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maximum 50k data
Found 38 with Last Name = 'huseby' and Initial = 'd'
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501358(CHEMBL3947604)
Affinity DataIC50:  6nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50:  8nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 decatenation incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
LigandPNGBDBM50568726(CHEMBL4854181)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: <10nMAssay Description:Inhibition of Pseudomonas aeruginosa DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
LigandPNGBDBM50613100(CHEMBL5275604)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50613103(CHEMBL5269847)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50613104(CHEMBL5268463)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50613105(CHEMBL5271811)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50613107(CHEMBL5267594)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501352(CHEMBL3922978)
Affinity DataIC50:  12nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50613106(CHEMBL5276709)
Affinity DataIC50:  13nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50613102(CHEMBL5285251)
Affinity DataIC50:  17nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50613101(CHEMBL5282927)
Affinity DataIC50:  17nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501354(CHEMBL3934222)
Affinity DataIC50:  18nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501357(CHEMBL3957297)
Affinity DataIC50:  48nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501351(CHEMBL3924425)
Affinity DataIC50:  110nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501353(CHEMBL3895001)
Affinity DataIC50:  230nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  310nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501356(CHEMBL2306366)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452869(CHEMBL4206009)
Affinity DataIC50:  6.35E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501356(CHEMBL2306366)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 decatenation incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha relaxationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501355(CHEMBL3952118)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed