TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human His6-tagged PDE4D2 expressed in baculovirus infected Sf9 insect cells using cAMP as substrate preincubated for 5 to 1...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 127nMAssay Description:Inhibition of recombinant human His6-tagged PDE4D2 expressed in baculovirus infected Sf9 insect cells using cAMP as substrate preincubated for 5 to 1...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 128nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 137nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 166nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 225nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 241nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 288nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 293nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 356nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 431nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 562nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 584nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 637nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair