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Found 63 with Last Name = 'morice' and Initial = 'c'
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bionomics

Curated by ChEMBL
LigandPNGBDBM50516168(CHEMBL4541269)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bionomics

Curated by ChEMBL
LigandPNGBDBM50516168(CHEMBL4541269)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bionomics

Curated by ChEMBL
LigandPNGBDBM50516168(CHEMBL4541269)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bionomics

Curated by ChEMBL
LigandPNGBDBM50516168(CHEMBL4541269)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bionomics

Curated by ChEMBL
LigandPNGBDBM50516168(CHEMBL4541269)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241545(CHEMBL4059644)
Affinity DataEC50:  1.27E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241546(CHEMBL4071024)
Affinity DataEC50:  240nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241547(CHEMBL4097178)
Affinity DataEC50:  130nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241548(CHEMBL4089473)
Affinity DataEC50:  280nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241549(CHEMBL4068295)
Affinity DataEC50:  860nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241550(CHEMBL4067271)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241551(CHEMBL4088412)
Affinity DataEC50:  2.47E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241552(CHEMBL4085101)
Affinity DataEC50:  90nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241554(CHEMBL4063474)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241555(CHEMBL4062968)
Affinity DataEC50:  160nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241556(CHEMBL4083118)
Affinity DataEC50:  1.74E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241557(CHEMBL4101095)
Affinity DataEC50:  3.01E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241559(CHEMBL4093353)
Affinity DataEC50:  9.84E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241560(CHEMBL4064041)
Affinity DataEC50:  750nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241561(CHEMBL4085608)
Affinity DataEC50:  1.01E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241562(CHEMBL4103895)
Affinity DataEC50:  1.72E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241563(CHEMBL4085967)
Affinity DataEC50:  1.39E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241564(CHEMBL4096136)
Affinity DataEC50:  690nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241565(CHEMBL4082167)
Affinity DataEC50:  106nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241566(CHEMBL4100168)
Affinity DataEC50:  25nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241567(CHEMBL4072094)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241568(CHEMBL4100586)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241569(CHEMBL4062426)
Affinity DataEC50:  165nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241573(CHEMBL4098112)
Affinity DataEC50:  1.71E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241574(CHEMBL4071064)
Affinity DataEC50:  2.34E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241575(CHEMBL4067875)
Affinity DataEC50:  46nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241575(CHEMBL4067875)
Affinity DataEC50:  70nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing chimeric G protein assessed as increase in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241575(CHEMBL4067875)
Affinity DataEC50:  27nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241576(CHEMBL4061970)
Affinity DataEC50:  53nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241577(CHEMBL4070594)
Affinity DataEC50:  4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241578(CHEMBL4105462)
Affinity DataEC50:  6nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241579(CHEMBL4081211)
Affinity DataEC50:  53nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50:  79nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50:  47nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241581(CHEMBL4079161)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241583(CHEMBL4067152)
Affinity DataEC50:  980nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241584(CHEMBL4072639)
Affinity DataEC50:  5.26E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241585(CHEMBL4077754)
Affinity DataEC50:  1.16E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50: >1.50E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing chimeric G protein assessed as increase in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241586(CHEMBL4095448)
Affinity DataEC50:  1.42E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241587(CHEMBL4082331)
Affinity DataEC50:  6.99E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241588(CHEMBL4098106)
Affinity DataEC50:  110nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241589(CHEMBL4097743)
Affinity DataEC50:  4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241590(CHEMBL4067872)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241591(CHEMBL4078081)
Affinity DataEC50:  1.63E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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