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Found 41 with Last Name = 'jagu' and Initial = 'e'
TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50096500(CHEMBL86281 | N,N'-Bis-(3-phenyl-propyl)-N,N'-bis-...)
Affinity DataKi:  600nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Crithidia fasciculata)TBA
LigandPNGBDBM50240622(3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[3-(3,4-dihydr...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Crithidia fasciculata TryR overexpressed in escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615394(CHEMBL5266592)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50096496(CHEMBL62048 | N,N'-Bis-(3-amino-propyl)-N,N'-bis-(...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50096493(CHEMBL82641 | N,N'-Bis-(3-phenyl-propyl)-N-[3-(3-p...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50408797(CHEMBL151228)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50462235(CHEMBL4244566)
Affinity DataKi:  7.50E+3nMAssay Description:Mixed-type inhibition of Trypanosoma brucei trypanothione reductase assessed as enzyme-inhibitor complex using varying levels of TS2 as substrate in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50096498(CHEMBL86096 | N,N'-Bis-[3-(3-phenyl-propylamino)-p...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615395(CHEMBL5280891)
Affinity DataKi:  1.59E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50009371(1, 12-DB-3-4-3 | CHEMBL81614 | N,N'-Bis-(3-benzyla...)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50462235(CHEMBL4244566)
Affinity DataKi:  2.00E+4nMAssay Description:Mixed-type inhibition of Trypanosoma brucei trypanothione reductase assessed as enzyme-inhibitor-substrate complex using varying levels of TS2 as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615396(CHEMBL311566)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50096497(CHEMBL85779 | N-(3-Amino-propyl)-N'-[3-(3-phenyl-p...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Crithidia fasciculata)TBA
LigandPNGBDBM50615384(CHEMBL80264)
Affinity DataKi:  8.50E+4nMAssay Description:Inhibition of Crithidia fasciculata TryR overexpressed in escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615399(CHEMBL82315)
Affinity DataKi:  8.60E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant by TR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615398(CHEMBL77450)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant by TR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615397(CHEMBL210576)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50184788((4-Amino-butyl)-(3-amino-propyl)-carbamic acid ben...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50615382(CHEMBL211029)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50184783(CHEMBL298628 | N*1*-(3-Amino-propyl)-N*1*-naphthal...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615393(CHEMBL2008816)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615391(CHEMBL5277812)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615390(CHEMBL210734)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615392(CHEMBL2009956)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione synthetase(Crithidia fasciculata)TBA
LigandPNGBDBM50615400(CHEMBL4092938)
Affinity DataIC50:  30nMAssay Description:Inhibition of Crithidia fasciculata His tagged TryS in presence of ATP by LDH/PK assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615386(CHEMBL5283195)
Affinity DataIC50:  200nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50070270(CHEMBL279374 | Pentanedioic acid bis-[(3-{4-bromo-...)
Affinity DataIC50:  550nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615388(CHEMBL5280255)
Affinity DataIC50:  600nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50615401(CHEMBL5081809)
Affinity DataIC50:  750nMAssay Description:Inhibition of Trypanosoma brucei TryRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615389(CHEMBL5283514)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615385(CHEMBL5270809)
Affinity DataIC50:  930nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615383(CHEMBL5273760)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR expressed in escherichia coli SG5More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM77970(3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR measured after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615387(CHEMBL5286658)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM78434(2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]p...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of Trypanosoma brucei TryRMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50462235(CHEMBL4244566)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of Trypanosoma brucei trypanothione reductase using TS2 as substrate in presence of NADPH by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50285025(CHEMBL305575 | N-Naphthalen-2-ylmethyl-N'-{3-[(nap...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
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TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM50087158(5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human glutathione reductaseMore data for this Ligand-Target Pair
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TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM50087155(5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human glutathione reductaseMore data for this Ligand-Target Pair
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TargetTrypanothione reductase(Trypanosoma cruzi)TBA
LigandPNGBDBM50615381(CHEMBL5269894)
Affinity DataIC50: >5.70E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR expressed in escherichia coli in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed