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Found 32 with Last Name = 'ewida' and Initial = 'ha'
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226165(N'-[4-Methoxybenzylidene-2-(6-chloro)-3-(4-met...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 1(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human HDAC1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50316147(CHEMBL4171675)
Affinity DataIC50:  20nMAssay Description:Inhibition of human HDAC2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human HDAC2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  31nMAssay Description:Inhibition of HDAC3 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50316146(CHEMBL4163794)
Affinity DataIC50:  32nMAssay Description:Inhibition of human HDAC2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50316147(CHEMBL4171675)
Affinity DataIC50:  32nMAssay Description:Inhibition of HDAC3 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50316146(CHEMBL4163794)
Affinity DataIC50:  38nMAssay Description:Inhibition of human HDAC1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50316146(CHEMBL4163794)
Affinity DataIC50:  64nMAssay Description:Inhibition of HDAC3 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50316147(CHEMBL4171675)
Affinity DataIC50:  70nMAssay Description:Inhibition of human HDAC1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  80nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  125nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50316147(CHEMBL4171675)
Affinity DataIC50:  202nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Ahram Canadian University

Curated by ChEMBL
LigandPNGBDBM50316146(CHEMBL4163794)
Affinity DataIC50:  295nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226173(6-Chloro-2-((5-(4-chlorophenylamino)-1,3,4-thiadia...)
Affinity DataIC50:  400nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226170(1-[2-(6,7-Dimethoxy)-3-(4-methoxy-phenyl)-4-oxo-3,...)
Affinity DataIC50:  600nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226163(2-[(6,7-Dimethoxy)-3-(4-methoxyphenyl)-4-oxo-3,4-d...)
Affinity DataIC50:  800nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226168(1-[2-(6-Chloro)-3-(4-methoxy-phenyl)-4-oxo-3,4-dih...)
Affinity DataIC50:  1.20E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226160(Ethyl 2-(6-chloro-3-(4-methoxyphenyl)-4-oxo-3,4-di...)
Affinity DataIC50:  1.70E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226174(6-chloro-2-((5-(4-methoxyphenylamino)-1,3,4-thiadi...)
Affinity DataIC50:  4.40E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226162(2-[6-Chloro-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroq...)
Affinity DataIC50:  7.50E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226166(N'-[4-Chlorobenzylidene-2-(6,7-dimethoxy)-3-(4...)
Affinity DataIC50:  7.60E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226167(N'-[4-Methoxybenzylidene-2-(6,7-dimethoxy)-3-(...)
Affinity DataIC50:  8.00E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226172((6,7-Dimethoxy)-2-((4-(4-methoxyphenyl)-5-mercapto...)
Affinity DataIC50:  1.08E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226171((6,7-Dimethoxy)-2-((4-(4-chlorophenyl)-5-mercapto-...)
Affinity DataIC50:  1.10E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226158(6-Chloro-2-mercapto-3-(4-methoxyphenyl)quinazolin-...)
Affinity DataIC50:  1.15E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226176(6,7-Dimethoxy-2-((5-(4-methoxyphenylamino)-1,3,4-t...)
Affinity DataIC50:  1.18E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226161(Ethyl 2-(6,7-dimethoxy-3-(4-methoxyphenyl)-4-oxo-3...)
Affinity DataIC50:  1.44E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226175(6,7-Dimethoxy-2-((5-(4-chlorophenylamino)-1,3,4-th...)
Affinity DataIC50:  1.47E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226164(N'-[4-Chlorobenzylidene-2-(6-chloro)-3-(4-meth...)
Affinity DataIC50:  1.90E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226159((6,7-Dimethoxy)-2-mercapto-3-(4-methoxyphenyl)quin...)
Affinity DataIC50:  2.90E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

LigandPNGBDBM226169(1-[2-(6,7-Dimethoxy)-3-(4-methoxy-phenyl)-4-oxo-3,...)
Affinity DataIC50:  5.60E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails