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Found 128 with Last Name = 'gomez-monterrey' and Initial = 'im'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591532(CHEMBL4590950)
Affinity DataIC50:  61nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591533(CHEMBL4449485)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591535(CHEMBL5185907)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591533(CHEMBL4449485)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591532(CHEMBL4590950)
Affinity DataIC50:  280nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591524(CHEMBL5202375)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591539(CHEMBL5170803)
Affinity DataIC50:  410nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591539(CHEMBL5170803)
Affinity DataIC50:  430nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591522(CHEMBL4473010)
Affinity DataIC50:  450nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591534(CHEMBL5199450)
Affinity DataIC50:  570nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591539(CHEMBL5170803)
Affinity DataIC50:  590nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591531(CHEMBL5193145)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591526(CHEMBL5169630)
Affinity DataIC50:  910nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591534(CHEMBL5199450)
Affinity DataIC50:  950nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591526(CHEMBL5169630)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591524(CHEMBL5202375)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591522(CHEMBL4473010)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591522(CHEMBL4473010)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591529(CHEMBL4458075)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591525(CHEMBL5185080)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591535(CHEMBL5185907)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591540(CHEMBL5204046)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591536(CHEMBL5191521)
Affinity DataIC50:  2.29E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591528(CHEMBL5207672)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591531(CHEMBL5193145)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591528(CHEMBL5207672)
Affinity DataIC50:  2.93E+3nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591534(CHEMBL5199450)
Affinity DataIC50:  3.86E+3nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591524(CHEMBL5202375)
Affinity DataIC50:  4.87E+3nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591531(CHEMBL5193145)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50510133(CHEMBL4446681)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused FGFR3 C-terminal domain (R397 to T806 residues) expressed in Sf9 insect cells usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50510133(CHEMBL4446681)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-His6-fused TRKB C-terminal domain (V526 to G838 residues) expressed in Sf9 insect cells using Poly(Glu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSRSF protein kinase 1(Homo sapiens (Human))
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50510133(CHEMBL4446681)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-His6-fused SRPK1 (M1 to S655 residues) expressed in Sf9 insect cells using RS-peptide as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50510133(CHEMBL4446681)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-His6-fused ERBB4 C-terminal domain (R676 to V1307 residues) expressed in Sf9 cells using Poly(Glu:Tyr)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50510133(CHEMBL4446681)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-His6-fused SRC (M1 to L536 residues) expressed in Sf9 insect cells using Poly(Glu:Tyr)4:1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591527(CHEMBL5171972)
Affinity DataIC50:  9.02E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50510133(CHEMBL4446681)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused EGFR C-terminal domain (H672 to A1210) expressed in Sf9 insect cells using Poly(G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591521(CHEMBL5190558)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591523(CHEMBL5192930)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591528(CHEMBL5207672)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591530(CHEMBL5174746)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591537(CHEMBL5197906)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591538(CHEMBL5205807)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591540(CHEMBL5204046)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591541(CHEMBL5197863)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591521(CHEMBL5190558)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591542(CHEMBL5173787)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591543(CHEMBL5184139)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591544(CHEMBL5185283)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591545(CHEMBL5184604)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Federico Ii Of Naples

Curated by ChEMBL
LigandPNGBDBM50591546(CHEMBL5193098)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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