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Found 77 with Last Name = 'nilsson' and Initial = 'e'
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21625(2-phenyl-5-(1H-pyrazol-3-yl)-1,3-thiazole | 2-phen...)
Affinity DataIC50:  21nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350728(CHEMBL1818291)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21627(N-[4-methyl-3-({3-[(4-methylpiperazin-1-yl)methyl]...)
Affinity DataIC50:  75nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350748(CHEMBL1818297)
Affinity DataIC50:  89nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350750(CHEMBL1818300)
Affinity DataIC50:  99nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350747(CHEMBL1818296)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350753(CHEMBL1818303)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21624(4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]a...)
Affinity DataIC50:  138nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350750(CHEMBL1818300)
Affinity DataIC50:  150nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  170nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350747(CHEMBL1818296)
Affinity DataIC50:  190nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350732(CHEMBL1818187)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350739(CHEMBL1818194)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350746(CHEMBL1818295)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  230nMAssay Description:Inhibition of obese Zucker rat ACC1 assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malachit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350728(CHEMBL1818291)
Affinity DataIC50:  240nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350744(CHEMBL1818293)
Affinity DataIC50:  240nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350750(CHEMBL1818300)
Affinity DataIC50:  250nMAssay Description:Inhibition of obese Zucker rat ACC1 assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malachit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350742(CHEMBL1615283)
Affinity DataIC50:  330nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350747(CHEMBL1818296)
Affinity DataIC50:  460nMAssay Description:Inhibition of obese Zucker rat ACC1 assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malachit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350740(CHEMBL1818195)
Affinity DataIC50:  570nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350755(CHEMBL1818299)
Affinity DataIC50:  630nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350752(CHEMBL1818302)
Affinity DataIC50:  680nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350749(CHEMBL1818298)
Affinity DataIC50:  690nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350731(CHEMBL1818186)
Affinity DataIC50:  690nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350745(CHEMBL1818294)
Affinity DataIC50:  730nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350743(CHEMBL1818292)
Affinity DataIC50:  750nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350748(CHEMBL1818297)
Affinity DataIC50:  780nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350736(CHEMBL1818191)
Affinity DataIC50:  780nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350728(CHEMBL1818291)
Affinity DataIC50:  800nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21626(3-phenyl-5-(1H-pyrazol-3-yl)-1,2-oxazole | 3-pheny...)
Affinity DataIC50:  920nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21616(4-{[4-(2-methoxyphenyl)-1,3-thiazol-2-yl]amino}ben...)
Affinity DataIC50:  994nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350753(CHEMBL1818303)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350733(CHEMBL1818188)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350750(CHEMBL1818300)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350739(CHEMBL1818194)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350747(CHEMBL1818296)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350744(CHEMBL1818293)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350741(CHEMBL1818290)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350751(CHEMBL1818301)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21628(Pyridine-3-carboxylate | methyl 6-(3-pyridin-4-yl-...)
Affinity DataIC50:  1.50E+3nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350754(CHEMBL1817676)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350742(CHEMBL1615283)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350746(CHEMBL1818295)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350740(CHEMBL1818195)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350728(CHEMBL1818291)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350729(CHEMBL1818184)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350743(CHEMBL1818292)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350738(CHEMBL1818193)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development

Curated by ChEMBL
LigandPNGBDBM50350730(CHEMBL1818185)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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