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Found 22 with Last Name = 'phelan' and Initial = 'a'
LigandPNGBDBM50356930(CHEMBL1914475)
Affinity DataIC50:  25nMAssay Description:Inhibition of PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50189744((Z)-5-((5-(4-fluoro-2-hydroxyphenyl)furan-2-yl)met...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant human PI3Kgamma by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356930(CHEMBL1914475)
Affinity DataIC50:  34nMAssay Description:Inhibition of recombinant human PI3Kgamma by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356940(CHEMBL1916047)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant human PI3Kgamma by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356930(CHEMBL1914475)
Affinity DataIC50:  760nMAssay Description:Inhibition of PI3Kgamma in human neutrophils assessed as inhibition of fMLP-stimulated superoxide productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356939(CHEMBL1916046)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of recombinant human PI3Kgamma by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356937(CHEMBL1728139)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of recombinant human PI3Kgamma assessed as depletion of ATP by kinase-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356931(CHEMBL1916042)
Affinity DataIC50:  1.56E+5nMAssay Description:Inhibition of recombinant human PI3Kgamma assessed as depletion of ATP by kinase-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356932(CHEMBL1889525 | cid_40237)
Affinity DataIC50:  3.80E+5nMAssay Description:Inhibition of recombinant human PI3Kgamma assessed as depletion of ATP by kinase-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356935(CHEMBL1916044)
Affinity DataIC50:  3.95E+5nMAssay Description:Inhibition of recombinant human PI3Kgamma assessed as depletion of ATP by kinase-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356936(CHEMBL1916045)
Affinity DataIC50:  7.73E+5nMAssay Description:Inhibition of recombinant human PI3Kgamma assessed as depletion of ATP by kinase-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356938(CHEMBL1916048)
Affinity DataIC50:  9.15E+5nMAssay Description:Inhibition of recombinant human PI3Kgamma assessed as depletion of ATP by kinase-glo luciferase assayMore data for this Ligand-Target Pair
LigandPNGBDBM50356933(CHEMBL1887078)
Affinity DataIC50: >1.60E+6nMAssay Description:Inhibition of recombinant human PI3Kgamma assessed as depletion of ATP by kinase-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356934(CHEMBL1916043)
Affinity DataIC50: >1.67E+6nMAssay Description:Inhibition of recombinant human PI3Kgamma assessed as depletion of ATP by kinase-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384056(CHEMBL2032449)
Affinity DataEC50:  5nMAssay Description:Agonist activity at recombinant kappa opioid receptor expressed in human U2OS cells coexpressing beta arrestin/EA complex assessed as beta arrestin r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384057(CHEMBL2032450)
Affinity DataEC50:  1.48E+3nMAssay Description:Agonist activity at recombinant kappa opioid receptor expressed in human U2OS cells coexpressing beta arrestin/EA complex assessed as beta arrestin r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384058(CHEMBL2032451)
Affinity DataEC50:  176nMAssay Description:Agonist activity at recombinant kappa opioid receptor expressed in human U2OS cells coexpressing beta arrestin/EA complex assessed as beta arrestin r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384054(CHEMBL2032447)
Affinity DataEC50:  0.220nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig illeum assessed as electric field-stimulated responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384059(CHEMBL2032452)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig illeum assessed as electric field-stimulated responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384054(CHEMBL2032447)
Affinity DataEC50:  3nMAssay Description:Agonist activity at recombinant kappa opioid receptor expressed in human U2OS cells coexpressing beta arrestin/EA complex assessed as beta arrestin r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384053(CHEMBL2032453)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig illeum assessed as electric field-stimulated responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384055(CHEMBL2032448)
Affinity DataEC50:  3nMAssay Description:Agonist activity at recombinant kappa opioid receptor expressed in human U2OS cells coexpressing beta arrestin/EA complex assessed as beta arrestin r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed