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Found 69 with Last Name = 'engelhardt' and Initial = 'e'
LigandPNGBDBM50223497(CHEMBL26232)
Affinity DataIC50:  16nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  18nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223493(CHEMBL24175)
Affinity DataIC50:  20nMAssay Description:Compound was tested for its ability to displace [3H]- naloxone] from Opioid receptors in absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111316(8-[4-(3,6-Dioxo-5-{4-[(thiophene-2-carbonyl)-amino...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  240nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in presence of NaCl (100 mM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223498(CHEMBL286206)
Affinity DataIC50:  287nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111273(6-Benzo[b]thiophen-2-yl-4-hydroxy-2-oxo-1,2-dihydr...)
Affinity DataIC50:  290nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111298(8-{4-[(7-Benzo[b]thiophen-2-yl-4-hydroxy-2-oxo-1,2...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111280(1-(4-Chloro-phenyl)-4-hydroxy-2-oxo-2,5-dihydro-1H...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223496(CHEMBL282347)
Affinity DataIC50:  301nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223493(CHEMBL24175)
Affinity DataIC50:  360nMAssay Description:Compound was tested for its ability to displace [3H]- naloxone] from Opioid receptors in presence of NaCl (100 mM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111292(8-{4-[(6-Benzo[b]thiophen-2-yl-4-hydroxy-2-oxo-1,2...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111316(8-[4-(3,6-Dioxo-5-{4-[(thiophene-2-carbonyl)-amino...)
Affinity DataIC50:  510nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111309(8-{4-[(6-Benzo[b]thiophen-3-yl-4-hydroxy-2-oxo-1,2...)
Affinity DataIC50:  510nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111281(8-{4-[(4-Hydroxy-7-naphthalen-2-yl-2-oxo-1,2-dihyd...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223497(CHEMBL26232)
Affinity DataIC50:  660nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in presence of NaCl (100 mM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111282(8-{4-[(4-Hydroxy-6-naphthalen-2-yl-2-oxo-1,2-dihyd...)
Affinity DataIC50:  670nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111280(1-(4-Chloro-phenyl)-4-hydroxy-2-oxo-2,5-dihydro-1H...)
Affinity DataIC50:  690nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111279(4-Hydroxy-2-oxo-1-p-tolyl-2,5-dihydro-1H-pyrrole-3...)
Affinity DataIC50:  830nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111279(4-Hydroxy-2-oxo-1-p-tolyl-2,5-dihydro-1H-pyrrole-3...)
Affinity DataIC50:  890nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111286(8-{4-[(7-Cyano-4-hydroxy-2-oxo-1,2-dihydro-quinoli...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111309(8-{4-[(6-Benzo[b]thiophen-3-yl-4-hydroxy-2-oxo-1,2...)
Affinity DataIC50:  940nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111273(6-Benzo[b]thiophen-2-yl-4-hydroxy-2-oxo-1,2-dihydr...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by complex assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111284(8-{4-[(4-Hydroxy-2-oxo-7-trifluoromethyl-1,2-dihyd...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223494(CHEMBL1159833)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223495(CHEMBL25778)
Affinity DataIC50:  1.54E+3nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111299(8-{4-[(4-Hydroxy-6,7-dimethoxy-2-oxo-1,2-dihydro-q...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111319(8-{4-[(4-Hydroxy-2-oxo-6-pentyl-1,2-dihydro-quinol...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111306(8-{4-[(4-Hydroxy-2-oxo-1,2-dihydro-quinoline-3-car...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111285(8-(4-(4-hydroxy-2-oxo-1-p-tolyl-2,5-dihydro-1H-pyr...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111313(8-{4-[(6-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinol...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111288(8-(4-{[1-(4-Bromo-phenyl)-4-hydroxy-2-oxo-2,5-dihy...)
Affinity DataIC50:  1.99E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111295(8-(4-{[6-(4-Chloro-phenyl)-4-hydroxy-2-oxo-1,2-dih...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111308(8-{4-[(4-Hydroxy-6-iodo-2-oxo-1,2-dihydro-quinolin...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111314(8-{4-[(6,7-Difluoro-4-hydroxy-2-oxo-1,2-dihydro-qu...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111296(8-(4-{[4-Hydroxy-1-(4-isopropyl-phenyl)-2-oxo-2,5-...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111303(8-{4-[(5-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinol...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223495(CHEMBL25778)
Affinity DataIC50:  3.35E+3nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in presence of NaCl (100 mM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111277(8-{4-[(4-Hydroxy-6-nitro-2-oxo-1,2-dihydro-quinoli...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111283(8-(4-{[4-Hydroxy-1-(4-methoxy-phenyl)-2-oxo-2,5-di...)
Affinity DataIC50:  3.66E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111304(8-{4-[(4-Hydroxy-1-naphthalen-2-yl-2-oxo-2,5-dihyd...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111300(8-{4-[(5-Amino-4-hydroxy-2-oxo-1,2-dihydro-quinoli...)
Affinity DataIC50:  4.25E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111312(8-(4-{[4-Hydroxy-1-(4-nitro-phenyl)-2-oxo-2,5-dihy...)
Affinity DataIC50:  4.25E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111289(8-{4-[(6-Fluoro-4-hydroxy-2-oxo-1,2-dihydro-quinol...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111274(8-(4-(1-(4-chlorophenyl)-4-hydroxy-2-oxo-2,5-dihyd...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223496(CHEMBL282347)
Affinity DataIC50:  5.59E+3nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in presence of NaCl (100 mM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223494(CHEMBL1159833)
Affinity DataIC50:  6.38E+3nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in presence of NaCl (100 mM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111318(8-{4-[(4-Hydroxy-5-iodo-2-oxo-1,2-dihydro-quinolin...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50111305(8-{4-[(4-Hydroxy-5-nitro-2-oxo-1,2-dihydro-quinoli...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223498(CHEMBL286206)
Affinity DataIC50:  8.18E+3nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in presence of NaCl (100 mM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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