Report error Found 639 with Last Name = 'frett' and Initial = 'b'
TargetVascular endothelial growth factor receptor 2(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of human recombinant full length VEGFR2 in presence of ATP by alphascreen assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal stripsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant RET V804L (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of FLT3 (unknown origin) by kinase hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.316nMAssay Description:Inhibition of recombinant human full-length His-tagged Aurora B expressed in baculovirus expression system using 5-FAM-LRRASLG-CONH2 as substrate pre...More data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.326nMAssay Description:Inhibition of recombinant human full-length His-tagged Aurora B expressed in baculovirus expression system using 5-FAM-LRRASLG-CONH2 as substrate pre...More data for this Ligand-Target Pair
TargetCoiled-coil domain-containing protein 6(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibition of CCDC6-RET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.336nMAssay Description:Inhibition of recombinant human full-length His-tagged Aurora B expressed in baculovirus expression system using 5-FAM-LRRASLG-CONH2 as substrate pre...More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of wildtype RET (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform methodMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant RET M918T (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform methodMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of wildtype RET (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetCoiled-coil domain-containing protein 6(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant CCDC6-RET (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform methodMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret /Nuclear receptor coactivator 4 fusion protein(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Inhibition of NCOA4-RET (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.420nMAssay Description:Inhibition of recombinant RET V804L (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform methodMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BCR-ABL (unknown origin) by kinase hotspot assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:Inhibition of BTK (unknown origin) after 60 mins by FRET assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Irreversible inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.670nMAssay Description:Inhibition of RET isoform 9 C634W mutant in human TT cells assessed as reduction in cell proliferation supplemented with fresh medium containing comp...More data for this Ligand-Target Pair
TargetCoiled-coil domain-containing protein 6(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.670nMAssay Description:Inhibition of CCDC6/RET in human LC2/ad cells assessed as reduction in cell proliferation supplemented with fresh medium containing compound for ever...More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.670nMAssay Description:Inhibition of RET isoform 9 M918T mutant in human MZ-CRC-1 cells assessed as reduction in cell proliferation supplemented with fresh medium containin...More data for this Ligand-Target Pair
TargetCoiled-coil domain-containing protein 6(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.670nMAssay Description:Inhibition of CCDC6/RET in human TPC1 cells assessed as reduction in cell proliferation supplemented with fresh medium containing compound for every ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant RET M918T (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.730nMAssay Description:Binding affinity towards rat beta adrenergic receptor from heart membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.850nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.980nMAssay Description:Inhibition of TRKA G667C mutant (unknown origin) using poly-EAY peptide as substrate in presence of gamma-33ATP by LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal stripsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: >1nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Human)
University of Arkansas For Medical Sciences
Curated by ChEMBL
University of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: >1nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair