SMILES for Proto-oncogene tyrosine-protein kinase receptor Ret [G810R]

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC3C[C@H](O)C3)cn3ncc(C#N)c23)cn1 |r,wU:26.29,(12.54,-2.37,;11.21,-1.6,;9.87,-2.37,;8.54,-1.6,;7.21,-2.37,;7.21,-3.91,;5.87,-4.68,;4.54,-3.91,;3.21,-4.68,;3.21,-3.14,;4.54,-2.37,;3.21,-1.6,;1.87,-2.37,;1.87,-3.91,;.54,-1.6,;-.8,-2.37,;-2.13,-1.6,;-2.13,-.06,;-.8,.71,;.54,-.06,;-3.46,.71,;-4.8,-.06,;-6.13,.71,;-7.46,-.06,;-8.95,.33,;-9.72,1.67,;-11.05,.9,;-12.54,1.3,;-10.28,-.44,;-6.13,2.25,;-4.8,3.02,;-4.48,4.52,;-2.94,4.68,;-2.32,3.28,;-.83,2.88,;.66,2.48,;-3.46,2.25,;8.54,-4.68,;9.87,-3.91,)|

BDBM296725

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H]3C[C@H](O)C3)cn3ncc(C#N)c23)cn1 |r,wU:25.27,27.30,(12.95,-2.37,;11.61,-1.6,;10.28,-2.37,;8.94,-1.6,;7.61,-2.37,;7.61,-3.91,;6.28,-4.68,;4.94,-3.91,;3.61,-4.68,;3.61,-3.14,;4.94,-2.37,;3.61,-1.6,;2.28,-2.37,;2.28,-3.91,;.94,-1.6,;-.39,-2.37,;-1.72,-1.6,;-1.72,-.06,;-.39,.71,;.94,-.06,;-3.06,.71,;-4.39,-.06,;-5.72,.71,;-7.06,-.06,;-8.39,.71,;-9.73,-.06,;-11.21,.34,;-11.61,-1.15,;-12.95,-1.92,;-10.12,-1.55,;-5.72,2.25,;-4.39,3.02,;-4.07,4.52,;-2.54,4.68,;-1.91,3.28,;-.43,2.88,;1.06,2.48,;-3.06,2.25,;8.94,-4.68,;10.28,-3.91,)|

BDBM296727

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCC3CN(C)C3)cn3ncc(C#N)c23)cn1

BDBM296735

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCn3ccnc3)cn3ncc(C#N)c23)cn1

BDBM296736

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCc3cccnc3)cn3ncc(C#N)c23)cn1

BDBM296738

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](O)C(F)(F)F)cn3ncc(C#N)c23)cn1 |r|

BDBM296740

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H](C)O)cn3ncc(C#N)c23)cc1F |r|

BDBM296743

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](C)O)cn3ncc(C#N)c23)cc1F |r|

BDBM296744

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](C)O)cn3ncc(C#N)c23)cc1Cl |r|

BDBM296748

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](O)CN(C)C)cn3ncc(C#N)c23)cn1 |r|

BDBM296749

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3(O)CC3)cn3ncc(C#N)c23)cn1

BDBM296754

COc1ccc(CN2C3COCC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296769

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)c2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM296770

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM296771

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3)c2c(cnn2c1)C#N |r|

BDBM296772

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3c2ccc(OC)nc2)c2c(cnn2c1)C#N |r|

BDBM296773

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3S(=O)(=O)c3ccc(C)cc3)CC2)c2c(cnn2c1)C#N

BDBM296774

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3S(=O)(=O)c3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM296775

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3S(=O)(=O)c3ccc(F)cc3)CC2)c2c(cnn2c1)C#N

BDBM296776

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3S(=O)(=O)c3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM296777

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3S(=O)(=O)c3ccc(OC)cc3)CC2)c2c(cnn2c1)C#N

BDBM296778

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3C(=O)c3ccc(F)cc3)CC2)c2c(cnn2c1)C#N

BDBM296779

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3C(=O)c3ccc(OC)cc3)CC2)c2c(cnn2c1)C#N

BDBM296780

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3C(=O)c3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM296781

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3C(=O)c3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM296782

CCOc1cc(-c2ccc(nc2)N2CCC3(C2)CCCN(C3)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM296783

CCOc1cc(-c2ccc(nc2)N2CCC3(C2)CCCNC3)c2c(cnn2c1)C#N

BDBM296784

CCOc1cc(-c2ccc(nc2)N2CCC3(C2)CCCN(C3)c2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM296785

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(C3)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM296786

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCNC3)c2c(cnn2c1)C#N |r|

BDBM296787

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(C3)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM296788

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCNC3)c2c(cnn2c1)C#N |r|

BDBM296789

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(C3)C(C)=O)c2c(cnn2c1)C#N |r|

BDBM296790

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(C3)C(C)=O)c2c(cnn2c1)C#N |r|

BDBM296791

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(C3)C2CC2)c2c(cnn2c1)C#N |r|

BDBM296792

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(C3)C2CC2)c2c(cnn2c1)C#N |r|

BDBM296793

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(C)C3)c2c(cnn2c1)C#N |r|

BDBM296794

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(C)C3)c2c(cnn2c1)C#N |r|

BDBM296795

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(CC)C3)c2c(cnn2c1)C#N |r|

BDBM296796

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(C3)C(C)C)c2c(cnn2c1)C#N |r|

BDBM296797

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(C3)C(C)C)c2c(cnn2c1)C#N |r|

BDBM296798

CC(C)(C)OC(=O)N1CCC11CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM296799

CC(C)C(=O)N1CCC11CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM296800

COC(C)(C)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2cccc(Cl)c2)c2c(cnn2c1)C#N |r|

BDBM296801

COc1ccc(cn1)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296807

CCOc1cc(-c2cnc(cn2)N2CCN(CC2)C(=O)[C@H](O)c2cccc(Cl)c2)c2c(cnn2c1)C#N |r|

BDBM296808

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM296809

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2cnc(OC)c(F)c2)c2c(cnn2c1)C#N

BDBM296810

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2cnc(OC)c(Cl)c2)c2c(cnn2c1)C#N

BDBM296812

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(OC)c(F)c2)c2c(cnn2c1)C#N

BDBM296813

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(OC)cn2)c2c(cnn2c1)C#N

BDBM296814

COc1ncc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cc1Cl

BDBM296815

COc1ccc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cn1

BDBM296816

COc1ccc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OC[C@@H]3CNCCO3)cn3ncc(C#N)c23)cn1 |r|

BDBM296817

COc1ccc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OC[C@H]3CNCCO3)cn3ncc(C#N)c23)cn1 |r|

BDBM296818

COc1ccc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OCC3(F)CNC3)cn3ncc(C#N)c23)cn1

BDBM296819

COc1ncc(CN2C3CC2CN(C3)c2ncc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cc1Cl

BDBM296820

COc1ccc(CN2C3CC2CN(C3)c2ncc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cn1

BDBM296821

COc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(Cl)cnn2c1

BDBM296822

COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(cnn2c1)C(C)C#N

BDBM296823

COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(CC#N)cnn2c1

BDBM296824

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2cnc(OC)c(C)c2)c2c(cnn2c1)C#N

BDBM296825

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2cncc(F)c2)c2c(cnn2c1)C#N

BDBM296826

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(CC)C3)c2c(cnn2c1)C#N |r|

BDBM303321

COc1ccc(CN2CCN(CC2)c2ccc(cc2)-c2cc(OCc3cccnc3)cn3ncc(C#N)c23)cn1

BDBM303406

COc1ccc(CN2C3CC2CN(C3)c2ccc(cc2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM303768

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(CC)nc2)c2c(cnn2c1)C#N

BDBM304971

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(OC)cn2ncc(C#N)c12)C(=O)NC(C)C

BDBM304989

CCOc1cc(-c2ccc(nc2)N2CCC[C@@H](C2)N(C)C)c2c(cnn2c1)C#N |r|

BDBM304993

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305011

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305013

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N

BDBM305019

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305023

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305024

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305028

CCOc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305029

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2cnc(OC)c(F)c2)c2c(cnn2c1)C#N |r|

BDBM305031

COc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM305033

CC(C)CS(=O)(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305046

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305048

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)cc(F)c2)c2c(cnn2c1)C#N

BDBM305062

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305063

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305067

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2F)c2c(cnn2c1)C#N

BDBM305071

Cc1ncc(Cl)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305089

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c(cnn2c1)C#N

BDBM305185

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305186

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305188

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2cnccn2)c2c(cnn2c1)C#N |r|

BDBM305189

COc1ccc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM305191

COc1cccc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1 |r|

BDBM305194

COc1cncc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1 |r|

BDBM305195

COc1ncc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM305196

COc1ccc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1 |r|

BDBM305221

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N |r|

BDBM305223

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2ccccc2Cl)c2c(cnn2c1)C#N |r|

BDBM305224

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2ccccc2F)c2c(cnn2c1)C#N |r|

BDBM305225

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2cccc(F)c2)c2c(cnn2c1)C#N |r|

BDBM305226

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N

BDBM305227

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C2)NC(=O)c2cccc(F)c2F)c2c(cnn2c1)C#N

BDBM305228

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C2)NC(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM305229

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C2)NC(=O)c2ncccc2F)c2c(cnn2c1)C#N

BDBM305230

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305261

Cn1c(nc2ccccc12)C1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305262

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)c2nc3ccccc3[nH]2)c2c(cnn2c1)C#N

BDBM305266

Cc1cnc(N[C@@H]2[C@H]3C[C@@H]2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM305267

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3Nc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305268

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3Nc2ncccc2Cl)c2c(cnn2c1)C#N |r|

BDBM305269

Cc1nccc(N[C@@H]2[C@H]3C[C@@H]2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1 |r|

BDBM305270

Cc1ccc(F)c(N[C@@H]2[C@H]3C[C@@H]2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1 |r|

BDBM305285

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305286

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12

BDBM305287

CN1CC(F)(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3cc(F)ccc3C)c3c(cnn3c2)C#N)C1

BDBM305288

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305289

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCCC2)cn2ncc(C#N)c12

BDBM305290

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305292

CN1CC(C)(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3cc(F)ccc3C)c3c(cnn3c2)C#N)C1

BDBM305294

CN1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3cc(F)ccc3C)c3c(cnn3c2)C#N)CC1

BDBM305295

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OC[C@@H]2CNCCO2)cn2ncc(C#N)c12 |r|

BDBM305296

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305298

Cn1cnc(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ncccc3Cl)c3c(cnn3c2)C#N)c1

BDBM305299

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305300

CN1CC(F)(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ncccc3Cl)c3c(cnn3c2)C#N)C1

BDBM305301

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305302

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305303

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCCC2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305305

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305306

CC(=O)NCCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305307

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCNCC(F)F)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305308

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(OC)nn2)c2c(cnn2c1)C#N

BDBM305309

CCOc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305318

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)CCO)c2c(cnn2c1)C#N

BDBM305319

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)CC(C)(C)O)c2c(cnn2c1)C#N

BDBM305320

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305321

CCOc1cc(-c2ccc(nc2)N2CCC(COC)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305322

CCOc1cc(-c2ccc(nc2)N2CCC(COCC(=O)N(C)C)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305323

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(Cc3ccc(OC)cc3)CC2)c2c(cnn2c1)C#N

BDBM305324

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305325

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM305326

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305327

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2ncccc2F)c2c(cnn2c1)C#N

BDBM305328

CCOc1cc(-c2ccc(nc2)N2CCC[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305329

CCOc1cc(-c2ccc(nc2)N2CCC[C@H](C2)N(C)C)c2c(cnn2c1)C#N |r|

BDBM305342

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305343

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)Oc2ccc(OC)cn2)c2c(cnn2c1)C#N |r|

BDBM305345

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)Oc2cc(F)c(OC)cn2)c2c(cnn2c1)C#N |r|

BDBM305346

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305347

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2ccc(OC)cn2)c2c(cnn2c1)C#N |r|

BDBM305352

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305353

CCOc1cc(-c2ccc(nc2)N2CCC(CC)(CC2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305355

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)S(=O)(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305356

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(C)=O)c2c(cnn2c1)C#N

BDBM305358

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)Cc2ccccc2)c2c(cnn2c1)C#N

BDBM305359

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305360

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3N)c2c(cnn2c1)C#N |r|

BDBM305361

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3Nc2nc(C)ccc2F)c2c(cnn2c1)C#N |r|

BDBM305362

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305363

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CCCO)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305366

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305367

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305368

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305369

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305370

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305371

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305372

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305373

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2ncccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305374

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2cc(F)ccc2F)c2c(cnn2c1)C#N

BDBM305375

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)OC)c2c(cnn2c1)C#N

BDBM305376

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305377

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305378

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305379

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305380

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305381

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305382

CN1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(CC3)Oc3ccccn3)c3c(cnn3c2)C#N)CC1

BDBM305383

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305384

N#Cc1cnn2cc(OCCN3CCOCC3)cc(-c3ccc(nc3)N3CCC(CC3)Oc3ccccn3)c12

BDBM305385

CN1CC(CCOc2cc(-c3ccc(nc3)N3CCC(CC3)Oc3ccccn3)c3c(cnn3c2)C#N)C1

BDBM305386

CN1CCOC(COc2cc(-c3ccc(nc3)N3CCC(CC3)Oc3ccccn3)c3c(cnn3c2)C#N)C1

BDBM305387

N#Cc1cnn2cc(OCCN3CCCC3)cc(-c3ccc(nc3)N3CCC(CC3)Oc3ccccn3)c12

BDBM305389

NC(=O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305390

CNC(=O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305396

N#Cc1cnn2cc(OCCN3CCOCC3)cc(-c3ccc(nc3)N3CC(C3)Oc3ccccn3)c12

BDBM305397

COCCOc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305400

COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(C)nn2)c2c(Cl)cnn2c1

BDBM305404

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(Cl)cnn2c1

BDBM305405

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c(F)cccc2Cl)c2c(Cl)cnn2c1

BDBM305406

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c(Cl)cnn2c1

BDBM305407

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C1CC1

BDBM305408

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2ccc(OC)nc2)c2c(Cl)cnn2c1 |r|

BDBM305410

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(Cl)cnn2c1

BDBM305412

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@H](C2)Oc2ccccn2)c2c(Cl)cnn2c1 |r|

BDBM305414

COc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(Cl)c23)cn1

BDBM305415

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCCN2CCCC2)cn2ncc(C#N)c12)NC(=O)c1ncc(F)cc1Cl

BDBM305416

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ncc(F)cc1Cl

BDBM305417

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305418

COCCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305419

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305420

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ccccc1

BDBM305421

Cn1cnc(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccc3)c3c(cnn3c2)C#N)c1

BDBM305422

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCCC2)cn2ncc(C#N)c12)NC(=O)c1ccccc1

BDBM305424

CN1CC(F)(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccc3)c3c(cnn3c2)C#N)C1

BDBM305425

CN1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccc3)c3c(cnn3c2)C#N)CC1

BDBM305426

CCN1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccc3)c3c(cnn3c2)C#N)CC1

BDBM305428

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N

BDBM305429

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305433

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305434

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305435

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305436

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305437

Cn1cnc(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccn3)c3c(cnn3c2)C#N)c1

BDBM305438

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305439

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCn2ccnc2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305440

Cn1ccnc1COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305441

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCCC2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305442

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCC2CNC2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305443

CN1CC(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccn3)c3c(cnn3c2)C#N)C1

BDBM305444

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305445

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305446

CN1CC(F)(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccn3)c3c(cnn3c2)C#N)C1

BDBM305447

CC(=O)N1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccn3)c3c(cnn3c2)C#N)CC1

BDBM305448

CN1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccn3)c3c(cnn3c2)C#N)CC1

BDBM305456

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccccn2)c2c(cnn2c1)C#N

BDBM305463

CCOc1cc(-c2ccc(nc2)N2CCC(O)CC2)c2c(cnn2c1)C#N

BDBM305465

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305470

CC1(CCN(CC1)c1ccc(cn1)-c1cc(O)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305472

COc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305473

CO[C@@H]1CN(CC[C@H]1NC(=O)OC(C)(C)C)c1ccc(cn1)-c1cc(OC)cn2ncc(C#N)c12 |r|

BDBM305474

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305475

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305476

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(CCC3)C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305477

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(C)CCC3)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305478

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(CC3)C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305479

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C(C)C(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305480

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305481

COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(Cl)cnn2c1

BDBM305482

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)C)c2c(Cl)cnn2c1

BDBM305483

CCOc1cc(-c2ccc(nc2)N2C[C@H](O)[C@H](C2)NC(=O)CC(C)C)c2c(cnn2c1)C#N |r|

BDBM305484

CCOc1cc(-c2ccc(nc2)N2C[C@H](O)[C@@H](C2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305485

CCOc1cc(-c2ccc(nc2)N2C[C@@H](O)[C@H](C2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305486

CCOc1cc(-c2ccc(nc2)N2C[C@@H](NC(=O)CC(C)C)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305487

CCOc1cc(-c2ccc(nc2)N2C[C@@H](NC(=O)c3ccccc3)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305488

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)NC(=O)CC(C)C)c2c(cnn2c1)C#N |r|

BDBM305489

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)NC(=O)CC(C)C)c2c(cnn2c1)C#N |r|

BDBM305490

CCOC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM305491

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)OC(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305492

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305493

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305494

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](N)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305495

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)OC(C)(C)C)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305496

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305497

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)(C)C)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305498

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305499

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](C2)OCCN(C)C)c2c(cnn2c1)C#N |r|

BDBM305500

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)(C)C)[C@H](C2)OCCN(C)C)c2c(cnn2c1)C#N |r|

BDBM305501

CCOc1cc(-c2ccc(nc2)N2CC[C@H](N)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305502

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305503

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305504

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305505

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(CCC3)C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305506

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305507

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(C)CCC3)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305508

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(CC3)C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305509

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C(C)C(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305510

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)c3ncccc3Cl)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305511

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3Cl)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305512

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)c3ncccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305513

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)OC(C)C)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305514

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305515

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)OC(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305516

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)Nc2nc(C)ccc2F)c2c(cnn2c1)C#N

BDBM305517

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCCC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305518

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@H](CC)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305519

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305520

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305521

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305522

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@@H]2CCN2C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305523

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCOCC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305524

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCC2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM305525

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(O)CC2)c2c(cnn2c1)C#N

BDBM305526

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(C)CCC2)c2c(cnn2c1)C#N

BDBM305527

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(N)CCCC2)c2c(cnn2c1)C#N

BDBM305528

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCOCC2)N(C)C)c2c(cnn2c1)C#N

BDBM305529

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCC2)N(C)C)c2c(cnn2c1)C#N

BDBM305530

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@@H](N)CC)c2c(cnn2c1)C#N |r|

BDBM305531

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(N)CC2)c2c(cnn2c1)C#N

BDBM305532

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@H](C)NC)c2c(cnn2c1)C#N |r|

BDBM305533

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@@H]2CCN2C)c2c(cnn2c1)C#N |r|

BDBM305534

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCCC2)N(C)C)c2c(cnn2c1)C#N

BDBM305538

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OCC2CC2)c2c(cnn2c1)C#N

BDBM305539

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC2CCCC2)c2c(cnn2c1)C#N

BDBM305540

CCOC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM305541

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OCC(C)C)c2c(cnn2c1)C#N

BDBM305542

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)O[C@H]2CCOC2)c2c(cnn2c1)C#N |r|

BDBM305543

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC2CCC2)c2c(cnn2c1)C#N

BDBM305544

CCOc1cc(-c2ccc(nc2)N2CCC(N)(COCCN3CCOCC3)CC2)c2c(cnn2c1)C#N

BDBM305545

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN3CCOCC3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305546

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN3CCOCC3)(CC2)NC(=O)c2cccc(Cl)n2)c2c(cnn2c1)C#N

BDBM305547

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN3CCOCC3)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305548

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN3CCOCC3)(CC2)NS(=O)(=O)c2ccc(C)cc2)c2c(cnn2c1)C#N

BDBM305549

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CNS(=O)(=O)c3ccc(C)cc3)CC2)c2c(cnn2c1)C#N

BDBM305550

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CNS(=O)(=O)c3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305551

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)CC2(CC2)OC)c2c(cnn2c1)C#N

BDBM305552

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)C(C)C(C)C)c2c(cnn2c1)C#N

BDBM305553

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)c2ncccc2F)c2c(cnn2c1)C#N

BDBM305554

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)c2ncccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305555

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)OCC(C)C)c2c(cnn2c1)C#N

BDBM305556

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)OCC(C)(C)C)c2c(cnn2c1)C#N

BDBM305557

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)OCC2CC2)c2c(cnn2c1)C#N

BDBM305558

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305559

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)N2CCCC2)c2c(cnn2c1)C#N

BDBM305560

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)N2CCCCC2)c2c(cnn2c1)C#N

BDBM305561

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305562

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305563

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCCC3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305564

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCCC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305565

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305566

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC)c2c(cnn2c1)C#N

BDBM305567

CCCC(=O)NC1(CN2CCOCC2)CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM305568

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(F)(F)F)c2c(cnn2c1)C#N

BDBM305569

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(C)C(F)(F)F)c2c(cnn2c1)C#N

BDBM305570

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)C(C)C(C)C)c2c(cnn2c1)C#N

BDBM305571

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(C)(C)O)c2c(cnn2c1)C#N

BDBM305572

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(C)(C)OC)c2c(cnn2c1)C#N

BDBM305573

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)C2(CC2)OC)c2c(cnn2c1)C#N

BDBM305574

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)C[C@@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305575

CCOC(=O)NC1(CN2CCOCC2)CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM305576

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305577

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)C(C)C(C)C)c2c(cnn2c1)C#N

BDBM305579

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305580

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2cc(Cl)cnc2C)c2c(cnn2c1)C#N

BDBM305581

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305582

CCOC(=O)NC1(CN2CCN(CC)CC2)CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM305583

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305584

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305585

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)[C@@H](C)C3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N |r|

BDBM305586

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)[C@@H](C)C3)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N |r|

BDBM305587

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN([C@@H](C)C3)C(=O)OC(C)(C)C)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N |r|

BDBM305588

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN[C@@H](C)C3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N |r|

BDBM305589

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)[C@@H](C)C3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N |r|

BDBM305590

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)[C@@H](C)C3)(CC2)NC(=O)Oc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305591

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC3)C(=O)OC(C)(C)C)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305592

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCNCC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305593

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)CC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305594

CCOc1cc(-c2ccc(nc2)N2CCC(CCNC3CCN(C)CC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305595

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CCOC)CC3)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305596

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CC(C)(C)O)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305597

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC(C)(O)C3)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305600

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)Cc2nccn2C)c2c(cnn2c1)C#N

BDBM305601

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CN(C)C)c2c(cnn2c1)C#N

BDBM305602

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@H]2CCCN2C)c2c(cnn2c1)C#N |r|

BDBM305603

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CN2CCCCC2)c2c(cnn2c1)C#N

BDBM305604

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)c2cncn2C)c2c(cnn2c1)C#N

BDBM305605

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@@H](C)OC)c2c(cnn2c1)C#N |r|

BDBM305606

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CN2CCOCC2)c2c(cnn2c1)C#N

BDBM305607

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)N(C)C)c2c(cnn2c1)C#N

BDBM305608

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CC2CNC2)c2c(cnn2c1)C#N

BDBM305609

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CC2CNCCO2)c2c(cnn2c1)C#N

BDBM305610

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CC2CN(CC)CCO2)c2c(cnn2c1)C#N

BDBM305611

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@@H](N)[C@@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305612

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@@H](C)N)c2c(cnn2c1)C#N |r|

BDBM305613

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CCN2CCOCC2)c2c(cnn2c1)C#N

BDBM305614

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@H](N)C(C)C)c2c(cnn2c1)C#N |r|

BDBM305615

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@@H](N)C(C)C)c2c(cnn2c1)C#N |r|

BDBM305616

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CCO)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305617

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CCN(C)C)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305618

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CC(=O)N(C)C)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305619

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C[C@@H]3C)C(=O)OC(C)(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305620

CCOc1cc(-c2ccc(nc2)N2CCC(CNC3CCOCC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305621

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC4CC(C3)N4C(=O)OC(C)(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305622

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC4(CN(C)C4)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305623

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC(C3)N(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305624

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCC(F)(F)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305625

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC(C3)OC)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305626

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CCOC)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305627

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC[C@@H](C3)OC)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305628

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC[C@H](C3)OC)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305629

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC(F)(F)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305630

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN([C@@H](C)C3)C(=O)OC(C)(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305631

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN([C@H](C)C3)C(=O)OC(C)(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305632

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C(=O)OC(C)(C)C)C(C)(C)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305633

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN[C@@H](C)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305634

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCNC[C@@H]3C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305635

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC4CC(C3)N4)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305636

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)[C@H](C)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305637

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)C(C)(C)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305638

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)[C@@H](C)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305639

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305640

CCOC(=O)C1(CO)CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM305641

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN3CCOCC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305642

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305643

CCOc1cc(-c2ccc(nc2)N2CCC3(CC(C3)NC(=O)OC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM305644

CCOc1cc(-c2ccc(cc2)N2CCC(CN(C)C)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305645

CN(C)C(=O)Oc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305646

CN(C)C(=O)Oc1cc(-c2ccc(nc2)N2CCC(C)(N)CC2)c2c(cnn2c1)C#N

BDBM305647

CC(C)OC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OC(=O)N(C)C)cn2ncc(C#N)c12

BDBM305648

CC(C)OC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCn2ccnc2)cn2ncc(C#N)c12

BDBM305649

CC(C)OC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCc2cn(C)cn2)cn2ncc(C#N)c12

BDBM305650

CC(C)OC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305651

CC(C)COC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305652

CC(C)CC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305653

CC(C)[C@H](C)NC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12 |r|

BDBM305654

CC(C)[C@@H](C)NC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12 |r|

BDBM305655

CC(C)CNC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305656

CC(C)(C)OC(=O)N1CCO[C@H](COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ncccc3Cl)c3c(cnn3c2)C#N)C1 |r|

BDBM305657

CC(C)(C)OC(=O)N1CCO[C@@H](COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ncccc3Cl)c3c(cnn3c2)C#N)C1 |r|

BDBM305658

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OC[C@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl |r|

BDBM305659

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OC[C@@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl |r|

BDBM305660

CN1CCO[C@H](COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ncccc3Cl)c3c(cnn3c2)C#N)C1 |r|

BDBM305661

CN1CCO[C@@H](COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ncccc3Cl)c3c(cnn3c2)C#N)C1 |r|

BDBM305662

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305663

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305664

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1ncc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305665

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ncc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305666

CC1(CCN(CC1)c1ncc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1cc(F)ccc1Cl

BDBM305667

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305668

CN(C)CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(C)cccc2Cl)c2c(cnn2c1)C#N

BDBM305669

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCc2cn(C)cn2)cn2ncc(C#N)c12

BDBM305670

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OC[C@H]2CNCCO2)cn2ncc(C#N)c12 |r|

BDBM305671

CCN1CCO[C@@H](COc2cc(-c3cnc(cn3)N3CCC(C)(CC3)NC(=O)c3c(C)cccc3Cl)c3c(cnn3c2)C#N)C1 |r|

BDBM305672

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OC[C@@H]2CNCCO2)cn2ncc(C#N)c12 |r|

BDBM305673

CCN1CCO[C@H](COc2cc(-c3cnc(cn3)N3CCC(C)(CC3)NC(=O)c3c(C)cccc3Cl)c3c(cnn3c2)C#N)C1 |r|

BDBM305674

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCC2)cn2ncc(C#N)c12

BDBM305675

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCCC2)cn2ncc(C#N)c12

BDBM305676

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305677

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305678

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305679

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCN(CC2)C(=O)OC(C)(C)C)cn2ncc(C#N)c12

BDBM305680

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCNCC2)cn2ncc(C#N)c12

BDBM305681

CCN1CCN(CCOc2cc(-c3cnc(cn3)N3CCC(C)(CC3)NC(=O)c3c(C)cccc3Cl)c3c(cnn3c2)C#N)CC1

BDBM305682

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC2(F)CN(C2)C(=O)OC(C)(C)C)cn2ncc(C#N)c12

BDBM305683

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12

BDBM305684

CCN1CC(F)(COc2cc(-c3cnc(cn3)N3CCC(C)(CC3)NC(=O)c3c(C)cccc3Cl)c3c(cnn3c2)C#N)C1

BDBM305685

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12)NC(=O)c1cc(F)ccc1Cl

BDBM305686

CCN1CC(F)(COc2cc(-c3cnc(cn3)N3CCC(C)(CC3)NC(=O)c3cc(F)ccc3Cl)c3c(cnn3c2)C#N)C1

BDBM305687

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC2(F)CCNC2)cn2ncc(C#N)c12

BDBM305688

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305689

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3ncccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305690

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305691

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3cc(F)ccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305692

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3ncccc3C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305693

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3c(F)cccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305694

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3ncccc3C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305695

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](Oc3ccc(C)nn3)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305697

CCOc1cc(-c2ccc(nc2)N2CC[C@H](Oc3ccc(C)nn3)[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305698

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](OCCOC(C)C)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305699

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3Cl)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305700

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(F)cccc3Cl)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305701

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NS(=O)(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305702

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NCCC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305703

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c(Cl)cnn2c1 |r|

BDBM305704

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305705

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(F)cccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305706

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305707

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305708

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3CC(F)(F)C3)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305709

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CCC(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305710

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305711

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3Cl)[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305712

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(C)cccc3Cl)[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305713

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3C)[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305714

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)CC(C)C)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305715

CC(C)CC(=O)NC1(C)CCN(CC1)c1cnc(nc1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305716

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(nc1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305717

Cc1ccnnc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305718

Cc1nccnc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305719

Cc1ccc(nn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305720

Cc1cnc(C)c(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305721

CCOc1cc(-c2ncc(cn2)N2CCC(CC2)Oc2ccc(OC)cn2)c2c(cnn2c1)C#N

BDBM305722

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3cccnc3)CC2)c2c(cnn2c1)C#N

BDBM305723

COc1ccc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305724

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3cccc(F)c3)CC2)c2c(cnn2c1)C#N

BDBM305725

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3F)CC2)c2c(cnn2c1)C#N

BDBM305726

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccc3F)CC2)c2c(cnn2c1)C#N

BDBM305727

COc1ccccc1CC1(O)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305728

Cc1cccc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305729

Cc1ccc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1

BDBM305730

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccc(F)cc3)CC2)c2c(cnn2c1)C#N

BDBM305731

Cc1ccccc1CC1(O)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305732

Cc1cccc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1

BDBM305733

COc1cccc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305734

Cc1cnc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305735

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3Cl)CC2)c2c(cnn2c1)C#N

BDBM305736

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3cncc(F)c3)CC2)c2c(cnn2c1)C#N

BDBM305737

CCOc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM305738

CCOc1cc(-c2ccc(nc2)N2CCC(O)(Cc3cccc(F)c3)CC2)c2c(cnn2c1)C#N

BDBM305739

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccn3)CC2)c2c(cnn2c1)C#N |r|

BDBM305740

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3F)CC2)c2c(cnn2c1)C#N |r|

BDBM305741

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3Cl)CC2)c2c(cnn2c1)C#N |r|

BDBM305742

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccn3)CC2)c2c(cnn2c1)C#N |r|

BDBM305743

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3F)CC2)c2c(cnn2c1)C#N |r|

BDBM305744

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3Cl)CC2)c2c(cnn2c1)C#N |r|

BDBM305745

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(O)(Cc3ncccc3Cl)CC2)c2c(cnn2c1)C#N

BDBM305746

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(Cl)cnn2c1

BDBM305747

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(CC2)C(F)c2ccccc2)c2c(cnn2c1)C#N

BDBM305748

COc1cc(-c2cnc(cn2)N2CCC(O)(Cc3ncccc3F)CC2)c2c(cnn2c1)C#N

BDBM305749

OC1(Cc2ncccc2F)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305750

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(O)(Cc3ncccc3F)CC2)c2c(cnn2c1)C#N

BDBM305751

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(O)(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305752

COc1cc(-c2cnc(cn2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@H](O)CO)c2c(cnn2c1)C#N |r|

BDBM305753

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(F)ccc(F)c2F)c2c(cnn2c1)C#N

BDBM305754

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c(cnn2c1)C#N

BDBM305755

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305756

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305757

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305758

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2nc(C)ccc2F)c2c(cnn2c1)C#N

BDBM305759

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2nc(C)ccc2Cl)c2c(cnn2c1)C#N

BDBM305760

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2nc(C)ccc2C)c2c(cnn2c1)C#N

BDBM305761

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(C)cccc2Cl)c2c(cnn2c1)C#N

BDBM305762

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCC(C)(C)O)cn2ncc(C#N)c12

BDBM305763

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CC(F)(F)C2)cn2ncc(C#N)c12

BDBM305764

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC(=O)N2CCCC2)cn2ncc(C#N)c12

BDBM305765

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(O)cn2ncc(C#N)c12

BDBM305766

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c(cnn2c1)C#N

BDBM305767

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305768

Cc1ccc(Cl)c(n1)C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305769

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(F)ccc(F)c2F)c2c(cnn2c1)C#N

BDBM305770

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305771

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305772

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305773

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305774

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305775

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(F)ccc(F)c2F)c2c(cnn2c1)C#N

BDBM305776

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c(cnn2c1)C#N

BDBM305777

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305778

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2nc(C)ccc2Cl)c2c(cnn2c1)C#N

BDBM305779

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OC[C@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl |r|

BDBM305780

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OC[C@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1ncc(F)cc1Cl |r|

BDBM305781

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OC[C@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1cc(F)ccc1C(F)(F)F |r|

BDBM305782

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OC[C@@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl |r|

BDBM305783

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](CN)C2)c2c(cnn2c1)C#N |r|

BDBM305784

CCOc1cc(-c2ccc(nc2)N2CC[C@H](CN)C2)c2c(cnn2c1)C#N |r|

BDBM305785

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](CNC(=O)c3ncccc3Cl)C2)c2c(cnn2c1)C#N |r|

BDBM305786

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](CNC(=O)CC(C)C)C2)c2c(cnn2c1)C#N |r|

BDBM305787

CCOc1cc(-c2ccc(nc2)N2CC[C@H](CNC(=O)CC(C)C)C2)c2c(cnn2c1)C#N |r|

BDBM305788

CCOc1cc(-c2ccc(nc2)N2CC[C@H](CNC(=O)c3ncccc3Cl)C2)c2c(cnn2c1)C#N |r|

BDBM305789

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)CO)c2c(cnn2c1)C#N

BDBM305790

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)C[C@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305791

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305792

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@@H](C)OC)c2c(cnn2c1)C#N |r|

BDBM305793

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@H]2CCCN2C)c2c(cnn2c1)C#N |r|

BDBM305794

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)C(C)(C)O)c2c(cnn2c1)C#N

BDBM305795

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@H](O)CO)c2c(cnn2c1)C#N |r|

BDBM305796

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)CN(C)C)c2c(cnn2c1)C#N

BDBM305797

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@@H](N)[C@@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305798

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@@H](N)C(C)C)c2c(cnn2c1)C#N |r|

BDBM305799

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@H]2NCC[C@@H]2O)c2c(cnn2c1)C#N |r|

BDBM305800

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@@H]2[C@@H](O)CCN2CC)c2c(cnn2c1)C#N |r|

BDBM305801

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@H](O)CO)c2c(cnn2c1)C#N |r|

BDBM315629

Cc1cnc(N[C@@H]2[C@H]3C[C@@H]2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1 |r|

BDBM315689

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2ncccc2C#N)c2c(cnn2c1)C#N

BDBM315706

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)Oc2ccc(OC)nc2)c2c(cnn2c1)C#N |r|

BDBM315708

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)Oc2cnc(OC)c(F)c2)c2c(cnn2c1)C#N |r|

BDBM315710

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2ccc(OC)nc2)c2c(cnn2c1)C#N |r|

BDBM315891

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(N)CCOCC2)c2c(cnn2c1)C#N

BDBM315892

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(N)CCC2)c2c(cnn2c1)C#N

BDBM315896

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@@H]2CCN2)c2c(cnn2c1)C#N |r|

BDBM316026

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1ccc(nc1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM316054

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3cc(F)ccc3C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM315457

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCO)cn3ncc(C#N)c23)nc1

BDBM315476

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H](C)O)cn3ncc(C#N)c23)nc1 |r|

BDBM303389

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM315816

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC3CC(O)C3)cn3ncc(C#N)c23)cn1 |(12.28,-2.37,;10.95,-1.6,;9.61,-2.37,;8.28,-1.6,;6.94,-2.37,;6.94,-3.91,;5.61,-4.68,;4.28,-3.91,;2.94,-4.68,;2.94,-3.14,;4.28,-2.37,;2.94,-1.6,;1.61,-2.37,;1.61,-3.91,;.28,-1.6,;-1.06,-2.37,;-2.39,-1.6,;-2.39,-.06,;-1.06,.71,;.28,-.06,;-3.72,.71,;-5.06,-.06,;-6.39,.71,;-7.73,-.06,;-9.06,.71,;-10.55,.31,;-10.95,1.8,;-12.28,2.57,;-9.46,2.19,;-6.39,2.25,;-5.06,3.02,;-4.74,4.52,;-3.21,4.68,;-2.58,3.28,;-1.09,2.88,;.39,2.48,;-3.72,2.25,;8.28,-4.68,;9.61,-3.91,)|

BDBM304980

CCOc1cc(-c2ccc(nc2)N2CCC[C@@H](C2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM304987

CCOc1cc(-c2ccc(nc2)N2CCC[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM304988

CCOc1cc(-c2ccc(nc2)N2CCC[C@@H](C2)NC)c2c(cnn2c1)C#N |r|

BDBM304991

CCOc1cc(-c2ccc(nc2)N2CC[C@H](C)[C@@H](C2)NC)c2c(cnn2c1)C#N |r|

BDBM304992

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](O)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM304994

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ncccn2)c2c(cnn2c1)C#N

BDBM304995

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)C3O)c2c(cnn2c1)C#N

BDBM304996

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)C3OCCOC)c2c(cnn2c1)C#N

BDBM304997

CCOc1cc(-c2ccc(nc2)N2CC3C[C@@H](C2)[C@H]3Oc2ncccn2)c2c(cnn2c1)C#N |r|

BDBM304998

CCOc1cc(-c2ccc(nc2)N2CC3C[C@@H](C2)[C@H]3Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM304999

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)C3N)c2c(cnn2c1)C#N

BDBM305000

CCOc1cc(-c2ccc(nc2)N2CC3C[C@@H](C2)[C@@H]3Nc2ccc(OC)nc2)c2c(cnn2c1)C#N |r|

BDBM305001

OCCOc1cc(-c2ccc(nc2)N2CCC[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305002

N[C@H]1CCCN(C1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12 |r|

BDBM305003

CC(C)(C)OC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM305004

CC1(N)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM305005

CC(C)CC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM305006

CC(C)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM305007

CC(C)COC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM305008

CC(C)[C@@H](O)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12 |r|

BDBM305009

CC(C)NC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM305010

CC(C)CNC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM305012

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(O)CC2)c2c(cnn2c1)C#N

BDBM305014

CC(C)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM315378

COc1ccc(cn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305016

CC(C)NC(=O)C1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305017

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)C3C(=O)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305018

COc1ccc(NC(=O)C2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305020

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cccnc2)c2c(cnn2c1)C#N

BDBM305021

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM305022

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccc2)c2c(cnn2c1)C#N

BDBM305025

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305026

COc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305027

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccccc2)c2c(cnn2c1)C#N

BDBM305030

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305032

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305034

Cc1ccc(F)cc1CNC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305035

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NCc2ccccc2)c2c(cnn2c1)C#N

BDBM305036

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305037

Cc1c(F)cccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305038

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccc(F)c2F)c2c(cnn2c1)C#N

BDBM305039

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305040

Cc1cccc(F)c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305041

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccc(F)c(F)c2)c2c(cnn2c1)C#N

BDBM305042

Cc1cc(cc(C)n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305043

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccncn2)c2c(cnn2c1)C#N

BDBM305044

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cnccn2)c2c(cnn2c1)C#N

BDBM305045

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305047

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccnn2)c2c(cnn2c1)C#N

BDBM305049

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccc(F)c2)c2c(cnn2c1)C#N

BDBM305050

Cc1ccccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305051

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2C2CC2)c2c(cnn2c1)C#N

BDBM305052

COc1ccccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305053

COc1cccc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305054

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccc(c2)C2CC2)c2c(cnn2c1)C#N

BDBM305055

COc1cccc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305056

Cc1c(Cl)cccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305057

Cc1ccc(Cl)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305058

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2C#N)c2c(cnn2c1)C#N

BDBM305059

CCc1ccccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305060

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2S(C)(=O)=O)c2c(cnn2c1)C#N

BDBM305061

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2F)c2c(cnn2c1)C#N

BDBM305064

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM305065

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2F)c2c(cnn2c1)C#N

BDBM305066

CCc1cccc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305068

COc1cccnc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305069

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccn2)c2c(cnn2c1)C#N

BDBM305070

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccc(Cl)c2)c2c(cnn2c1)C#N

BDBM305072

Cc1ccc(C)c(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305073

COc1ncc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305074

COc1ccnc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305075

Cc1ccc(cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)C#N

BDBM305076

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM305077

Cc1cc(F)ccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305078

Cc1ccc(F)c(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305079

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c[nH]ccc2=O)c2c(cnn2c1)C#N

BDBM305080

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(=O)cc[nH]2)c2c(cnn2c1)C#N

BDBM305081

Cn1cccc(C(=O)NC2(C)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1=O

BDBM305082

Cc1cc(=O)cc(C(=O)NC2(C)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1C

BDBM305083

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2[nH]c(=O)ccc2F)c2c(cnn2c1)C#N

BDBM305084

COCc1cccc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305085

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305086

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c(F)cccc2Cl)c2c(cnn2c1)C#N

BDBM305087

Cc1cc(C)nc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305088

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305090

COc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305091

COc1ccc(F)c(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305092

COc1c(F)cc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305093

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccc(CO)c2)c2c(cnn2c1)C#N

BDBM305094

CN1CCc2c(C1)cccc2C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305095

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305096

Cc1cccc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305097

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccnc2)c2c(cnn2c1)C#N

BDBM305098

CC(C)(C)CC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305099

Cc1ccc(nc1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305100

CCC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305101

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2CC2)c2c(cnn2c1)C#N

BDBM305102

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)CC(F)(F)F)c2c(cnn2c1)C#N

BDBM305103

Cc1ccnc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305104

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C(C)(C)c2ccccc2)c2c(cnn2c1)C#N

BDBM305105

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C(C)(C)c2ccc(Cl)cc2)c2c(cnn2c1)C#N

BDBM305015

Cc1ccc(cn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305107

Cc1ncccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305108

Cc1cccnc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305109

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)Cc2ccccc2)c2c(cnn2c1)C#N

BDBM305110

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)CC(C)(C)c2ccccc2)c2c(cnn2c1)C#N

BDBM305111

Cc1ccncc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305112

Cc1cncc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305113

COc1cccc(C(=O)NC2(C)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1C

BDBM305114

COc1ccc(C)c(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305115

Cc1cccc(C)c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305116

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2F)c2c(cnn2c1)C#N

BDBM305117

Cc1ccc(F)c(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305118

Cc1cc(ccn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305119

COc1cc(OC)nc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305120

Cc1ccnc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305121

Cc1ncncc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305122

Cc1cc(=O)cc([nH]1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305123

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)cc(F)c2Cl)c2c(cnn2c1)C#N

BDBM305124

Cc1cc(C(=O)NC2(C)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c(Cl)cn1

BDBM305125

Cc1cc(C)nc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305126

CN(C)Cc1cccc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305127

Cc1ccc(=O)[nH]c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305128

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2Cl)c2c(cnn2c1)C#N

BDBM305129

Cc1c(Cl)cncc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305130

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c(F)ccc(F)c2F)c2c(cnn2c1)C#N

BDBM305131

Cc1cc(C(=O)NC2(C)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c(F)cn1

BDBM305132

Cc1c(cnn1C)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305133

Cn1cc(cn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305134

Cc1nn(C)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305135

Cc1nc(co1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305136

Cn1ccc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305137

Cc1ncn(C)c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305138

CC(C)n1cc(cn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305139

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2cccnc2)c2c(cnn2c1)C#N

BDBM305140

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccc(cc2)C#N)c2c(cnn2c1)C#N

BDBM305141

Cc1cccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305142

COCCOC1CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305143

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccccc2F)c2c(cnn2c1)C#N

BDBM305144

COc1cncc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305145

Cc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1

BDBM305146

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2cccc(Cl)c2)c2c(cnn2c1)C#N

BDBM305147

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccc(cc2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM305148

Cc1cccnc1OC1CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305149

Cc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM305150

Cn1nccc1OC1CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305151

COc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM305152

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2cccc(F)c2)c2c(cnn2c1)C#N

BDBM305153

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM305154

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccc(F)cn2)c2c(cnn2c1)C#N

BDBM305155

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccc(Cl)cn2)c2c(cnn2c1)C#N

BDBM305156

Cc1ccccc1OC1CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305157

CC(C)OC1CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305158

COc1ncc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1F

BDBM305159

Cc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM305160

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C)(C2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305161

COc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305162

COc1cnc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305163

COc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM305164

COc1ncc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305165

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2cccc(c2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM305166

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2cccc(n2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM305167

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccc(Cl)cc2)c2c(cnn2c1)C#N

BDBM305168

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccc(F)cc2F)c2c(cnn2c1)C#N

BDBM305169

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM305170

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccc(F)c(F)c2)c2c(cnn2c1)C#N

BDBM305171

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2cc(F)cc(F)c2)c2c(cnn2c1)C#N

BDBM305172

COc1ncc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1Cl

BDBM305173

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2cncc(F)c2)c2c(cnn2c1)C#N

BDBM305174

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)OCc2ccccc2)c2c(cnn2c1)C#N

BDBM305175

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Nc2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM305176

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccc(OC(F)F)nc2)c2c(cnn2c1)C#N

BDBM305177

Cc1ccnc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305178

COc1ccnc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305179

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(C2)OCc2ccccn2)c2c(cnn2c1)C#N

BDBM305180

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC(COc3ccccn3)C2)c2c(cnn2c1)C#N

BDBM305181

Cc1ccc(F)cc1C(=O)NC1(C)CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305182

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@H](C2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305183

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305184

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)N2CCCCC2)c2c(cnn2c1)C#N

BDBM305187

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2ccc(F)cc2)c2c(cnn2c1)C#N |r|

BDBM305190

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2ccc(F)cn2)c2c(cnn2c1)C#N |r|

BDBM305192

Cc1cccc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1 |r|

BDBM305193

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2cncc(F)c2)c2c(cnn2c1)C#N |r|

BDBM305197

COc1ncc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1Cl |r|

BDBM305198

C[C@@H]1CN(C[C@H]1Oc1ccccn1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM305199

COc1nc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)ccc1F |r|

BDBM305200

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)N2CCCC2=O)c2c(cnn2c1)C#N

BDBM305201

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305202

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)NCc2ccccc2)c2c(cnn2c1)C#N

BDBM305203

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305204

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305205

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)Cc2ccccc2)c2c(cnn2c1)C#N

BDBM305206

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)C(=O)Nc1ccccc1

BDBM305207

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305208

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305209

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)Cc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305210

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)c2cccc(F)c2F)c2c(cnn2c1)C#N |r|

BDBM305211

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N |r|

BDBM305212

Cc1ccc(F)cc1C(=O)N[C@]1(C)CCN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM305213

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N |r|

BDBM305214

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)C2CC2)c2c(cnn2c1)C#N |r|

BDBM305215

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305216

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)Cc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305217

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2cccc(F)c2F)c2c(cnn2c1)C#N |r|

BDBM305218

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N |r|

BDBM305219

Cc1ccc(F)cc1C(=O)N[C@@]1(C)CCN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM305220

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2ncccc2F)c2c(cnn2c1)C#N |r|

BDBM305222

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)C2CC2)c2c(cnn2c1)C#N |r|

BDBM305231

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ncccn2)c2c(cnn2c1)C#N

BDBM305232

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cnccn2)c2c(cnn2c1)C#N

BDBM305233

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(Cl)cn2)c2c(cnn2c1)C#N

BDBM305234

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ncc(Cl)cc2F)c2c(cnn2c1)C#N

BDBM305235

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cncc(Cl)c2)c2c(cnn2c1)C#N

BDBM305236

COc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM305237

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(F)cn2)c2c(cnn2c1)C#N

BDBM305238

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(cn2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM305239

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305240

COc1cnc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305241

COc1ncc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305242

COc1ncc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1F

BDBM305243

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(OC(F)F)nc2)c2c(cnn2c1)C#N

BDBM305244

CC(C)OCCOC1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305245

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)OCc2ccccc2)c2c(cnn2c1)C#N

BDBM305246

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)OCc2ccccn2)c2c(cnn2c1)C#N

BDBM305247

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(COc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305248

COc1ncc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1Cl

BDBM305249

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cncc(F)c2)c2c(cnn2c1)C#N

BDBM305250

COc1ccnc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305251

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cccnn2)c2c(cnn2c1)C#N

BDBM305252

COc1nnc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1C

BDBM305253

CCc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM305254

Cc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM305255

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(Cl)cc2)c2c(cnn2c1)C#N

BDBM305256

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(cc2)C#N)c2c(cnn2c1)C#N

BDBM305257

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cccc(F)c2)c2c(cnn2c1)C#N

BDBM305258

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccc2F)c2c(cnn2c1)C#N

BDBM415965

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccc2C#N)c2c(cnn2c1)C#N

BDBM305260

COC1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305263

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)C(=O)NCC(C)C

BDBM305264

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Nc2ccccn2)c2c(cnn2c1)C#N

BDBM305265

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3Nc2ncccn2)c2c(cnn2c1)C#N |r|

BDBM305271

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3NC(=O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305272

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3NC(=O)c2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305273

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N

BDBM305274

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2cccc(F)c2)c2c(cnn2c1)C#N

BDBM305275

CC(C)C(=O)NC1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305276

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305277

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2cccnc2)c2c(cnn2c1)C#N

BDBM305278

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM305279

CC(C)CNC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305280

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC2CCCO2)c2c(cnn2c1)C#N

BDBM305281

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC2CCOCC2)c2c(cnn2c1)C#N

BDBM305282

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC2CCCOC2)c2c(cnn2c1)C#N

BDBM305283

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM305284

Cc1ccc(F)cc1NC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305291

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC2(C)CNC2)cn2ncc(C#N)c12

BDBM305293

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCNCC2)cn2ncc(C#N)c12

BDBM305297

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)N(C)C(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305304

CC(C)(C)OC(=O)NCCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305310

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CCc3cccnc3)CC2)c2c(cnn2c1)C#N

BDBM305311

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CC2)c2ccccc2)c2c(cnn2c1)C#N

BDBM305312

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CC2)c2ccccn2)c2c(cnn2c1)C#N

BDBM305313

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CC2)c2cccnc2)c2c(cnn2c1)C#N

BDBM305314

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CC2)c2ccncc2)c2c(cnn2c1)C#N

BDBM305315

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(C)nn2)c2c(cnn2c1)C#N

BDBM305316

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(Cl)nc2)c2c(cnn2c1)C#N

BDBM305317

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(OCCO)nc2)c2c(cnn2c1)C#N

BDBM305330

CCOc1cc(-c2ccc(nc2)N2CCC[C@H](C2)NCc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305331

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](C)[C@H](C2)NC)c2c(cnn2c1)C#N |r|

BDBM305332

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)C[C@@H](C2)C(F)(F)F)c2c(cnn2c1)C#N |r|

BDBM305333

CCOc1cc(-c2ccc(nc2)N2C[C@@H](C[C@@H](C2)C(F)(F)F)NC)c2c(cnn2c1)C#N |r|

BDBM305334

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305335

CCCO[C@H]1CN(C[C@@H]1N)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12 |r|

BDBM305336

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)OCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305337

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)OCCOC(C)C)c2c(cnn2c1)C#N |r|

BDBM305338

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305339

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)OCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305340

CCCO[C@@H]1CN(C[C@H]1N)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12 |r|

BDBM305341

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)OCCOC(C)C)c2c(cnn2c1)C#N |r|

BDBM305344

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)Oc2ccc(Cl)nn2)c2c(cnn2c1)C#N |r|

BDBM305348

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2ccc(Cl)nn2)c2c(cnn2c1)C#N |r|

BDBM305349

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305350

CCOc1cc(-c2ccc(nc2)N2CC[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305351

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)C[C@H](C2)C(F)(F)F)c2c(cnn2c1)C#N |r|

BDBM305354

CCOc1cc(-c2ccc(nc2)N2CCC(CC)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305357

CCOc1cc(-c2ccc(nc2)N2CCC(N)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305364

CCOc1cc(-c2ccc(nc2)N2CCC(CNCC(C)(C)O)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305365

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CC(F)(F)CO)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305388

O=C1CCCN1CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305391

CN(C)C(=O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305392

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305393

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305394

OC1(Cc2ccccn2)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305395

OC1(Cc2ccccc2)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305398

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(C)nn2)c2c(cnn2c1)C#N |r|

BDBM305399

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305401

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2ccnn2c1

BDBM305402

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c(F)cccc2Cl)c2ccnn2c1

BDBM305403

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2ccnn2c1

BDBM305409

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(cc2)C#N)c2c(Cl)cnn2c1

BDBM305411

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2ccccn2)c2c(Cl)cnn2c1 |r|

BDBM305413

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Nc2ccccc2)c2c(Cl)cnn2c1

BDBM305423

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ccccc1

BDBM305427

CC(=O)N1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccc3)c3c(cnn3c2)C#N)CC1

BDBM305430

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305431

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccnc2)c2c(cnn2c1)C#N

BDBM305432

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NCc2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305449

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305450

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)N2CCCC2)c2c(cnn2c1)C#N

BDBM305451

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305452

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM305453

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2cccnc2)c2c(cnn2c1)C#N

BDBM305454

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccc(C)nc2)c2c(cnn2c1)C#N

BDBM305455

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccc(C)cn2)c2c(cnn2c1)C#N

BDBM305457

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC2CC2)c2c(cnn2c1)C#N

BDBM305458

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)N[C@H](C)C(C)C)c2c(cnn2c1)C#N |r|

BDBM305459

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)N[C@@H](C)C(C)C)c2c(cnn2c1)C#N |r|

BDBM305460

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC(F)(F)F)c2c(cnn2c1)C#N

BDBM305461

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NC[C@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305462

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(N)CC2)c2c(cnn2c1)C#N

BDBM305464

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Sc2ccccn2)c2c(cnn2c1)C#N

BDBM305466

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3N)c2c(cnn2c1)C#N |r|

BDBM305467

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(N)CC2)c2c(cnn2c1)C#N

BDBM305468

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(O)cn2ncc(C#N)c12

BDBM305469

CCOc1cc(-c2ccc(nc2)N2CCC(C)(N)CC2)c2c(cnn2c1)C#N

BDBM305471

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ncccc2F)c2c(cnn2c1)C#N

BDBM416209

CCOc1cc(-c2ccc(nc2)N2CCC(NC(=O)CC(C)C)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305578

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)C(C)C)c2c(cnn2c1)C#N

BDBM305598

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CC(F)F)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305599

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCC(F)(F)C3)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM416357

CC(C)C(C)OC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM767006

Cc1cc(Nc2cc(C)[nH]n2)nc(-c2ccc(N3CC4CC(C3)N4Cc3ccc(-n4cccn4)nc3)nc2)n1

BDBM767007

Cc1cc(Nc2cc(C)[nH]n2)nc(-c2ccc(N3CC4CC(C3)N4Cc3ccc(-n4cc(F)cn4)nc3)nc2)n1

BDBM767012

COC1(C(=O)N[C@H](C)c2ccc(-n3cc(F)cn3)nc2)CCC(c2nc(C)cc(Nc3cc(C)[nH]n3)n2)CC1

BDBM767014

Cc1cc(Nc2cc(C)[nH]n2)nc(-c2ccc(N3CC4CC(C3)N4Cc3ccc(-n4cc(F)cn4)nc3)nc2)n1

BDBM477400

COc1cc(-c2ccc(nc2)N2CCC(NC(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM477541

CCOc1cc(-c2ccc(nc2)N2CCC(NC(=O)CC3CNCCO3)C(Cc3ccccn3)C2)c2c(cnn2c1)C#N

BDBM477628

CCOc1cc(-c2ccc(nc2)N2CCC(Oc3ccc(C)nn3)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM477631

CCOc1cc(-c2ccc(nc2)N2CCC(OCCOC(C)C)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM477643

CCOc1cc(-c2ccc(nc2)N2CCC(NC(=O)CC(C)C)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM430529

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)[C@H](N(C)C)c2cccc(Cl)c2)c2c(cnn2c1)C#N |r|

BDBM576971

CC(C)n1nc(-c2cc(on2)C2(O)CC2)c2c(N)nccc12

BDBM576972

CC(C)n1nc(-c2cc(on2)C2CC2)c2c(N)nccc12

BDBM576973

CC(C)n1nc(-c2cc(on2)C2CC2)c2c(N)ncc(Cl)c12

BDBM576977

CC(C)n1nc(-c2noc(C3CC3)c2Br)c2c(N)nccc12

BDBM576983

CC(C)n1nc(-c2noc(C3CC3)c2I)c2c(N)nccc12

BDBM576985

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)nccc12

BDBM576986

CC(C)n1nc(-c2noc(C3CC3)c2-c2ncccc2F)c2c(N)nccc12 |(1.18,-4.89,;-.31,-4.49,;-1.4,-5.58,;-.71,-3,;.19,-1.76,;-.76,-.5,;-.32,1.09,;-1.22,2.33,;-.24,3.52,;1.25,3,;2.34,4.09,;3.83,4.49,;2.74,5.58,;1.09,1.51,;2.28,.52,;2.01,-1,;3.2,-1.98,;4.64,-1.45,;4.91,.06,;3.72,1.05,;3.99,2.57,;-2.2,-.97,;-3.57,-.22,;-3.57,1.27,;-4.91,-1.02,;-4.88,-2.51,;-3.52,-3.26,;-2.2,-2.49,)|

BDBM576988

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncc(Cl)c12

BDBM576991

CC(C)n1nc(-c2cc(on2)C2CC2)c2c(N)ncc(F)c12

BDBM576995

CC(C)n1nc(-c2noc(C3CC3)c2I)c2c(N)ncc(F)c12

BDBM576996

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncc(F)c12

BDBM576998

CC(C)n1nc(-c2cc(nn2C2CCCCO2)C2CC2)c2c(N)nccc12

BDBM577002

CC(C)n1nc(-c2cc(nn2C2CCCCO2)C2CC2)c2c(N)ncc(Cl)c12

BDBM577003

CC(C)n1nc(-c2cc(nn2C2CCCCO2)C2CC2)c2c(N)ncc(Br)c12

BDBM577004

CC(C)n1nc(-c2cc(nn2C2CCCCO2)C2CC2)c2c(N)ncc(C)c12

BDBM577005

CC(C)n1nc(-c2cc(nn2C2CCCCO2)C2CC2)c2c(N)ncc(C#N)c12

BDBM577006

CC(C)n1nc(-c2noc(C3CC3)c2C2=CCCC2=O)c2c(N)nccc12 |t:16|

BDBM577007

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccn(C)n2)c2c(N)nccc12

BDBM577008

CC(C)n1nc(-c2noc(C3CC3)c2C2=CCCCO2)c2c(N)nccc12 |t:16|

BDBM577009

CC(C)n1nc(-c2noc(C3CC3)c2C)c2c(N)nccc12

BDBM577010

CC(C)n1nc(-c2cc(on2)C(C)(C)O)c2c(N)nccc12

BDBM577011

CC(C)n1nc(-c2cc(on2)C2(O)CCC2)c2c(N)nccc12

BDBM577012

CC(C)n1nc(-c2cc(on2)C2(O)COC2)c2c(N)nccc12

BDBM577013

CC(C)n1nc(-c2noc(C3CC3)c2-c2cnccn2)c2c(N)nccc12

BDBM577015

CC(C)n1nc(-c2noc(C3CC3)c2-c2cc(C)ccn2)c2c(N)nccc12

BDBM577017

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccc(cn2)C(F)(F)F)c2c(N)nccc12

BDBM577018

CC(C)n1nc(-c2noc(C3CC3)c2-c2cccc(C)n2)c2c(N)nccc12

BDBM577019

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccc(C)cn2)c2c(N)nccc12

BDBM577020

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccc(Cl)cn2)c2c(N)nccc12

BDBM577021

CC(C)n1nc(-c2noc(C3CC3)c2-c2ncccn2)c2c(N)nccc12

BDBM577022

CC(C)n1nc(-c2noc(C3CC3)c2-c2cn(C)cn2)c2c(N)nccc12

BDBM577025

CC(C)n1nc(-c2noc(C3CC3)c2-c2cnccn2)c2c(N)ncc(Cl)c12

BDBM577026

CC(C)n1nc(-c2noc(C3CC3)c2-c2cc(C)ccn2)c2c(N)ncc(Cl)c12

BDBM577027

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccc(cn2)C(F)(F)F)c2c(N)ncc(Cl)c12

BDBM577028

CC(C)n1nc(-c2noc(C3CC3)c2-c2cccc(C)n2)c2c(N)ncc(Cl)c12

BDBM577029

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccc(C)cn2)c2c(N)ncc(Cl)c12

BDBM577030

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccc(Cl)cn2)c2c(N)ncc(Cl)c12

BDBM577031

CC(C)n1nc(-c2cc(on2)C(C)(C)O)c2c(N)ncc(Cl)c12

BDBM577032

CC(C)n1nc(-c2cc(on2)C2(O)COC2)c2c(N)ncc(Cl)c12

BDBM577033

CC(C)n1nc(-c2noc(c2-c2ccccn2)C(C)(C)O)c2c(N)nccc12

BDBM577035

CC(C)n1nc(-c2noc(c2-c2ccccn2)C(C)(C)O)c2c(N)ncc(Cl)c12

BDBM577036

CC(C)n1nc(-c2noc(C)c2-c2ccccn2)c2c(N)nccc12

BDBM577037

CC(C)n1nc(-c2noc(C)c2-c2ccccn2)c2c(N)ncc(Cl)c12

BDBM577038

CC(C)n1nc(-c2noc(C3CC3)c2-c2cnn(C)c2)c2c(N)nccc12

BDBM577039

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccc[nH]c2=O)c2c(N)nccc12 |(-1.39,-5.57,;-.3,-4.49,;1.19,-4.88,;-.7,-3,;.21,-1.75,;-.7,-.51,;-.3,.98,;-1.2,2.23,;-.3,3.47,;1.16,3,;2.25,4.09,;3.74,4.49,;2.65,5.57,;1.16,1.46,;2.25,.37,;1.86,-1.12,;2.94,-2.21,;4.43,-1.81,;4.83,-.32,;3.74,.77,;4.14,2.25,;-2.16,-.98,;-3.5,-.21,;-3.5,1.33,;-4.83,-.98,;-4.83,-2.52,;-3.5,-3.29,;-2.16,-2.52,)|

BDBM577040

CC(C)n1nc(-c2noc(C3CC3)c2CO)c2c(N)nccc12

BDBM577041

COCc1c(noc1C1CC1)-c1nn(C(C)C)c2ccnc(N)c12

BDBM577042

CNC(=O)c1c(noc1C1CC1)-c1nn(C(C)C)c2ccnc(N)c12

BDBM577043

CC(C)n1nc(-c2noc(C3CC3)c2C(N)=O)c2c(N)nccc12

BDBM577044

CC(C)n1nc(-c2noc(C3CC3)c2C(=O)NC2C[C@H](O)C2)c2c(N)nccc12 |r,wU:19.21,(-.92,-4.6,;-2.28,-3.88,;-3.59,-4.7,;-2.34,-2.34,;-1.12,-1.39,;-1.65,.05,;-.9,1.4,;-1.38,2.87,;-.13,3.77,;1.11,2.87,;2.53,3.47,;4.06,3.28,;3.46,4.7,;.64,1.4,;1.52,.14,;.87,-1.26,;3.05,.27,;3.97,-.97,;3.74,-2.49,;5.26,-2.72,;6.18,-3.96,;5.49,-1.2,;-3.19,-0,;-4.26,1.11,;-3.83,2.59,;-5.75,.74,;-6.18,-.75,;-5.11,-1.85,;-3.61,-1.48,)|

BDBM577045

CC(C)n1nc(-c2noc(C3CC3)c2-c2cc(C)[nH]n2)c2c(N)ncc(Cl)c12

BDBM577046

CC(C)n1nc(-c2noc(C3CC3)c2-c2cc[nH]n2)c2c(N)ncc(Cl)c12

BDBM577047

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccn(C)n2)c2c(N)ncc(Cl)c12

BDBM577048

CCn1ccc(n1)-c1c(noc1C1CC1)-c1nn(C(C)C)c2c(Cl)cnc(N)c12

BDBM577049

CC(C)n1nc(-c2noc(C3CC3)c2-c2cn(C)cn2)c2c(N)ncc(Cl)c12

BDBM577050

CC(C)n1nc(-c2noc(C3CC3)c2-c2c[nH]cn2)c2c(N)ncc(Cl)c12

BDBM577051

CC(C)n1nc(-c2noc(C3CC3)c2-c2cccnn2)c2c(N)ncc(Cl)c12

BDBM577053

CC(C)n1nc(-c2noc(C3CC3)c2-c2c[nH]cn2)c2c(N)nccc12

BDBM577054

CC(C)n1nc(-c2noc(C3CC3)c2C(C)=O)c2c(N)nccc12

BDBM577055

CC(C)n1nc(-c2noc(C3CC3)c2-c2c[nH]nn2)c2c(N)nccc12

BDBM577056

CC(C)n1nc(-c2noc(C3CC3)c2N2CCOCC2=O)c2c(N)nccc12

BDBM577057

CC(C)n1nc(-c2noc(C3CC3)c2N2CCC2=O)c2c(N)nccc12

BDBM577059

CC(C)n1nc(-c2noc(C3CC3)c2N2CCCC2=O)c2c(N)nccc12

BDBM577060

CC(C)n1nc(-c2noc(C3CC3)c2N2CCN(C)C2=O)c2c(N)nccc12

BDBM577061

CC(C)n1nc(-c2noc(C3CC3)c2N2CCC2=O)c2c(N)ncc(Cl)c12

BDBM577062

CC(C)n1nc(-c2noc(C3CC3)c2N2CCCC2=O)c2c(N)ncc(Cl)c12

BDBM577063

CC(C)n1nc(-c2noc(C3CC3)c2N2CCN(C)C2=O)c2c(N)ncc(Cl)c12

BDBM577064

CC(C)n1nc(-c2noc(C3CC3)c2-c2cn(C)cn2)c2c(N)ncc(F)c12

BDBM577065

CC(C)n1nc(-c2noc(C3CC3)c2-c2ccn(C)n2)c2c(N)ncc(F)c12

BDBM577066

CC(C)n1nc(-c2noc(C3CC3)c2-c2cc[nH]n2)c2c(N)ncc(F)c12

BDBM577067

CC(C)n1nc(-c2noc(C3CC3)c2-c2cc(C)[nH]n2)c2c(N)ncc(F)c12

BDBM577068

CC(C#N)n1nc(-c2cc(on2)C2CC2)c2c(N)ncc(F)c12

BDBM577069

Cn1ccc(n1)-c1c(noc1C1CC1)-c1nn(C(CF)CF)c2ccnc(N)c12

BDBM577070

Cn1ccc(n1)-c1c(noc1C1CC1)-c1nn(C)c2ccnc(N)c12

BDBM577071

Cn1ccc(n1)-c1c(noc1C1CC1)-c1nn(C2CCCC2)c2ccnc(N)c12

BDBM577072

Cn1ccc(n1)-c1c(noc1C1CC1)-c1nn(CC(C)(C)O)c2ccnc(N)c12

BDBM577073

CC(C)n1nc(-c2nc(Br)ns2)c2c(N)nccc12

BDBM577074

CC(C)n1nc(-c2noc(C3CC3)c2-c2cnn(Cc3ccccc3)c2)c2c(N)nccc12

BDBM577075

CC(C)n1nc(-c2noc(C3CC3)c2P(C)(C)=O)c2c(N)ncc(F)c12

BDBM597646

CC(C)n1cc(-c2noc(C3CC3)c2I)c2c(N)ncnc12

BDBM597647

CC(C)n1cc(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncnc12

BDBM597648

CC(C)n1cc(-c2cc(on2)C2CC2)c2c(N)ncnc12

BDBM597649

CC(C)(C)n1cc(-c2cc(on2)C2CC2)c2c(N)ncnc12

BDBM597650

CC(C)(C)n1cc(-c2cnn(c2)C2CC2)c2c(N)ncnc12

BDBM597651

CC(C)(C)n1cc(-c2cc(nn2C2CCCCO2)C2CC2)c2c(N)ncnc12

BDBM597652

CC(C)(C)n1cc(-c2c[nH]nn2)c2c(N)ncnc12

BDBM597653

CCn1cc(nn1)-c1cn(c2ncnc(N)c12)C(C)(C)C

BDBM597654

CCn1cc(nn1)-c1cn(c2ncnc(N)c12)C(C)(C)C1CC1

BDBM597655

CC(C)(C1CC1)n1cc(-c2cn(nn2)C2CC2)c2c(N)ncnc12

BDBM597656

CC(C)n1cc(-c2cc(nn2C2CCCCO2)C2CC2)c2c(N)ncnc12

BDBM597657

Nc1ncnc2[nH]cc(-c3cc(on3)C3CC3)c12

BDBM597658

CC(C)n1c(C=O)c(-c2cc(on2)C2CC2)c2c(N)ncnc12

BDBM597659

CC(C)n1c(CO)c(-c2cc(on2)C2CC2)c2c(N)ncnc12

BDBM597660

CC(C)n1cc(-c2noc(C3CC3)c2C(N)=O)c2c(N)ncnc12

BDBM597661

CNC(=O)c1c(noc1C1CC1)-c1cn(C(C)C)c2ncnc(N)c12

BDBM597662

Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)C1CCCC1

BDBM597663

Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)C1CCC1

BDBM597664

Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)C1CCOCC1

BDBM597665

Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)C1CC1

BDBM597666

Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)-c1ccccc1

BDBM597667

Nc1ncnc2n(Cc3ccccc3)cc(-c3cc(on3)C3CC3)c12

BDBM597668

CC(C#N)n1cc(-c2cc(on2)C2CC2)c2c(N)ncnc12

BDBM597669

CC(n1cc(-c2cc(on2)C2CC2)c2c(N)ncnc12)C(F)(F)F

BDBM597670

CC(C)(O)Cn1cc(-c2cc(on2)C2CC2)c2c(N)ncnc12

BDBM597671

Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)C1COC1

BDBM597672

Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)C1CC(CO)C1 |(-2.78,4.69,;-3.17,3.2,;-4.68,2.88,;-5.16,1.42,;-4.13,.27,;-2.62,.59,;-1.37,-.31,;-.13,.59,;-.6,2.06,;.17,3.39,;1.71,3.39,;2.18,4.85,;.94,5.76,;-.31,4.85,;3.67,5.25,;5.16,4.85,;4.76,6.34,;-2.14,2.06,;-1.37,-1.85,;-2.46,-2.94,;-1.37,-4.03,;-1.37,-5.57,;-.04,-6.34,;-.29,-2.94,)|

BDBM597673

Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)[C@@H]1C[C@H](CO)C1 |r,wU:18.21,20.24,(-2.78,4.69,;-3.17,3.2,;-4.68,2.88,;-5.16,1.42,;-4.13,.27,;-2.62,.59,;-1.37,-.31,;-.13,.59,;-.6,2.06,;.17,3.39,;1.71,3.39,;2.18,4.85,;.94,5.76,;-.31,4.85,;3.67,5.25,;5.16,4.85,;4.76,6.34,;-2.14,2.06,;-1.37,-1.85,;-2.46,-2.94,;-1.37,-4.03,;-1.37,-5.57,;-.04,-6.34,;-.29,-2.94,)|

BDBM597674

Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)[C@H]1C[C@H](CO)C1 |r,wU:18.21,wD:20.24,(-2.78,4.69,;-3.17,3.2,;-4.68,2.88,;-5.16,1.42,;-4.13,.27,;-2.62,.59,;-1.37,-.31,;-.13,.59,;-.6,2.06,;.17,3.39,;1.71,3.39,;2.18,4.85,;.94,5.76,;-.31,4.85,;3.67,5.25,;5.16,4.85,;4.76,6.34,;-2.14,2.06,;-1.37,-1.85,;-.29,-2.94,;-1.37,-4.03,;-1.37,-5.57,;-.04,-6.34,;-2.46,-2.94,)|

BDBM597675

CC(C)n1cc(-c2noc(C3CC3)c2C(O)CO)c2c(N)ncnc12

BDBM597676

CC(C)n1c(C)c(-c2noc(C3CC3)c2-c2ccccn2)c2c(N)ncnc12 |(-1.41,-5.45,;-.38,-4.3,;1.13,-4.62,;-.85,-2.84,;.05,-1.59,;1.59,-1.59,;-.85,-.35,;-.38,1.12,;-1.28,2.36,;-.38,3.61,;1.09,3.13,;2.33,4.04,;3.86,4.2,;2.96,5.45,;1.09,1.59,;2.33,.69,;2.17,-.84,;3.42,-1.75,;4.82,-1.12,;4.99,.41,;3.74,1.32,;-2.32,-.82,;-3.65,-.05,;-3.65,1.49,;-4.99,-.82,;-4.99,-2.36,;-3.65,-3.13,;-2.32,-2.36,)|

BDBM597677

CC(C)n1c(C)c(-c2cc(on2)C2CC2)c2c(N)ncnc12

BDBM597678

CC(C)n1c(C)c(-c2noc(C3CC3)c2-c2cn(C)cn2)c2c(N)ncnc12 |(-1.27,-5.45,;-.24,-4.3,;1.27,-4.62,;-.71,-2.84,;.19,-1.59,;1.73,-1.59,;-.71,-.35,;-.24,1.12,;-1.14,2.36,;-.24,3.61,;1.23,3.13,;2.47,4.04,;4.01,4.2,;3.1,5.45,;1.23,1.59,;2.47,.69,;2.47,-.85,;3.94,-1.33,;4.41,-2.79,;4.84,-.08,;3.94,1.17,;-2.18,-.82,;-3.51,-.05,;-3.51,1.49,;-4.84,-.82,;-4.84,-2.36,;-3.51,-3.13,;-2.18,-2.36,)|

BDBM597679

CC(C)n1c(CN)c(-c2cc(C)n[nH]2)c2c(N)ncnc12

BDBM602610

OC(=O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM602635

COc1ccc(NC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(Cl)c23)cn1

BDBM602642

Cn1cnc(COC2=CN3N=CC(C#N)C3C(=C2)c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2)c1 |c:10,17,t:7|

BDBM602643

CC1(CCN(CC1)c1ccc(cn1)C1=CC(OCCN2CCCC2)=CN2N=CC(C#N)C12)NC(=O)c1ccccc1 |c:26,29,t:15|

BDBM602649

CC1(CCN(CC1)c1ccc(cn1)-c1cc(O)cn2ncc(C#N)c12)NC(=O)c1ccccc1

BDBM602655

CCOC1=CN2N=CC(C#N)C2C(=C1)c1ccc(nc1)N1CCC(C)(CC1)NC(=O)CC(C)C |c:6,13,t:3|

BDBM602656

CCOC1=CN2N=CC(C#N)C2C(=C1)c1ccc(nc1)N1CCC(C)(CC1)NC(=O)OC(C)C |c:6,13,t:3|

BDBM602658

Cn1cnc(COC2=CN3N=CC(C#N)C3C(=C2)c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccn2)c1 |c:10,17,t:7|

BDBM602659

CC1(CCN(CC1)c1ccc(cn1)C1=CC(OCCCN2CCOCC2)=CN2N=CC(C#N)C12)NC(=O)c1ccccn1 |c:28,31,t:15|

BDBM602660

CC1(CCN(CC1)c1ccc(cn1)C1=CC(OCCn2ccnc2)=CN2N=CC(C#N)C12)NC(=O)c1ccccn1 |c:26,29,t:15|

BDBM602661

Cn1ccnc1COC1=CN2N=CC(C#N)C2C(=C1)c1ccc(nc1)N1CCC(C)(CC1)NC(=O)c1ccccn1 |c:12,19,t:9|

BDBM602662

CC1(CCN(CC1)c1ccc(cn1)C1=CC(OCCN2CCCC2)=CN2N=CC(C#N)C12)NC(=O)c1ccccn1 |c:26,29,t:15|

BDBM602720

CCOc1cc(-c2ccc(nc2)C2CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](C2)OCCN(C)C)c2c(cnn2c1)C#N |r|

BDBM602721

CCOc1cc(-c2ccc(nc2)C2CC[C@H](NC(=O)OC(C)(C)C)[C@H](C2)OCCN(C)C)c2c(cnn2c1)C#N |r|

BDBM602753

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@H](C)N)c2c(cnn2c1)C#N |r|

BDBM602795

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC[C@H](O)CC)c2c(cnn2c1)C#N |r|

BDBM602806

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC[C@H](C)N(C)CC3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N |r|

BDBM602807

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC[C@H](C)N(C)CC3)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N |r|

BDBM602808

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC[C@H](C)N(CC3)C(=O)OC(C)(C)C)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N |r|

BDBM602809

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN[C@@H](C)CC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N |r|

BDBM602810

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC[C@H](C)N(C)CC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N |r|

BDBM602811

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC[C@H](C)N(C)CC3)(CC2)NC(=O)Oc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM602822

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM602832

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@@H](N)C[C@@H](C)O)c2c(cnn2c1)C#N |r|

BDBM602955

Cc1cnc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM677855

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C)c2c3cn[nH]c3nn2c1

BDBM677844

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677845

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c3cn[nH]c3nn2c1

BDBM677856

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(OC)nn2)c2c3cn[nH]c3nn2c1

BDBM677846

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2c(F)cccc2F)c2c3cn[nH]c3nn2c1

BDBM677857

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2ncccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677858

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)c2ncccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677859

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2cc(F)ccc2F)c2c3cn[nH]c3nn2c1

BDBM677860

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(C)C)c2c3cn[nH]c3nn2c1

BDBM677861

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2ccccn2)c2c3cn[nH]c3nn2c1 |r|

BDBM677862

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)S(=O)(=O)CC(C)C)c2c3cn[nH]c3nn2c1

BDBM677863

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)Cc2ccccc2)c2c3cn[nH]c3nn2c1

BDBM677864

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)C(=O)NCC(C)C)c2c3cn[nH]c3nn2c1

BDBM677865

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCC3)(CC2)C(=O)NCC(C)C)c2c3cn[nH]c3nn2c1

BDBM677866

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCCC3)(CC2)C(=O)NCC(C)C)c2c3cn[nH]c3nn2c1

BDBM677847

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677848

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677849

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(CCC3)C(F)(F)F)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677850

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3Cl)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677867

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3Cl)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677851

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(F)cccc3Cl)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677868

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3C(F)(F)F)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677852

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3C)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677869

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(C)cccc3Cl)[C@@H](N)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677870

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3ncccc3Cl)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677871

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3c(F)cccc3Cl)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677872

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c3cn[nH]c3nn2c1

BDBM677873

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2nc(C)ccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677874

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(F)ccc(F)c2F)c2c3cn[nH]c3nn2c1

BDBM677875

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677877

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)C(=O)NCC(C)C)c2c3cn[nH]c3nn2c1

BDBM677853

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)(C)C)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677878

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C(C)C(C)C)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677879

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3cc(F)ccc3Cl)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677880

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)NC(C)C)c2c3cn[nH]c3nn2c1

BDBM677881

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CNS(=O)(=O)c3ccccc3)CC2)c2c3cn[nH]c3nn2c1

BDBM677882

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c3cn[nH]c3nn2c1

BDBM677883

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(C)nn2)c2c3cn[nH]c3nn2c1

BDBM677884

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NS(=O)(=O)c3c(F)cccc3Cl)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677885

CCOc1cc(-c2ccc(nc2)N2CC3COCC(C2)N3Cc2ccc(OC)nc2)c2c3cn[nH]c3nn2c1

BDBM677886

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3CN(C[C@@H]3C2)C(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1 |r|

BDBM677887

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(nc2)S(C)(=O)=O)c2c3cn[nH]c3nn2c1

BDBM677888

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2cc(F)ccc2F)c2c3cn[nH]c3nn2c1

BDBM677889

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3CN(Cc4ccc(OC)nc4)C[C@@H]3C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677890

CCOc1cc(-c2ccc(nc2)N2CC3CCC(C2)N3C(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677891

CCOc1cc(-c2ccc(nc2)N2CC3CCC(C2)N3Cc2ccc(OC)nc2)c2c3cn[nH]c3nn2c1

BDBM677892

CCOc1cc(-c2ccc(nc2)N2C3CCC2CN(C3)C(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677893

CCOc1cc(-c2ccc(nc2)N2C3CCC2CN(Cc2ccc(OC)nc2)C3)c2c3cn[nH]c3nn2c1

BDBM677894

CCOc1cc(-c2ccc(nc2)N2CC3CCC2CN3C(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677895

CCOc1cc(-c2ccc(nc2)N2CC3CCC2CN3Cc2ccc(OC)nc2)c2c3cn[nH]c3nn2c1

BDBM677896

CCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)C3(CC3)C2)c2c3cn[nH]c3nn2c1

BDBM677897

CCOc1cc(-c2ccc(nc2)N2CC3COCC(C2)N3C(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677898

CCOc1cc(-c2ccc(nc2)N2C[C@H]3[C@@H](C2)[C@@H]3NC(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1 |r|

BDBM677899

CCOc1cc(-c2ccc(nc2)N2C[C@H]3[C@@H](C2)[C@H]3NC(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1 |r|

BDBM677900

CCOc1cc(-c2ccc(nc2)N2C[C@H]3[C@@H](C2)[C@H]3NCc2ccc(OC)nc2)c2c3cn[nH]c3nn2c1 |r|

BDBM677901

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C[C@@H]3C2)NC(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1 |r|

BDBM677902

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@@H](C[C@@H]3C2)NC(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1 |r|

BDBM677903

CCOc1cc(-c2ccc(nc2)N2C[C@H]3[C@@H](C2)C2CCC3N2C(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1 |r|

BDBM677904

CCOc1cc(-c2ccc(nc2)N2C[C@H]3[C@H](CNC(=O)c4c(F)cccc4Cl)[C@H]3C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677905

CCOc1cc(-c2ccc(nc2)N2CC3(C2)CCCN3Cc2ccc(OC)nc2)c2c3cn[nH]c3nn2c1

BDBM677906

CCOc1cc(-c2ccc(nc2)N2CC3(C2)CCN(C3)C(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677907

CCOc1cc(-c2ccc(nc2)N2CC3(C2)CCCN(C3)C(=O)c2c(F)cccc2Cl)c2c3cn[nH]c3nn2c1

BDBM677908

CCOc1cc(-c2ccc(nc2)N2CCC3(CCN3C(=O)c3c(F)cccc3Cl)CC2)c2c3cn[nH]c3nn2c1

BDBM677909

CCOc1cc(-c2ccc(nc2)N2CCC3(CCCN3Cc3ccc(OC)nc3)CC2)c2c3cn[nH]c3nn2c1

BDBM677910

CCOc1cc(-c2ccc(nc2)N2CCC3(CCN(C3)C(=O)c3c(F)cccc3Cl)CC2)c2c3cn[nH]c3nn2c1

BDBM677911

CCOc1cc(-c2ccc(nc2)N2CCC3(CCCN(C3)C(=O)c3c(F)cccc3Cl)CC2)c2c3cn[nH]c3nn2c1

BDBM677912

CCOc1cc(-c2ccc(nc2)N2CCCC3(CCN(Cc4ccc(OC)nc4)CC3)C2)c2c3cn[nH]c3nn2c1

BDBM677913

CCOc1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)c3c(F)cccc3Cl)C2)c2c3cn[nH]c3nn2c1

BDBM677914

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC#C)cn3nc4[nH]ncc4c23)cn1

BDBM677915

COC(=O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c3cn[nH]c3nn2c1

BDBM677916

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NCc2ccc(OC)nc2)c2c3cn[nH]c3nn2c1

BDBM677917

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(F)cccc3F)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677918

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)c2c(F)cccc2F)c2c3cn[nH]c3nn2c1

BDBM677919

COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c3cn[nH]c3nn2c1

BDBM677920

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(cn3nc4[nH]ncc4c23)P(C)(C)=O)cn1

BDBM677921

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(cn3nc4[nH]ncc4c23)C(O)=O)cn1

BDBM677923

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC(=O)C=C)cn3nc4[nH]ncc4c23)cn1

BDBM677924

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(cn3nc4[nH]ncc4c23)C#N)cn1

BDBM677925

CCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)C(CN(C)C)C2)c2c3cn[nH]c3nn2c1

BDBM677926

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c3c(n[nH]c3nn2c1)C#N

BDBM677927

CCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)C(CO)C2)c2c3cn[nH]c3nn2c1

BDBM677928

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)C=C)c2c3cn[nH]c3nn2c1

BDBM677929

CCOc1cc([C@H]2CC[C@](CC2)(OC)C(=O)N[C@@H](C)c2ccc(nc2)-n2cc(F)cn2)c2c3cn[nH]c3nn2c1 |r,wU:9.14,wD:9.12,17.18,6.5,(-9.77,-4.02,;-8.44,-3.25,;-8.44,-1.71,;-7.11,-.94,;-5.77,-1.71,;-4.44,-.94,;-3.11,-1.71,;-3.11,-3.25,;-1.77,-4.02,;-.44,-3.25,;-.44,-1.71,;-1.77,-.94,;.29,-4.61,;-.53,-5.92,;1.1,-3.31,;1.82,-4.67,;1.81,-1.83,;3.35,-1.83,;4.13,-3.16,;4.14,-.5,;3.37,.83,;4.14,2.16,;5.68,2.16,;6.45,.83,;5.68,-.5,;6.47,3.48,;8,3.64,;8.32,5.15,;9.77,5.67,;6.99,5.92,;5.85,4.89,;-4.44,.6,;-3.29,1.63,;-1.76,1.79,;-1.44,3.3,;-2.78,4.07,;-3.92,3.04,;-5.45,2.87,;-5.77,1.37,;-7.11,.6,)|

BDBM677930

O[C@@H]1CN(CC[C@@H]1NC(=O)c1c(F)cccc1F)c1ccc(cn1)-c1cc(OCCF)cn2nc3[nH]ncc3c12 |r|

BDBM677931

O[C@@H]1CN(CC[C@@H]1NC(=O)c1c(F)cccc1F)c1ccc(cn1)-c1cc(OCC(F)F)cn2nc3[nH]ncc3c12 |r|

BDBM677932

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NS(=O)(=O)c3c(F)cccc3F)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677933

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3F)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677934

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(F)ccc(F)c3F)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677935

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(F)cccc3Cl)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677936

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3Cl)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677937

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3C)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677938

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(C)cccc3Cl)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677939

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ccccc3C(F)(F)F)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677940

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ccccc3C#N)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677941

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(CCC3)C(F)(F)F)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677942

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(F)CC3)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677943

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C(C)C(C)C)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677944

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3C(F)(F)F)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677945

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncc(F)cc3Cl)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677946

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3F)[C@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677948

O[C@@H]1CN(CC[C@@H]1NC(=O)c1c(F)cccc1Cl)c1ccc(cn1)-c1cc(OCC(F)F)cn2nc3[nH]ncc3c12 |r|

BDBM677949

O[C@@H]1CN(CC[C@@H]1NC(=O)c1cc(F)ccc1Cl)c1ccc(cn1)-c1cc(OCC(F)F)cn2nc3[nH]ncc3c12 |r|

BDBM677950

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(F)cccc3F)[C@@H](O)C2)c2c3cn[nH]c3nn2c1 |r|

BDBM677951

O[C@H]1CN(CC[C@@H]1NC(=O)c1c(F)cccc1F)c1ccc(cn1)-c1cc(OCCF)cn2nc3[nH]ncc3c12 |r|

BDBM677952

O[C@H]1CN(CC[C@@H]1NC(=O)c1c(F)cccc1F)c1ccc(cn1)-c1cc(OCC(F)F)cn2nc3[nH]ncc3c12 |r|

BDBM677953

COc7ccc(CN1C6CC1CN(c5ccc(c3cc(OCC(F)(F)F)cn4nc2[nH]ncc2c34)cn5)C6)cn7

BDBM50021574

COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC

BDBM753574

COc8ccc(CN1C7CC1CN(c6ccc(c4cc(OCc2ccccc2)cn5nc3[nH]ncc3c45)cn6)C7)cn8

BDBM753575

N#Cc1cc(-c2ccc(N3CC4CC(C3)N4Cc3ccc(OC)nc3)nc2)c2c3cn[nH]c3nn2c1

BDBM753511

COCCOc1cc(-c2ccc(N3CC4CC(C3)N4Cc3ccc(OC)nc3)nc2)c2c3c(nn2c1)CN=C3

BDBM753576

COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCCO)cn5nc6[nH]ncc6c45)cn2)C3)cn1

BDBM753577

CCCCOc1cc(-c2ccc(N3CC4CC(C3)N4Cc3ccc(OC)nc3)nc2)c2c3cn[nH]c3nn2c1

BDBM753517

COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCCCF)cn5nc6[nH]ncc6c45)cn2)C3)cn1

BDBM753578

COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCCCCF)cn5nc6[nH]ncc6c45)cn2)C3)cn1

BDBM753579

COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCCCl)cn5nc6[nH]ncc6c45)cn2)C3)cn1

BDBM753580

COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCCBr)cn5nc6[nH]ncc6c45)cn2)C3)cn1

BDBM753571

COc1ccc(CN2C3CC2CN(c2cnc(-c4cc(OCCF)cn5nc6[nH]ncc6c45)cn2)C3)cn1

BDBM753581

CCN(CC)C(=O)N1CCN(c2ccc(-c3cc(OCCF)cn4nc5c(c34)C=NC5)cn2)CC1

BDBM753582

O=C(Cc1ccccn1)N1CCN(c2ccc(-c3cc(OCCF)cn4nc5[nH]ncc5c34)cn2)CC1

BDBM753583

O=C([C@H](O)c1ccccc1)N1CCN(c2ccc(-c3cc(OCCF)cn4nc5[nH]ncc5c34)cn2)CC1

BDBM753584

CO[C@@H](C(=O)N1CCN(c2ccc(-c3cc(OCCF)cn4nc5[nH]ncc5c34)cn2)CC1)c1ccccc1

BDBM753585

COc1ccc(C(=O)N2CCN(c3ccc(-c4cc(OCCF)cn5nc6[nH]ncc6c45)cn3)CC2)cn1

BDBM753586

COc1cc(-c2cnc(N3CC4CC(C3)N4Cc3ccc(OC)nc3)cn2)c2c3c(nn2c1)CN=C3

BDBM753587

COc1ccc(CN2C3CC2CN(c2cnc(-c4cc(OCC(F)F)cn5nc6[nH]ncc6c45)cn2)C3)cn1

BDBM753588

N#CCOc1cc(-c2ccc(N3CC4CC(C3)N4Cc3ccc(OC)nc3)nc2)c2c3cn[nH]c3nn2c1

BDBM753524

COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCCOC(F)F)cn5nc6[nH]ncc6c45)cn2)C3)cn1

BDBM753528

COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCCF)cn5nc6[nH]ncc6c45)cn2)C3)cn1

BDBM753566

COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCC(F)F)cn5nc6[nH]ncc6c45)cn2)C3)cn1

BDBM753568

CCCOc1cc(-c2ccc(N3CC4CC(C3)N4Cc3ccc(OC)nc3)nc2)c2c3cn[nH]c3nn2c1

BDBM753569

COc1ccc(CN2C3CC2CN(c2ccc(-c4cc(OCC(C)C)cn5nc6[nH]ncc6c45)cn2)C3)cn1