Found 83 with Last Name = 'contractor' and Initial = 'd' TargetProtein kinase C alpha type(MOUSE)
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Binding affinity to mouse PKC-alpha assessed as inhibition constantMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(MOUSE)
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Binding affinity to mouse PKC-alpha assessed as inhibition constantMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of HDAC1 derived from human HeLa nuclear extract using COLOR DE LYS substrate by colorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of His-tagged recombinant human HDAC6 expressed in baculovirus infected insect cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of PDE9 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of PI3K-alpha (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of His-tagged recombinant human HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS-SIRT1 as substrate ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by ADP-Glo luminescent kinase assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human HDAC6 using HDAC substrate incubated for 30 mins by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human HDAC1 using HDAC substrate incubated for 30 mins by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of PI3K-gamma (unknown origin) by ADP-Glo luminescent kinase assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC1 (unknown origin) by microplate reader analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human HDAC2 using HDAC substrate incubated for 30 mins by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of PI3K-alpha (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of pan-HDAC (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of PI3K-beta (unknown origin) by ADP-Glo luminescent kinase assayMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of PDE9 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal GST-tagged full-length recombinant human PDE5A1 (1 to 875 residues) expressed in Sf9 insect cells using cGMP as substrate in...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of full-length recombinant human HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using fluorogenic substrate incubated for 30 min...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Displacement of fluorescent tracer from VDR (unknown origin) by fluorescence polarisation competition assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of LSD1 (unknown origin) using diMeK4H31-21 as substrate preincubated for 5 mins followed by substrate addition measured for 5 mins by abs...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of PDE9 (unknown origin)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of full-length recombinant human HDAC1 expressed in baculovirus infected Hi-5 insect cells using AcLys-Tyr-Lys(e-acetyl)-AMC as substrate ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of C-terminal 6xHis/FLAG-tagged full-length recombinant human HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic su...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 508nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 545nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 593nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
