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Found 197 with Last Name = 'jones' and Initial = 'dh'
TargetCalcium/calmodulin-dependent protein kinase type 1(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545573(CHEMBL4635883 | US11530193, Example 54)
Affinity DataIC50:  1nMAssay Description:Inhibition of human CAMK1A using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type 1G(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545573(CHEMBL4635883 | US11530193, Example 54)
Affinity DataIC50:  1nMAssay Description:Inhibition of human CAMK1G using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of PAK mediated recombinant LIMK1 phosphorylation (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545576(CHEMBL4640712 | US11530193, Example 50)
Affinity DataIC50:  2nMAssay Description:Inhibition of human CAMK1A using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of recombinant LIMK2(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1B(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545573(CHEMBL4635883 | US11530193, Example 54)
Affinity DataIC50:  3nMAssay Description:Inhibition of human CAMK1B using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1/2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50:  3nMAssay Description:Inhibition of LIMK1/LIMK2 in human SH-SY5Y cells assessed as effect on phospho cofilin serine 3 phosphorylation incubated for 2 hr by AlphaLISA SureF...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of recombinant LIMK1(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591314(CHEMBL5202859)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50043510(CHEMBL3355507)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of PAK mediated recombinant LIMK2 phosphorylation (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of recombinant LIMK2(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50249319(2-(2-aminoethylamino)-4-(3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human SYK using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of PAK mediated recombinant LIMK2 phosphorylation (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50043501(CHEMBL3355509)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50112355(CHEMBL3609326)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591314(CHEMBL5202859)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of PAK mediated recombinant LIMK2 phosphorylation (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545573(CHEMBL4635883 | US11530193, Example 54)
Affinity DataIC50:  8nMAssay Description:Inhibition of human CAMK1D using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545573(CHEMBL4635883 | US11530193, Example 54)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human full-length His-tagged CAMK1D expressed in baculovirus expression system using autocamtide-2 as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545576(CHEMBL4640712 | US11530193, Example 50)
Affinity DataIC50:  8nMAssay Description:Inhibition of HA-tagged CAMK1D (unknown origin) expressed in human MDA-MB-231 cells assessed as reduction in CAMK1D autophosphorylation measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50043501(CHEMBL3355509)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of PAK mediated recombinant LIMK2 phosphorylation (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545573(CHEMBL4635883 | US11530193, Example 54)
Affinity DataIC50:  11nMAssay Description:Inhibition of HA-tagged CAMK1D (unknown origin) expressed in human MDA-MB-231 cells assessed as reduction in CAMK1D autophosphorylation measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type 1B(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545576(CHEMBL4640712 | US11530193, Example 50)
Affinity DataIC50:  11nMAssay Description:Inhibition of human CAMK1B using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50112355(CHEMBL3609326)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50043510(CHEMBL3355507)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataIC50:  15nMAssay Description:Inhibition of PAK mediated recombinant LIMK2 phosphorylation (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591311(CHEMBL3182065)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant LIMK2(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591311(CHEMBL3182065)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545587(CHEMBL4633229 | US11530193, Example 135)
Affinity DataIC50:  19nMAssay Description:Inhibition of HA-tagged CAMK1D (unknown origin) expressed in human MDA-MB-231 cells assessed as reduction in CAMK1D autophosphorylation measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50:  21nMAssay Description:Inhibition of PAK mediated recombinant LIMK1 phosphorylation (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50:  21nMAssay Description:Inhibition of PAK mediated recombinant LIMK2 phosphorylation (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545587(CHEMBL4633229 | US11530193, Example 135)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human full-length His-tagged CAMK1D expressed in baculovirus expression system using autocamtide-2 as substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant LIMK1(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity mitogen-activated protein kinase kinase 5(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545573(CHEMBL4635883 | US11530193, Example 54)
Affinity DataIC50:  25nMAssay Description:Inhibition of human MEK5 using ERK5 as substrate in presence of [gamma-33P]-ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545576(CHEMBL4640712 | US11530193, Example 50)
Affinity DataIC50:  26nMAssay Description:Inhibition of human CAMK1D using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant LIMK1(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant LIMK2(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545586(CHEMBL4632457 | US11530193, Example 106)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant human full-length His-tagged CAMK1D expressed in baculovirus expression system using autocamtide-2 as substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant LIMK2(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545586(CHEMBL4632457 | US11530193, Example 106)
Affinity DataIC50:  28nMAssay Description:Inhibition of HA-tagged CAMK1D (unknown origin) expressed in human MDA-MB-231 cells assessed as reduction in CAMK1D autophosphorylation measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50591311(CHEMBL3182065)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50545576(CHEMBL4640712 | US11530193, Example 50)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant human full-length His-tagged CAMK1D expressed in baculovirus expression system using autocamtide-2 as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1/2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50112355(CHEMBL3609326)
Affinity DataIC50:  32nMAssay Description:Inhibition of LIMK1/LIMK2 in human SH-SY5Y cells assessed as effect on phospho cofilin serine 3 phosphorylation incubated for 2 hr by AlphaLISA SureF...More data for this Ligand-Target Pair
In DepthDetails PubMed
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