BindingDB PrimarySearch

Found 91 with Last Name = 'mosig' and Initial = 'as'

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

IC50: 40nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576502(CHEMBL3092679)

IC50: 50nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576500(CHEMBL4847874)

IC50: 50nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of A23187 and measured af...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50527521(CHEMBL4463788)

IC50: 60nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576496(CHEMBL4876438)

IC50: 70nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576481(CHEMBL2151600)

IC50: 80nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576507(CHEMBL4856987)

IC50: 90nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576501(CHEMBL4865488)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576522(CHEMBL4849927)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576501(CHEMBL4865488)

IC50: 100nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576502(CHEMBL3092679)

IC50: 110nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576500(CHEMBL4847874)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576512(CHEMBL4872620)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576514(CHEMBL4868153)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576513(CHEMBL4869687)

IC50: 120nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50555730(CHEMBL4747347)

IC50: 150nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576503(CHEMBL3092680)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576492(CHEMBL4853392)

IC50: 170nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576509(CHEMBL4863843)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576511(CHEMBL4852521)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576510(CHEMBL4856621)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576494(CHEMBL4866333)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576504(CHEMBL4860001)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576484(CHEMBL4858254)

IC50: 180nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576524(CHEMBL4875395)

IC50: 210nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576520(CHEMBL4859499)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576518(CHEMBL4848638)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576481(CHEMBL2151600)

IC50: 270nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576483(CHEMBL4869499)

IC50: 300nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576515(CHEMBL4858051)

IC50: 310nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50555730(CHEMBL4747347)

IC50: 310nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50527521(CHEMBL4463788)

IC50: 350nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576506(CHEMBL4876100)

IC50: 380nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576522(CHEMBL4849927)

IC50: 390nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50555729(CHEMBL4761835)

IC50: 400nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576503(CHEMBL3092680)

IC50: 430nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576486(CHEMBL4859324)

IC50: 440nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576485(CHEMBL4858451)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576507(CHEMBL4856987)

IC50: 450nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576486(CHEMBL4859324)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576487(CHEMBL4858148)

IC50: 470nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576519(CHEMBL4878678)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576483(CHEMBL4869499)

IC50: 490nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576524(CHEMBL4875395)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576500(CHEMBL4847874)

IC50: 500nMAssay Description:Inhibition of 5-LOX in LPS-stimulated human monocytes assessed as reduction in 5-LOX product formation prestimulated with LPS for 24 hrs followed by ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576481(CHEMBL2151600)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50555729(CHEMBL4761835)

IC50: 560nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576492(CHEMBL4853392)

IC50: 610nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576517(CHEMBL4858438)

IC50: 630nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL

BDBM50576484(CHEMBL4858254)

IC50: 630nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid

Details Article PubMed

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