Affinity DataIC50: 8nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 11nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated for 17 hrs ...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated for 16 to 1...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP assessed as reduction in amyloid beta42 level incubated for 22 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 210nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP assessed as reduction in amyloid beta42 level incubated for 22 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 470nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair