Found 366 with Last Name = 'yao' and Initial = 'd' 
Affinity DataIC50: 1.70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Harbin Medical University
Curated by ChEMBL
Harbin Medical University
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Harbin Medical University
Curated by ChEMBL
Harbin Medical University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human His-tagged HDAC6 expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured af...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Shenzhen Technology University
Curated by ChEMBL
Shenzhen Technology University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC10 expressed in baculovirus infected Sf9 insect cells using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of PAK1 (unknown origin) using lipid substrate measured after 40 mins by ADP-glo kinase assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of PAK1 (unknown origin) using Syntide2 peptide as substrate by pyruvate kinase/LDH dehydrogenase coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Harbin Medical University
Curated by ChEMBL
Harbin Medical University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of His/thioredoxin-tagged human recombinant BRD4 bromodomain-1 (43 to 166 residues) expressed in Escherichia coli BL21 Star (DE3) pre-incu...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged BRD2 bromodomain-2 (339 to 459 residues) expressed in Escherichia coli expression system after ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of PAK2 (unknown origin) using lipid substrate measured after 40 mins by ADP-glo kinase assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 3(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of PAK3 (unknown origin) using lipid substrate measured after 40 mins by ADP-glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of native full length C-terminal USP7 (unknown origin) using ubiquitin-Rho110 as substrate pre-incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human His-tagged HDAC1 expressed in insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured after 30 mins by fluore...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMpH: 8.0Assay Description:The reaction mixture was consisted of 100 µL of the total volume. To the solution of PBS (pH 8.0, 30 µL) consisted of KH2PO4 and K2HPO4 in 96-well pl...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human His-tagged HDAC6 expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured af...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetNuclear receptor corepressor 1(Homo sapiens (Human))
Shenzhen Technology University
Curated by ChEMBL
Shenzhen Technology University
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant human GST-fused HDAC3/NCOR1 (397 to 503 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Ac)-A...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Harbin Medical University
Curated by ChEMBL
Harbin Medical University
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human His-tagged HDAC6 expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Shenzhen Technology University
Curated by ChEMBL
Shenzhen Technology University
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC10 expressed in baculovirus infected Sf9 insect cells using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged BRD3 bromodomain-1 (29 to 145 residues) expressed in Escherichia coli expression system after 1...More data for this Ligand-Target Pair
