Affinity DataIC50: 0.0320nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Binding affinity against Alpha-1 adrenergic receptor was determined using [3H]WB-4101 radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor was determined using [ [3H]spiperone radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of specific binding of [125I]-ET-1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of specific binding of [125I]-ET-1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Compound was evaluated for the antagonism at the Endothelin A receptor (G-protein coupled endothelin A)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Compound was evaluated for the antagonism at the Endothelin A receptor (G-protein coupled endothelin A)More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of specific binding of [125I]-ET-1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of specific binding of [125I]-ET-1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Compound was evaluated for the antagonism at the Endothelin B receptor in isolated rabbit jugularis veinMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of specific binding of [125I]-ET-1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Hoechst-Roussel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.More data for this Ligand-Target Pair