Compile Data Set for Download or QSAR
maximum 50k data
Found 26 with Last Name = 'greguric' and Initial = 'i'
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243005(2-(6-Chloro-2-(4-(2-fluoroethoxy)phenyl)imidazo[1,...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243006(2-(6-Chloro-2-(4-(3-fluoropropoxy)phenyl)imidazo[1...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243008(CHEMBL469682 | N,N-Diethyl-2-(2-(4-(3-fluoropropox...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243006(2-(6-Chloro-2-(4-(3-fluoropropoxy)phenyl)imidazo[1...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243007(2-(2-(4-(2-Fluoroethoxy)phenyl)-5,7-dimethylpyrazo...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243007(2-(2-(4-(2-Fluoroethoxy)phenyl)-5,7-dimethylpyrazo...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243008(CHEMBL469682 | N,N-Diethyl-2-(2-(4-(3-fluoropropox...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243005(2-(6-Chloro-2-(4-(2-fluoroethoxy)phenyl)imidazo[1,...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217008(CHEMBL230904 | N-(1-(2-fluoroethyl)piperidin-4-yl)...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217012(CHEMBL231120 | N-(4-(2-azanorborn-2-yl)butyl)-4-io...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217015(CHEMBL231119 | N-(1-(2-hydroxyethyl)piperidin-4-yl...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217014(CHEMBL230903 | N-(2-(diethylamino)ethyl)-5-iodo-2-...)
Affinity DataKi:  650nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217009(4-acetamido-N-(4-(2-azanorborn-2-yl)butyl)-5-iodo-...)
Affinity DataKi:  680nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217013(CHEMBL230692 | N-(2-(diethylamino)ethyl)-5-iodo-2-...)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217018(CHEMBL395005 | N-(4-(dipropylamino)butyl)-4-iodobe...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217010(4-acetamido-N-(4-(N-butyl-N-methylamino)butyl)-5-i...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50092740(4-Acetylamino-N-(2-diethylamino-ethyl)-5-iodo-2-me...)
Affinity DataKi:  1.65E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217011(4-acetamido-N-(4-(butylamino)butyl)-5-iodo-2-metho...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217016(4-acetamido-N-(4-(N-isopropyl-N-methylamino)butyl)...)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217017(4-acetamido-N-(4-(dipropylamino)butyl)-5-iodo-2-me...)
Affinity DataKi:  7.80E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Mus musculus (Mouse))
The Australian Nuclear Science and Technology Organisation

Curated by ChEMBL
LigandPNGBDBM50060964((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [3H]prazosin from alpha1 adrenoceptor in C57BL/6 mouse hippocampal homogenates after 40 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Mus musculus (Mouse))
The Australian Nuclear Science and Technology Organisation

Curated by ChEMBL
LigandPNGBDBM39687((2E)-1-ethyl-2-[(1-ethyl-2-quinolin-1-iumyl)methyl...)
Affinity DataIC50:  60nMAssay Description:Displacement of [3H]prazosin from alpha1 adrenoceptor in C57BL/6 mouse hippocampal homogenates after 40 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Mus musculus (Mouse))
The Australian Nuclear Science and Technology Organisation

Curated by ChEMBL
LigandPNGBDBM50270777(CHEMBL4126353)
Affinity DataIC50:  348nMAssay Description:Displacement of [3H]prazosin from alpha1 adrenoceptor in C57BL/6 mouse hippocampal homogenates after 40 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Mus musculus (Mouse))
The Australian Nuclear Science and Technology Organisation

Curated by ChEMBL
LigandPNGBDBM50270778(CHEMBL4126498)
Affinity DataIC50:  577nMAssay Description:Displacement of [3H]prazosin from alpha1 adrenoceptor in C57BL/6 mouse hippocampal homogenates after 40 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Mus musculus (Mouse))
The Australian Nuclear Science and Technology Organisation

Curated by ChEMBL
LigandPNGBDBM50270779(CHEMBL4129778)
Affinity DataIC50:  711nMAssay Description:Displacement of [3H]prazosin from alpha1 adrenoceptor in C57BL/6 mouse hippocampal homogenates after 40 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Mus musculus (Mouse))
The Australian Nuclear Science and Technology Organisation

Curated by ChEMBL
LigandPNGBDBM50270772(CHEMBL4128701)
Affinity DataIC50:  1.07E+3nMAssay Description:Displacement of [3H]prazosin from alpha1 adrenoceptor in C57BL/6 mouse hippocampal homogenates after 40 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed