TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 104nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 164nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 186nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 189nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Affinity DataKi: 270nMAssay Description:Displacement of [3H]epibatadine from rat alpha3beta4 nAChR expressed in HEK293 cells after 2 hrs by betaplate counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 305nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 465nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 559nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 617nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Affinity DataKi: 794nMAssay Description:Displacement of [3H]epibatadine from rat alpha3beta4 nAChR expressed in HEK293 cells after 2 hrs by betaplate counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Affinity DataKi: 851nMAssay Description:Displacement of [3H]epibatadine from rat alpha3beta4 nAChR expressed in HEK293 cells after 2 hrs by betaplate counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 909nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Affinity DataKi: 980nMAssay Description:Displacement of [3H]epibatadine from rat alpha3beta4 nAChR expressed in HEK293 cells after 2 hrs by betaplate counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 984nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Affinity DataKi: 1.11E+3nMAssay Description:Displacement of [3H]epibatadine from rat alpha3beta4 nAChR expressed in HEK293 cells after 2 hrs by betaplate counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.29E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.64E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.83E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.93E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 0.560nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response measured after 5 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Torrey Pines Institute For Molecular Studies
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-evoked current by voltag...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair