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Found 64 with Last Name = 'ramondetti' and Initial = 'c'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281169(CHEMBL4173846 | US20240034730, Compound 1)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281169(CHEMBL4173846 | US20240034730, Compound 1)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281169(CHEMBL4173846 | US20240034730, Compound 1)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant human N-terminal GST-fusion tagged DHODH expressed in Escherichia coli BL21 (DE3) using dihydroorotate as substrate at 50 u...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586377(CHEMBL5086254 | US20240034730, Compound 7)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant human N-terminal GST-fusion tagged DHODH expressed in Escherichia coli BL21 (DE3) using dihydroorotate as substrate at 50 u...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586381(CHEMBL5092556 | US20240034730, Compound 11)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586385(CHEMBL5090431 | US20240034730, Compound 15)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586386(CHEMBL5084878 | US20240034730, Compound 16)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586384(CHEMBL5088148 | US20240034730, Compound 14)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586374(CHEMBL5075870 | US20240034730, Compound 4)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586387(CHEMBL5090281 | US20240034730, Compound 17)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281170(CHEMBL4165923 | US20240034730, Compound 2)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281170(CHEMBL4165923 | US20240034730, Compound 2)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586375(CHEMBL5087682 | US20240034730, Compound 5)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM470454(N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxym...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586378(CHEMBL5079607 | US20240034730, Compound 8)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586383(CHEMBL5078949 | US20240034730, Compound 13)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50591141(CHEMBL5192490 | US20240034730, Compound 29)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as sub...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50235594(CHEMBL4105330)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50235596(CHEMBL4098306)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586380(CHEMBL5071607 | US20240034730, Compound 10)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50591156(CHEMBL5196292 | US20240034730, Compound 37)
Affinity DataIC50:  18nMAssay Description:Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281171(CHEMBL4177202 | US20240034730, Compound 3)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM119812(US20240034730, Compound ASLAN003 | US8691852, 20)
Affinity DataIC50:  35nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281171(CHEMBL4177202 | US20240034730, Compound 3)
Affinity DataIC50:  35nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50235589(CHEMBL4090575)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50235597(CHEMBL4088968)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281172(CHEMBL4165815 | US20240034730, Compound 18)
Affinity DataIC50:  43nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50235595(CHEMBL4081077)
Affinity DataIC50:  44nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50235593(CHEMBL4062046)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50235593(CHEMBL4062046)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281172(CHEMBL4165815 | US20240034730, Compound 18)
Affinity DataIC50:  50nMAssay Description:Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as sub...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50591155(CHEMBL5183718 | US20240034730, Compound 36)
Affinity DataIC50:  70nMAssay Description:Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586382(CHEMBL5079952 | US20240034730, Compound 12)
Affinity DataIC50:  72nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586376(CHEMBL5090397 | US20240034730, Compound 6)
Affinity DataIC50:  91nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50235590(CHEMBL4071260)
Affinity DataIC50:  108nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50591142(CHEMBL5209405 | US20240034730, Compound 30)
Affinity DataIC50:  114nMAssay Description:Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50586379(CHEMBL5080170 | US20240034730, Compound 9)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50363559(CHEMBL1946659)
Affinity DataIC50:  289nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataIC50:  388nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataIC50:  388nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50591140(CHEMBL5182435 | US20240034730, Compound 28)
Affinity DataIC50:  400nMAssay Description:Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281168(CHEMBL4167855 | US20240034730, Compound 27)
Affinity DataIC50:  480nMAssay Description:Inhibition of recombinant human N-terminal GST-fusion tagged DHODH expressed in Escherichia coli BL21 (DE3) using dihydroorotate as substrate at 50 u...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281168(CHEMBL4167855 | US20240034730, Compound 27)
Affinity DataIC50:  480nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50363564(CHEMBL1946851)
Affinity DataIC50:  599nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50281167(CHEMBL4175712 | US20240034730, Compound 38)
Affinity DataIC50:  760nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50235592(CHEMBL4061824)
Affinity DataIC50:  853nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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