4nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTubulin alpha chain(Leishmania tarentolae (Sauroleishmania tarentolae))
The Ohio State University

LigandChemical structure of BindingDB Monomer ID 81757BDBM81757(Chembridge No 9049411, Class 4, 15)
Affinity DataIC50: 1.07E+5nMAssay Description:In vitro activity assay using leishmania tarentolae and porcine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed