Found 632 with Last Name = 'paul' and Initial = 'a' 
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of recombinant matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
Affinity DataKi: 1.70nM ΔG°: -49.6kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nM ΔG°: -49.3kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 4.80nM ΔG°: -47.0kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 5.80nM ΔG°: -46.5kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Inhibition of recombinant matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nM ΔG°: -46.2kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 9.80nM ΔG°: -45.3kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 20nM ΔG°: -43.5kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of recombinant matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Affinity DataKi: 23.4nMAssay Description:Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 48nM ΔG°: -41.4kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 62nM ΔG°: -40.7kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of recombinant matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
Affinity DataKi: 84nM ΔG°: -40.0kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
Affinity DataKi: 108nM ΔG°: -39.4kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 135nMAssay Description:Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 169nM ΔG°: -38.3kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 169nM ΔG°: -38.3kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 219nMAssay Description:Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 287nM ΔG°: -37.0kJ/molepH: 8.0 T: 2°CAssay Description:The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Displacement of [125I]cyanopindolol from human cloned beta-1 adrenergic receptor expressed in Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 610nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 650nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
Affinity DataKi: 678nMAssay Description:Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
Affinity DataKi: 902nMAssay Description:Displacement of [3H]PGE2 from human EP4R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
Affinity DataKi: 1.49E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
Affinity DataKi: 1.59E+3nMAssay Description:Displacement of [125I]cyanopindolol from human cloned beta-2 adrenergic receptor expressed in Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
Affinity DataKi: 1.66E+3nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
