Compile Data Set for Download or QSAR
maximum 50k data
Found 52 with Last Name = 'numata' and Initial = 'h'
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037039(2-Amino-5,7-dimethyl-4-pyridin-3-ylmethyl-benzothi...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173167((S)-(2-(4-fluorophenyl)-3-(2-(propylamino)pyrimidi...)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173169(CHEMBL383799 | [(R)-2-(4-Fluoro-phenyl)-3-(2-propy...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50:  9nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50037040(2-Ethylamino-5,7-dimethyl-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173173(CHEMBL383348 | {4-[(S)-2-(4-Fluoro-phenyl)-5-(4-me...)
Affinity DataIC50:  10.9nMAssay Description:Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173167((S)-(2-(4-fluorophenyl)-3-(2-(propylamino)pyrimidi...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against p38 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50037044(4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylami...)
Affinity DataIC50:  30nMAssay Description:Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173169(CHEMBL383799 | [(R)-2-(4-Fluoro-phenyl)-3-(2-propy...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against p38 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173166(CHEMBL371720 | N-{3-[4-(3-Azido-phenyl)-5-pyridin-...)
Affinity DataIC50:  46nMAssay Description:Inhibitory concentration against p38 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173173(CHEMBL383348 | {4-[(S)-2-(4-Fluoro-phenyl)-5-(4-me...)
Affinity DataIC50:  54nMAssay Description:Inhibitory activity against p38 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173168(4-[(S)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...)
Affinity DataIC50:  61.2nMAssay Description:Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037036(5,7-Dimethoxy-2-[(pyridin-3-ylmethyl)-amino]-benzo...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037051(5,7-Dimethyl-2-propylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037040(2-Ethylamino-5,7-dimethyl-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037046(2-Amino-5-methoxy-7-methyl-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173172(4-[(R)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...)
Affinity DataIC50:  116nMAssay Description:Inhibitory activity against p38 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173171(CHEMBL199247 | N-(3-(4-(4-fluorophenyl)-5-(pyridin...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037041(2-Amino-7-ethyl-5-methoxy-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037045(5-Methoxy-7-methyl-2-methylamino-4-pyridin-3-ylmet...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037046(2-Amino-5-methoxy-7-methyl-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037041(2-Amino-7-ethyl-5-methoxy-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037039(2-Amino-5,7-dimethyl-4-pyridin-3-ylmethyl-benzothi...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50:  210nMAssay Description:Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037044(4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylami...)
Affinity DataIC50:  210nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173170(CHEMBL198261 | {4-[(R)-2-(4-Fluoro-phenyl)-5-(4-me...)
Affinity DataIC50:  217nMAssay Description:Inhibitory activity against p38 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50:  230nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037038(2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173170(CHEMBL198261 | {4-[(R)-2-(4-Fluoro-phenyl)-5-(4-me...)
Affinity DataIC50:  233nMAssay Description:Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037047(2-Amino-4,5-dimethyl-7-pyridin-3-ylmethyl-benzothi...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173172(4-[(R)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...)
Affinity DataIC50:  270nMAssay Description:Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037043(2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  270nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50173168(4-[(S)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...)
Affinity DataIC50:  295nMAssay Description:Inhibitory activity against p38 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037053(4,7-Dimethyl-2-methylamino-5-pyridin-3-ylmethyl-be...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037048(7-Ethyl-5-methoxy-2-methylamino-4-pyridin-3-ylmeth...)
Affinity DataIC50:  330nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50037038(2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  390nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  420nMAssay Description:In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037038(2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  650nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50037043(2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  810nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037040(2-Ethylamino-5,7-dimethyl-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  910nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037045(5-Methoxy-7-methyl-2-methylamino-4-pyridin-3-ylmet...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037050(4-Phenyl-2-[(pyridin-3-ylmethyl)-amino]-benzothiaz...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037042(4-Methyl-2-[(pyridin-3-ylmethyl)-amino]-naphtho[1,...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037049(4,5,7-Trimethyl-2-[(pyridin-3-ylmethyl)-amino]-ben...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037043(2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037042(4-Methyl-2-[(pyridin-3-ylmethyl)-amino]-naphtho[1,...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037052(4,7-Dimethyl-2-[(pyridin-3-ylmethyl)-amino]-benzot...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037047(2-Amino-4,5-dimethyl-7-pyridin-3-ylmethyl-benzothi...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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