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Found 58 with Last Name = 'jenkinson' and Initial = 'dh'
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50061977(17,25-diazonia-2,9-diazaheptacyclo[23.6.2.24,7.210...)
Affinity DataIC50:  3nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473100(CHEMBL344807)
Affinity DataIC50:  25nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473103(CHEMBL430146)
Affinity DataIC50:  28nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50435962(CHEMBL2391655)
Affinity DataIC50:  31nMAssay Description:Inhibition of KCa2.3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473097(CHEMBL136488)
Affinity DataIC50:  60nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50150389(17,23-diazonia-2,9-diazahexacyclo[21.6.2.24,7.210,...)
Affinity DataIC50:  60nMAssay Description:Inhibition of KCa2.3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473106(CHEMBL137175)
Affinity DataIC50:  70nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50084848(BIs-cyclo(4N-pentyl-1-(4-methylbenzyl)-4-quinolini...)
Affinity DataIC50:  80nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50084848(BIs-cyclo(4N-pentyl-1-(4-methylbenzyl)-4-quinolini...)
Affinity DataIC50:  80nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215069(1,2,3-tris-[3-(4-(N-ethyl)-quinoliniumylamino)-pro...)
Affinity DataIC50:  86nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473094(CHEMBL137155)
Affinity DataIC50:  90nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50289333(21,35-diazonia-2,13-diazaoctacyclo[33.6.2.214,21.1...)
Affinity DataIC50:  90nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215071(CHEMBL375272 | N-[3-(4-quinolinylamino)-propyl]-N-...)
Affinity DataIC50:  93nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473098(CHEMBL342213)
Affinity DataIC50:  100nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50084852(1,14-diazonia-22,33-diazaheptacyclo[32.6.2.214,21....)
Affinity DataIC50:  110nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50084852(1,14-diazonia-22,33-diazaheptacyclo[32.6.2.214,21....)
Affinity DataIC50:  110nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473099(CHEMBL140380)
Affinity DataIC50:  120nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215076(CHEMBL229982 | N-[3-(4-quinolinylamino)-propyl]-N-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473107(CHEMBL341700)
Affinity DataIC50:  130nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215070(1,2,3-tri[3-(4-quinolinylamino)-propoxy]-benzene |...)
Affinity DataIC50:  130nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473102(CHEMBL137266)
Affinity DataIC50:  150nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50084849(Bis-quinolinium cyclophane analogue | CHEMBL258254...)
Affinity DataIC50:  150nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50084849(Bis-quinolinium cyclophane analogue | CHEMBL258254...)
Affinity DataIC50:  150nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50084839(Bis-quinolinium cyclophane analogue | CHEMBL6266 |...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50084839(Bis-quinolinium cyclophane analogue | CHEMBL6266 |...)
Affinity DataIC50:  170nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50084851(Bis-quinolinium cyclophane analogue | CHEMBL266885...)
Affinity DataIC50:  180nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50084851(Bis-quinolinium cyclophane analogue | CHEMBL266885...)
Affinity DataIC50:  180nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50054105((Z)-1.1'-[stilbene-4,4'-diylbis(methylene)]bis(4-a...)
Affinity DataIC50:  190nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50054105((Z)-1.1'-[stilbene-4,4'-diylbis(methylene)]bis(4-a...)
Affinity DataIC50:  190nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473108(CHEMBL137116)
Affinity DataIC50:  210nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215075(CHEMBL229818 | N-[3-(4-quinolinylamino)-propyl]-3,...)
Affinity DataIC50:  220nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473111(CHEMBL137256)
Affinity DataIC50:  250nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473109(CHEMBL136303)
Affinity DataIC50:  260nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215072(CHEMBL389273 | N-(4-quinolinyl)-3,4-di-[3-(4-quino...)
Affinity DataIC50:  270nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473096(CHEMBL434234)
Affinity DataIC50:  280nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50054098(1,1'-[biphenyl-3,3'-diylbis(methylene)]-bis(4-amin...)
Affinity DataIC50:  290nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50054098(1,1'-[biphenyl-3,3'-diylbis(methylene)]-bis(4-amin...)
Affinity DataIC50:  290nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50084846(1-[7-(4-amino-1-quinoliniumylmethyl)-9H-2-fluoreny...)
Affinity DataIC50:  310nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50084846(1-[7-(4-amino-1-quinoliniumylmethyl)-9H-2-fluoreny...)
Affinity DataIC50:  310nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215068(CHEMBL229341 | N-[3-(4-quinolinylamino)-proyl]-3,5...)
Affinity DataIC50:  360nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473105(CHEMBL133311)
Affinity DataIC50:  360nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50054103(1,1'-[biphenyl-4,4'-diylbis(methylene)]-bis(4-amin...)
Affinity DataIC50:  380nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473101(CHEMBL344620)
Affinity DataIC50:  380nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50054103(1,1'-[biphenyl-4,4'-diylbis(methylene)]-bis(4-amin...)
Affinity DataIC50:  380nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50054095(1-{4-[4-(4-amino-1-quinoliniumylmethyl)phenethyl]b...)
Affinity DataIC50:  410nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50054095(1-{4-[4-(4-amino-1-quinoliniumylmethyl)phenethyl]b...)
Affinity DataIC50:  410nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50473110(CHEMBL337108)
Affinity DataIC50:  430nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50054096(1-{4-[4-(4-amino-1-quinoliniumylmethyl)benzyl]benz...)
Affinity DataIC50:  450nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50054096(1-{4-[4-(4-amino-1-quinoliniumylmethyl)benzyl]benz...)
Affinity DataIC50:  450nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50215073(CHEMBL229340 | N-[3-(4-quinolinyl)-aminopropyl]-N-...)
Affinity DataIC50:  490nMAssay Description:Inhibition of SKca channel-mediated after-hypepolarization in rat sympathetic neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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