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Found 47 with Last Name = 'hanus' and Initial = 'j'
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132192(CHEMBL102871 | N*2*-(4-Amino-cyclohexyl)-N*6*-(3-c...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  450nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM7585((R,S)-Roscovitine | 2,6,9-Trisubstituted purine de...)
Affinity DataIC50:  650nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056163((S)-2-(6-(benzylamino)-9-isopropyl-9H-purin-2-ylam...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056169(1-(6-Benzylamino-9-isopropyl-9H-purin-2-ylamino)-p...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM10636(2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056159(2-[6-(Cyclohexyl-methyl-amino)-9-methyl-9H-purin-2...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132199(3-{[8-Chloro-2-(1-hydroxymethyl-propylamino)-9-iso...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056177(2-[6-Benzylamino-2-(2-hydroxy-ethylamino)-purin-9-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132196(2-(6-Benzylamino-9-isopropyl-8-methyl-9H-purin-2-y...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132197(2-(6-Benzylamino-9-isopropyl-8-mercapto-9H-purin-2...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056174(Benzyl-(2-chloro-9-methyl-9H-purin-6-yl)-amine | C...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132193(2-[8-Chloro-6-(3-chloro-phenylamino)-9-isopropyl-9...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132198(CHEMBL103567 | N*2*-(4-Amino-cyclohexyl)-N*6*-(3-c...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132189(2-(6-Benzylamino-9-isopropyl-8-nitro-9H-purin-2-yl...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056168(Benzyl-(2-chloro-9-isopropyl-9H-purin-6-yl)-amine ...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132190(2-(6-Benzylamino-8-chloro-9-isopropyl-9H-purin-2-y...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056164(2-(6-Benzylamino-9H-purin-2-ylamino)-ethanol | CHE...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056170(CHEMBL337454 | N*6*-Benzyl-9-methyl-9H-purine-2,6-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056176((2-Chloro-9-methyl-9H-purin-6-yl)-(3-methyl-but-2-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056160(Benzyl-(9-methyl-9H-purin-6-yl)-amine | CHEMBL1310...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056172(2-(6-Amino-9-methyl-9H-purin-2-ylamino)-ethanol | ...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132195(6-Benzylamino-2-(1-hydroxymethyl-propylamino)-9-is...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056165(2-[9-Methyl-6-(3-methyl-but-2-enylamino)-9H-purin-...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132188(2-(8-Amino-6-benzylamino-9-isopropyl-9H-purin-2-yl...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50009702(2-Chloro-9-methyl-9H-purin-6-ylamine | CHEMBL31739...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056167(CHEMBL133214 | N*6*-Benzyl-9H-purine-2,6-diamine)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132191(2-(6-Benzylamino-8-bromo-9-isopropyl-9H-purin-2-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50208879(2,6-diaminopurine | 9H-Purine-2,6-diamine0.5M H2SO...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of purified Cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis (precipitation at the higher concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132194(2-[6-Benzylamino-8-(3-hydroxy-propylamino)-9-isopr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132200(2-(6-Benzylamino-9-isopropyl-8-propoxy-9H-purin-2-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056173((2-Chloro-9-methyl-9H-purin-6-yl)-cyclohexyl-methy...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM33218(Adenine, 1 | CHEMBL226345 | purine, 6)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056161(2-(6-Amino-9H-purin-2-ylamino)-ethanol | CHEMBL130...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50205363(6-(benzylamino)purine | 6-BAP | 6-[(phenylmethyl)a...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056162(Benzyl-(3-methyl-3,9-dihydro-2H-purin-6-yl)-amine ...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50030961(2-Methyl-9H-purin-6-ylamine | CHEMBL330897)
Affinity DataIC50:  3.20E+5nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50009685(9-METHYL-9H-PURIN-6-AMINE | 9-Methyl-9H-adenine | ...)
Affinity DataIC50: >3.50E+5nMAssay Description:Inhibition of purified Cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis (precipitation at the higher concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056171(3-Methyl-3,9-dihydro-2H-purin-6-ylamine | CHEMBL13...)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056175(7-Methyl-8,9-dihydro-7H-purin-6-ylamine | CHEMBL33...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056181(Benzyl-(1-methyl-6,9-dihydro-1H-purin-6-yl)-amine ...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056180(2-Chloro-9H-purin-6-ylamine | CHEMBL134192 | EN300...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of purified Cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis (precipitation at the higher concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056179(Benzyl-(7-methyl-8,9-dihydro-7H-purin-6-yl)-amine ...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50056166(1-Methyl-6,9-dihydro-1H-purin-6-ylamine | 1-Methyl...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed