Compile Data Set for Download or QSAR
maximum 50k data
Found 44 with Last Name = 'li' and Initial = 'ct'
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086083(1-[2-(3,4,5-Trimethoxy-phenyl)-pent-4-enoyl]-piper...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086090(1-[2-(3,4,5-Trimethoxy-phenyl)-butyryl]-piperidine...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086094(1-[2-(3,4,5-Trimethoxy-phenyl)-pentanoyl]-piperidi...)
Affinity DataIC50:  3.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086077(1-[3-Cyclopropyl-2-(3,4,5-trimethoxy-phenyl)-propi...)
Affinity DataIC50:  4.40nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132554((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086092(1-[3-Methyl-2-(3,4,5-trimethoxy-phenyl)-butyryl]-p...)
Affinity DataIC50:  5.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132550((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-propionyl]-...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132541((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132541((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132558((E)-(12S,13R,14S,17R,21S,23S,24R,25R,27R)-17-Ethyl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086078(1-(2-Cyclohexyl-2-phenyl-acetyl)-piperidine-2-carb...)
Affinity DataIC50:  12nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132542((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)
Affinity DataIC50:  15nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086082(1-[2-(3,4,5-Trimethoxy-phenyl)-pent-4-enoyl]-piper...)
Affinity DataIC50:  19nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086087(1-(3-Methyl-2-phenyl-butyryl)-piperidine-2-carboxy...)
Affinity DataIC50:  19nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132560((S)-1-((S)-2-Benzo[1,3]dioxol-5-yl-butyryl)-piperi...)
Affinity DataIC50:  26nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086085(1-(2-Phenyl-butyryl)-piperidine-2-carboxylic acid ...)
Affinity DataIC50:  40nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132544((S)-1-((S)-2-Phenyl-butyryl)-piperidine-2-carboxyl...)
Affinity DataIC50:  40nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132544((S)-1-((S)-2-Phenyl-butyryl)-piperidine-2-carboxyl...)
Affinity DataIC50:  40nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086075(1-[2-(3,4,5-Trimethoxy-phenyl)-pentanoyl]-piperidi...)
Affinity DataIC50:  43nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataIC50:  44nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132551(1-(1-Ethyl-propylcarbamoyl)-piperidine-2-carboxyli...)
Affinity DataIC50:  64nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086086(1-[3-Methyl-2-(3,4,5-trimethoxy-phenyl)-butyryl]-p...)
Affinity DataIC50:  65nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086079(1-(2-Cyclohexyl-2-phenyl-acetyl)-piperidine-2-carb...)
Affinity DataIC50:  66nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086080(1-(2-Phenyl-propionyl)-piperidine-2-carboxylic aci...)
Affinity DataIC50:  94nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086089(1-[3-Cyclopropyl-2-(3,4,5-trimethoxy-phenyl)-propi...)
Affinity DataIC50:  126nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086084(1-(2-Phenyl-butyryl)-piperidine-2-carboxylic acid ...)
Affinity DataIC50:  133nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086081(1-(3-Methyl-2-phenyl-butyryl)-piperidine-2-carboxy...)
Affinity DataIC50:  150nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086093(1-[2-(3,4,5-Trimethoxy-phenyl)-butyryl]-piperidine...)
Affinity DataIC50:  187nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086076(1-Diphenylacetyl-piperidine-2-carboxylic acid 1-(3...)
Affinity DataIC50:  273nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035703(CHEMBL3343903)
Affinity DataIC50:  510nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086091(1-(2-Phenyl-propionyl)-piperidine-2-carboxylic aci...)
Affinity DataIC50:  590nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035706(CHEMBL3343901)
Affinity DataIC50:  750nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035702(CHEMBL91933)
Affinity DataIC50:  890nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132547(1-Phenylacetyl-piperidine-2-carboxylic acid 1-(3-c...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132547(1-Phenylacetyl-piperidine-2-carboxylic acid 1-(3-c...)
Affinity DataIC50:  1.53E+3nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50132547(1-Phenylacetyl-piperidine-2-carboxylic acid 1-(3-c...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035704(CHEMBL3343902)
Affinity DataIC50:  2.39E+3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50229666((2S,3S)-2-((S)-1-((2S,3S)-2-amino-3-methylpentanoy...)
Affinity DataIC50:  2.53E+3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035708(CHEMBL3343899)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035707(CHEMBL3343900)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035705(CHEMBL90170)
Affinity DataIC50:  3.35E+3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50004558(7-(6-Hexylaminomethyl-2-oxa-bicyclo[2.2.1]hept-5-y...)
Affinity DataIC50:  2.50E+4nMAssay Description:Compound was evaluated for the competitive binding of [3H]-U-46,619 to washed washed human platelets at the Thromboxane A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035700(CHEMBL3343905)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035701(CHEMBL3343904)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed