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TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM129823(US8815926, 102)
Affinity DataKi:  0.210nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50433561(CHEMBL2381408)
Affinity DataKi:  0.880nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50448936(CHEMBL3125527 | US9296736, 342 | US9593129, Exampl...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of p53-MDM2 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50448969(CHEMBL3125517 | US9296736, 256 | US9593129, Exampl...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of p53-MDM2 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571706(CHEMBL4850588)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571710(CHEMBL4872224)
Affinity DataIC50:  4nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571708(CHEMBL4873348)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571711(CHEMBL4860092)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50467678(Ds-3032 | Milademetan)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571714(CHEMBL4874518)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571709(CHEMBL4853818)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571705(CHEMBL4865567)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571707(CHEMBL4850002)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542943(CHEMBL4646293)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human C-terminal Ig-Fc-tagged PD1 (Leu25 to Gln167 residues) expressed in HEK293 cells/human C-terminal epitope-His-tagged PDL1 (Phe19 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542943(CHEMBL4646293)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542963(CHEMBL4638650)
Affinity DataIC50:  8nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542964(CHEMBL4646486)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542966(CHEMBL4635932)
Affinity DataIC50:  9nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542978(CHEMBL4648161)
Affinity DataIC50:  10nMAssay Description:Inhibition of human C-terminal Ig-Fc-tagged PD1 (Leu25 to Gln167 residues) expressed in HEK293 cells/human C-terminal epitope-His-tagged PDL1 (Phe19 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542976(CHEMBL4636606 | US11535615, Example 1)
Affinity DataIC50: <10nMAssay Description:Inhibition of human Fc-tagged PD1 N-terminal domain (Leu25 to Gln167 residues) expressed in HEK293 cells/human His-tagged PDL1 (Phe19 to Arg238 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50239948(CHEMBL4071326 | US9850225, Example 1166)
Affinity DataIC50:  10nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542949(CHEMBL4646667)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571718(CHEMBL4849851)
Affinity DataIC50:  12nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542954(CHEMBL4639202)
Affinity DataIC50:  13nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542954(CHEMBL4639202)
Affinity DataIC50:  13nMAssay Description:Inhibition of human C-terminal Ig-Fc-tagged PD1 (Leu25 to Gln167 residues) expressed in HEK293 cells/human C-terminal epitope-His-tagged PDL1 (Phe19 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542952(CHEMBL4646568)
Affinity DataIC50:  13nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542965(CHEMBL4645569)
Affinity DataIC50:  14nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)
Affinity DataIC50:  15nMAssay Description:Inhibition G9a (unknown origin)More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542944(CHEMBL4648149)
Affinity DataIC50:  15nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542947(CHEMBL4640374)
Affinity DataIC50:  15nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542945(CHEMBL4641441)
Affinity DataIC50:  15nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542951(CHEMBL4639656)
Affinity DataIC50:  17nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571727(CHEMBL4869055)
Affinity DataIC50:  18nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50:  18nMAssay Description:Inhibition of JAK2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50:  18nMAssay Description:Inhibition of TRKA (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50:  20nMAssay Description:Inhibition of JAK3 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50087289(1-beta-D-Arabinofuranosylcytosine | 4-Amino-1-beta...)
Affinity DataIC50:  20nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571726(CHEMBL4877387)
Affinity DataIC50:  21nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50:  22nMAssay Description:Inhibition of TYK2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571722(CHEMBL4858762)
Affinity DataIC50:  23nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50:  24nMAssay Description:Inhibition of Pyk2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571719(CHEMBL4863844)
Affinity DataIC50:  24nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542930(CHEMBL4648618)
Affinity DataIC50:  25nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542934(CHEMBL4637912)
Affinity DataIC50:  26nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  27nMAssay Description:Inhibition of TRKA (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50542946(CHEMBL4644097)
Affinity DataIC50:  28nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  28nMAssay Description:Inhibition of JAK2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571715(CHEMBL4849923)
Affinity DataIC50:  29nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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