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Found 102 with Last Name = 'quintini' and Initial = 'g'
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331277(3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331277(3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...)
Affinity DataIC50:  60nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331273(3-(6-methyl-1H-indol-2-yl)-1H-indazole-6-carbonitr...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331280(3-(6-methyl-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyrid...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331274(6-fluoro-3-(6-methoxy-1H-indol-2-yl)-1H-indazole |...)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331268(3-(1H-indol-2-yl)-1H-indazole-5-carbonitrile | CHE...)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331269(3-(1H-indol-2-yl)-1H-indazole-6-carbonitrile | CHE...)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331271(6-methyl-3-(6-methyl-1H-indol-2-yl)-1H-indazole | ...)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331262(3-(6-methyl-1H-indol-2-yl)-1H-indazole | CHEMBL128...)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331258(3-(5-methoxy-1H-indol-2-yl)-1H-indazole | CHEMBL12...)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331259(3-(6-methoxy-1H-indol-2-yl)-1H-indazole | CHEMBL12...)
Affinity DataIC50:  130nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331272(6-fluoro-3-(6-methyl-1H-indol-2-yl)-1H-indazole | ...)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331257(3-(1H-indol-2-yl)-1H-indazole | CHEMBL1288974)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  160nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331265(3-(1H-indol-2-yl)-6-methyl-1H-indazole | CHEMBL128...)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331266(5-fluoro-3-(1H-indol-2-yl)-1H-indazole | CHEMBL128...)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331267(6-fluoro-3-(1H-indol-2-yl)-1H-indazole | CHEMBL128...)
Affinity DataIC50:  190nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331277(3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...)
Affinity DataIC50:  190nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331275(3-(1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyridine | CHE...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331282(3-(6-bromo-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyridi...)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331281(3-(4-bromo-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyridi...)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331264(3-(1H-indol-2-yl)-5-methyl-1H-indazole | CHEMBL128...)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331277(3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...)
Affinity DataIC50:  270nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331276(3-(5-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331279(3-(5-methyl-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyrid...)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331277(3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...)
Affinity DataIC50:  310nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331270(5-methyl-3-(6-methyl-1H-indol-2-yl)-1H-indazole | ...)
Affinity DataIC50:  310nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320969(CHEMBL1164353 | Phenyl-1H-pyrazol-3-yl)-1H-indole-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331261(3-(5-methyl-1H-indol-2-yl)-1H-indazole | CHEMBL128...)
Affinity DataIC50:  350nMAssay Description:Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320970(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  400nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320992(2-(5-Benzyl-1H-pyrazol-3-yl)-3-[(4-fluorobenzylami...)
Affinity DataIC50:  500nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  540nMAssay Description:Inhibition of GST-tagged full length GSK3-beta assessed as inhibition of ATP consumption after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320979(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  560nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320978(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320970(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  630nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320994(2-(5-Benzyl-1H-pyrazol-3-yl)-3-morpholin-4-ylmethy...)
Affinity DataIC50:  630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  790nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320991(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  850nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320989(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320972(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of GST-tagged full length GSK3-beta assessed as inhibition of ATP consumption after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320977(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331277(3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50331277(3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of CDK4/Cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320987(2-(5-Benzyl-1H-pyrazol-3-yl)-3-hydroxymethyl-1Hind...)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320975(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320974(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50320971(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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