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Found 206 with Last Name = 'medek' and Initial = 'a'
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615196(3-[2-(4-cyanophenyl)-1H-indol-3-yl]-N-[(3S,4R)-4-h...)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615197(US20230271945, Compound 117)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615198(US20230271945, Compound 118)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615198(US20230271945, Compound 118)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615200(US20230271945, Compound 120)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615200(US20230271945, Compound 120)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM50547880(CHEMBL4789274 | US20230271945, Compound 121)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM50547880(CHEMBL4789274 | US20230271945, Compound 121)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615202(US20230271945, Compound 122)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615202(US20230271945, Compound 122)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615203(US20230271945, Compound 123)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615203(US20230271945, Compound 123)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615204(US20230271945, Compound 124)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615204(US20230271945, Compound 124)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615205(US20230271945, Compound 125)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615205(US20230271945, Compound 125)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615206(US20230271945, Compound 126)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615206(US20230271945, Compound 126)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615208(3-[2-(4-chlorophenyl)-1H-indol-3-yl]-N-[(3S,4R)-4-...)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615208(3-[2-(4-chlorophenyl)-1H-indol-3-yl]-N-[(3S,4R)-4-...)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615209(3-[2-(3,4-difluorophenyl)-1H-indol-3-yl]-N-[(3S,4R...)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615209(3-[2-(3,4-difluorophenyl)-1H-indol-3-yl]-N-[(3S,4R...)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615210(2-[[2-(4-fluorophenyl)-1H-indol-3-yl]sulfanyl]-N-[...)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615124(3-[2-(4-bromophenyl)-5-methyl-1H-indol-3-yl]-N-[(3...)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615124(3-[2-(4-bromophenyl)-5-methyl-1H-indol-3-yl]-N-[(3...)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615125(3-(5-chloro-2-phenyl-1H-indol-3-yl)-N-[(3S,4R)-4-h...)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615125(3-(5-chloro-2-phenyl-1H-indol-3-yl)-N-[(3S,4R)-4-h...)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615126(3-[5-chloro-2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(...)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615127(US20230271945, Compound 46)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615127(US20230271945, Compound 46)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615128(US20230271945, Compound 47)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615128(US20230271945, Compound 47)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615129(US20230271945, Compound 48)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615129(US20230271945, Compound 48)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615132(US20230271945, Compound 51)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615132(US20230271945, Compound 51)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615133(US20230271945, Compound 52)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615133(US20230271945, Compound 52)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615139(US20230271945, Compound 58)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615139(US20230271945, Compound 58)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615140(US20230271945, Compound 59)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615140(US20230271945, Compound 59)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM50547878(CHEMBL4752052 | US20230271945, Compound 61)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM50547878(CHEMBL4752052 | US20230271945, Compound 61)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615143(N-[(3S,4R)-4-hydroxy-2-oxo-pyrrolidin-3-yl]-3-(2-p...)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615144(US20230271945, Compound 63)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615150(US20230271945, Compound 69)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615151(US20230271945, Compound 70)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615151(US20230271945, Compound 70)
Affinity DataIC50:  600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApolipoprotein L1(Homo sapiens)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615152(US20230271945, Compound 71)
Affinity DataIC50:  600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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