Affinity DataIC50: 40nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human CYP2D6 after 20 to 50 mins by high-throughput fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human Nav1.5 expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily E member 1(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human cardiac slowly activating delayed rectifier K+ channel expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2D6 after 20 to 50 mins by high-throughput fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2D6 after 20 to 50 mins by high-throughput fluorescence assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily E member 1(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human cardiac slowly activating delayed rectifier K+ channel expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human Nav1.5 expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human Nav1.5 expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily E member 1(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human cardiac slowly activating delayed rectifier K+ channel expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: >4.10E+4nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair