BindingDB PrimarySearch_ki

Found 197 with Last Name = 'klebl' and Initial = 'b'

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50106301(CHEMBL3598140)

IC50: 7nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
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3D Structure (crystal)

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595941(CHEMBL5200206)

IC50: 7.40nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595938(CHEMBL5197292)

IC50: 12nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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3D Structure (crystal)

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50106301(CHEMBL3598140)

IC50: 13nMAssay Description:Allosteric inverse agonist activity at C-terminal His-tagged RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair

PDB Reactome pathway
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3D Structure (crystal)

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595941(CHEMBL5200206)

IC50: 20nMAssay Description:Allosteric inverse agonist activity at C-terminal His-tagged RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595938(CHEMBL5197292)

IC50: 31nMAssay Description:Allosteric inverse agonist activity at C-terminal His-tagged RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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3D Structure (crystal)

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595946(CHEMBL5180168)

IC50: 33nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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3D Structure (crystal)

Ribosomal protein S6 kinase beta-2(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL

PNG

BDBM50168247(2,3-Di-thiophen-2-yl-benzo[g]quinoxaline-7-carboxy...)

IC50: 40nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
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Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595945(CHEMBL5178739)

IC50: 46nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
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3D Structure (crystal)

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595944(CHEMBL5177875)

IC50: 74nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
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3D Structure (crystal)

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50519883(CHEMBL4522217)

IC50: 100nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
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Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595946(CHEMBL5180168)

IC50: 110nMAssay Description:Allosteric inverse agonist activity at C-terminal His-tagged RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair

PDB Reactome pathway
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3D Structure (crystal)

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595945(CHEMBL5178739)

IC50: 140nMAssay Description:Allosteric inverse agonist activity at C-terminal His-tagged RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair

PDB Reactome pathway
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3D Structure (crystal)

Serine/threonine-protein kinase pim-1(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 200nMAssay Description:Inhibition of PIM1 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595944(CHEMBL5177875)

IC50: 220nMAssay Description:Allosteric inverse agonist activity at C-terminal His-tagged RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair

PDB Reactome pathway
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3D Structure (crystal)

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50519883(CHEMBL4522217)

IC50: 270nMAssay Description:Allosteric inverse agonist activity at C-terminal His-tagged RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair

PDB Reactome pathway
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Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595942(CHEMBL5177120)

IC50: 290nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Cyclin-dependent kinase 9(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509371(CHEMBL4521241)

IC50: 300nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595942(CHEMBL5177120)

IC50: 490nMAssay Description:Allosteric inverse agonist activity at C-terminal His-tagged RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Mitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509370(CHEMBL4446434)

IC50: 500nMAssay Description:Inhibition of MLK3 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase 17B(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 500nMAssay Description:Inhibition of DRAK2 (unknown origin) expressed in HEK293 cells by NanoLuc-luciferase reporter based intracellular ATP competitiveness assayMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Mitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 600nMAssay Description:Inhibition of GCK (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Mitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 600nMAssay Description:Inhibition of MLK3 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 600nMAssay Description:Inhibition of MLK1 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
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Ribosomal protein S6 kinase beta-2(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL

PNG

BDBM50168248(CHEMBL192909 | {5-[3-(4-Carboxymethyl-thiophen-2-y...)

IC50: 640nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
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Aurora kinase B(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 800nMAssay Description:Inhibition of Aurora B (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Ribosomal protein S6 kinase beta-2(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL

PNG

BDBM50168244(4-(5-{3-[5-(3-Carboxy-propyl)-thiophen-2-yl]-benzo...)

IC50: 820nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Ribosomal protein S6 kinase beta-2(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL

PNG

BDBM50168242(3-(5-{3-[5-(2-Carboxy-ethyl)-thiophen-2-yl]-benzo[...)

IC50: 870nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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Mitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509370(CHEMBL4446434)

IC50: 900nMAssay Description:Inhibition of MLK1 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Aurora kinase B(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509370(CHEMBL4446434)

IC50: 900nMAssay Description:Inhibition of Aurora B (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Serine/threonine-protein kinase pim-1(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509370(CHEMBL4446434)

IC50: 900nMAssay Description:Inhibition of PIM1 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Ribosomal protein S6 kinase beta-2(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL

PNG

BDBM50168241(6,7-Di-thiophen-2-yl-2,3-dihydro-1,4-dioxa-5,8-dia...)

IC50: 950nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Mitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509370(CHEMBL4446434)

IC50: 1.00E+3nMAssay Description:Inhibition of TAK1 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Mitogen-activated protein kinase 15(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 1.00E+3nMAssay Description:Inhibition of ERK8 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

Details Article PubMed

Receptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 1.10E+3nMAssay Description:Inhibition of RIPK2 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Ribosomal protein S6 kinase beta-2(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL

PNG

BDBM50168239(7,8-Dimethoxy-2,3-di-thiophen-2-yl-pyrazino[2,3-b]...)

IC50: 1.14E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid

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Mitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509370(CHEMBL4446434)

IC50: 1.20E+3nMAssay Description:Inhibition of GCK (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 1.20E+3nMAssay Description:Inhibition of SIK3 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Mitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 1.20E+3nMAssay Description:Inhibition of TAK1 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Ribosomal protein S6 kinase beta-2(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL

PNG

BDBM50168236(CHEMBL193162 | {5-[3-(5-Carboxymethyl-thiophen-2-y...)

IC50: 1.28E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Ribosomal protein S6 kinase beta-2(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL

PNG

BDBM50168235(2,3-Di-thiophen-2-yl-benzo[g]quinoxaline | CHEMBL3...)

IC50: 1.36E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595943(CHEMBL5189438)

IC50: 1.50E+3nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Serine/threonine-protein kinase pim-3(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 1.80E+3nMAssay Description:Inhibition of PIM3 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595948(CHEMBL5205628)

IC50: 1.80E+3nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595947(CHEMBL5182239)

IC50: 1.90E+3nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 2.30E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595939(CHEMBL5209370)

IC50: 2.50E+3nMAssay Description:Displacement of Alexa flour647-labeled MRL-871 from RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cell...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Nuclear receptor ROR-gamma(Homo sapiens (Human))
Technische Universiteit Eindhoven

Curated by ChEMBL

PNG

BDBM50595948(CHEMBL5205628)

IC50: 2.90E+3nMAssay Description:Allosteric inverse agonist activity at C-terminal His-tagged RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Serine/threonine-protein kinase 17A(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509365(CHEMBL4564337)

IC50: 3.00E+3nMAssay Description:Inhibition of DRAK1 (unknown origin) expressed in HEK293 cells by NanoLuc-luciferase reporter based intracellular ATP competitiveness assayMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Serine/threonine-protein kinase 17B(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL

PNG

BDBM50509368(CHEMBL4475097)

IC50: 3.30E+3nMAssay Description:Inhibition of DRAK2 (unknown origin) expressed in HEK293 cells by NanoLuc-luciferase reporter based intracellular ATP competitiveness assayMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Displayed 1 to 50 (of 197 total ) | Next | Last >>

Filter my 197 hits

Targets 35▿
- Peroxisome proliferator-activated receptor gamma 26
- Nuclear receptor ROR-gamma 26
- Tyrosine-protein kinase receptor UFO 16
- Ribosomal protein S6 kinase beta-2 15
- Serine/threonine-protein kinase 17A 9
- Serine/threonine-protein kinase 17B 9
- Serine/threonine-protein kinase pim-3 7
- Serine/threonine-protein kinase pim-1 7
- Mitogen-activated protein kinase kinase kinase kinase 2 6
- Mitogen-activated protein kinase kinase kinase 9 6
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A 6
- Mitogen-activated protein kinase kinase kinase 7 6
- Mitogen-activated protein kinase 15 6
- Mitogen-activated protein kinase kinase kinase 11 6
- Aurora kinase B 6
- Serine/threonine-protein kinase pim-2 6
- Receptor-interacting serine/threonine-protein kinase 2 6
- Aurora kinase A 6
- Serine/threonine-protein kinase SIK3 6
- Receptor-type tyrosine-protein kinase FLT3 1
- Myosin light chain kinase family member 4 1
- Cyclin-G-associated kinase 1
- Interleukin-1 receptor-associated kinase 3 1
- Cyclin-dependent kinase 9 1
- Citron Rho-interacting kinase 1
- BMP-2-inducible protein kinase 1
- Tyrosine-protein kinase JAK1 1
- Serine/threonine-protein kinase 35 1
- Serine/threonine-protein kinase 36 1
- Serine/threonine-protein kinase DCLK3 1
- Serine/threonine-protein kinase RIO1 1
- Non-receptor tyrosine-protein kinase TYK2 1
- 1-phosphatidylinositol 3-phosphate 5-kinase 1
- Casein kinase I isoform epsilon 1
- Phosphatidylinositol 4-kinase beta 1
- ...
Publications 4▿
- J Med Chem 62: 10167-10181 (2019) 114
- J Med Chem 64: 9238-9258 (2021) 52
- US Patent US8999982 (2015) 16
- Bioorg Med Chem Lett 15: 3241-6 (2005) 15
Institutions 4▿
- Uit - The Arctic University of Norway 114
- Technische Universiteit Eindhoven 52
- Lead Discovery Center 16
- Semmelweis University 15
Affinity: 7 to 1.0E+5 nM▿
- IC50 165
- Kd 19
- EC50 13
- Affinity ≤ nM
Xtal structures: 5
Docked structures: 0
Catalog Cmpds: 8