Affinity DataIC50: 0.200nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.275nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.309nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.388nMAssay Description:Inhibition of recombinant human BACE2 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.481nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.555nMAssay Description:Inhibition of recombinant human BACE2 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.603nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.615nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.871nMAssay Description:Inhibition of recombinant human BACE2 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair