TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards human Prostanoid IP receptor in CHO cells.More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards human Prostanoid IP receptor in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards human Prostanoid IP receptor in CHO cells.More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataKi: >0.000100nMAssay Description:Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.00205nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0216nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0350nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0618nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0623nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University of Occupational and Environmental Health
Curated by PDSP Ki Database
University of Occupational and Environmental Health
Curated by PDSP Ki Database
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.172nMAssay Description:Ability of the compound to displace [3H]-DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical
Curated by ChEMBL
Dainippon Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University of Occupational and Environmental Health
Curated by PDSP Ki Database
University of Occupational and Environmental Health
Curated by PDSP Ki Database
Affinity DataKi: 0.430nMAssay Description:Displacement of [125I]T3 from human recombinant thyroid harmone receptor beta after 16 to 48 hrs by gamma-ray detectionMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataKi: 0.740nMAssay Description:Compound was evaluated for its competitive binding affinity towards human Prostanoid EP2 receptor in CHO cells expressing prostanoid receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical
Curated by ChEMBL
Dainippon Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical
Curated by ChEMBL
Dainippon Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.970nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]iodocyanopindolol binding to Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Ability of the compound to displace [3H]-deltorphin II from delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.13nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
Affinity DataKi: 1.19nMAssay Description:Displacement of [125I]T3 from human recombinant thyroid harmone receptor beta after 16 to 48 hrs by gamma-ray detectionMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of 5-hydroxytryptamine 2 induced vasoconstriction of rat caudal artery.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University of Occupational and Environmental Health
Curated by PDSP Ki Database
University of Occupational and Environmental Health
Curated by PDSP Ki Database
Affinity DataKi: 1.54nMAssay Description:Displacement of [125I]T3 from human recombinant thyroid harmone receptor beta after 16 to 48 hrs by gamma-ray detectionMore data for this Ligand-Target Pair
Affinity DataKi: 1.73nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.81nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).More data for this Ligand-Target Pair
Affinity DataKi: 2.02nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).More data for this Ligand-Target Pair
Affinity DataKi: 2.03nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
Affinity DataKi: 2.04nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [125I]-T3 from human TRbeta expressed in insect cells after 16 to 48 hrs by gamma-countingMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity towards mouse Prostanoid EP2 receptor expressed in CHO cells.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nippon Organon K.K.
Curated by ChEMBL
Nippon Organon K.K.
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE) from human acute monocytic leukemia cell line.More data for this Ligand-Target Pair
Affinity DataKi: 2.29nMAssay Description:Displacement of [125I]T3 from human recombinant thyroid harmone receptor beta after 16 to 48 hrs by gamma-ray detectionMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [125I]-T3 from human TRalpha expressed in insect cells after 16 to 48 hrs by gamma-countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [125I]-T3 from human TRbeta expressed in insect cells after 16 to 48 hrs by gamma-countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.33nMAssay Description:Displacement of [125I]T3 from human recombinant thyroid harmone receptor alpha after 16 to 48 hrs by gamma-ray detectionMore data for this Ligand-Target Pair
Affinity DataKi: 2.43nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair
Affinity DataKi: 2.45nMAssay Description:Displacement of [125I]T3 from human recombinant thyroid harmone receptor alpha after 16 to 48 hrs by gamma-ray detectionMore data for this Ligand-Target Pair