Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 117 with Last Name = 'tomassi' and Initial = 'cd'
TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310701(US10150763, Example A)
Affinity DataIC50:  1.76nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124206(US8748458, 14)
Affinity DataIC50:  2nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50:  3nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50:  9nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124205(US8748458, 11)
Affinity DataIC50:  13nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  16nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124202(US8748458, 8)
Affinity DataIC50:  19nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124201(US8748458, 5)
Affinity DataIC50:  22nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124203(US8748458, 9)
Affinity DataIC50:  31nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124204(US8748458, 10)
Affinity DataIC50:  57nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 3(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  62nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124206(US8748458, 14)
Affinity DataIC50:  64nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124198(US8748458, 1)
Affinity DataIC50:  68nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  71nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 9(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  90nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 11(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  112nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124202(US8748458, 8)
Affinity DataIC50:  116nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 5(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  123nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetPolyamine deacetylase HDAC10(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  126nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 9(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124206(US8748458, 14)
Affinity DataIC50:  145nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50:  151nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 7(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  157nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124198(US8748458, 1)
Affinity DataIC50:  158nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124204(US8748458, 10)
Affinity DataIC50:  182nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124205(US8748458, 11)
Affinity DataIC50:  182nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  212nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310701(US10150763, Example A)
Affinity DataIC50:  226nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124206(US8748458, 14)
Affinity DataIC50:  306nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 4(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50:  307nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 8(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  312nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 9(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50:  423nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124203(US8748458, 9)
Affinity DataIC50:  453nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50:  458nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 5(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50:  458nMT: 37°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310702(N-Hydroxy-7-[(3-methyl-1,2,4-thiadiazol-5-yl)(pyri...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310702(N-Hydroxy-7-[(3-methyl-1,2,4-thiadiazol-5-yl)(pyri...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310703(N-Hydroxy-7-((3-methyl-1,2,4-oxadiazol-5-yl)(pyrid...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310703(N-Hydroxy-7-((3-methyl-1,2,4-oxadiazol-5-yl)(pyrid...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310704(N-Hydroxy-8-((3-methyl-1,2,4-oxadiazol-5-yl)(pyrid...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310705(N-Hydroxy-7-((1-methyl-1H-pyrazol-3-yl)(pyridin-2-...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310705(N-Hydroxy-7-((1-methyl-1H-pyrazol-3-yl)(pyridin-2-...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310706(N-Hydroxy-8-((1-methyl-1H-pyrazol-3-yl)(pyridin-2-...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310707(N-Hydroxy-7-(pyridin-2-yl(1,3,4-thiadiazol-2-yl)am...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310707(N-Hydroxy-7-(pyridin-2-yl(1,3,4-thiadiazol-2-yl)am...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310708(N-Hydroxy-8-(pyridin-2-yl(1,3,4-thiadiazol-2-yl)am...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310709(N-Hydroxy-7-((5-methyl-1,3,4-thiadiazol-2-yl)(pyri...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310710(N-Hydroxy-8-((5-methyl-1,3,4-thiadiazol-2-yl)(pyri...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310711(7-(Benzo[d]oxazol-2-yl(pyridin-2-yl)amino)-N-hydro...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310711(7-(Benzo[d]oxazol-2-yl(pyridin-2-yl)amino)-N-hydro...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM310712(8-(Benzo[d]oxazol-2-yl(pyridin-2-yl)amino)-N-hydro...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Displayed 1 to 50 (of 117 total ) | Next | Last >>
Jump to: