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Found 52 with Last Name = 'kritzer' and Initial = 'ja'
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50565476(CHEMBL4780117)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells by catalytic enzyme-linked click chemistry assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50: <10nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50565475(CHEMBL4777401)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells by catalytic enzyme-linked click chemistry assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50525088(CHEMBL4461497)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells by catalytic enzyme-linked click chemistry assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  282nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50559890(CHEMBL4757551)
Affinity DataIC50:  410nMAssay Description:Displacement of fluorescent pTyr from recombinant His6-tagged human STAT3 (codons 127-711) expressed in Escherichia coli BL21 Rosetta after 45 mins b...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50559892(CHEMBL4748862)
Affinity DataIC50:  610nMAssay Description:Displacement of fluorescent pTyr from recombinant His6-tagged human STAT3 (codons 127-711) expressed in Escherichia coli BL21 Rosetta after 45 mins b...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048520(CHEMBL3360777)
Affinity DataIC50:  730nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048520(CHEMBL3360777)
Affinity DataIC50:  4.11E+3nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50559891(CHEMBL4739963)
Affinity DataIC50:  7.10E+3nMAssay Description:Displacement of fluorescent pTyr from recombinant His6-tagged human STAT3 (codons 127-711) expressed in Escherichia coli BL21 Rosetta after 45 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048519(CHEMBL3360776)
Affinity DataIC50:  8.43E+3nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048498(CHEMBL3360774)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048494(CHEMBL3360770)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048490(Coumermycin A1)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048494(CHEMBL3360770)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048499(CHEMBL3360775)
Affinity DataIC50:  1.68E+4nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048492(CHEMBL3360767)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048493(CHEMBL3360769)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048519(CHEMBL3360776)
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEH domain-containing protein 1(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453873(CHEMBL4210179)
Affinity DataIC50:  2.71E+4nMAssay Description:Inhibition of fluorescence-labelled cNPF1 probe binding to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells pretrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048490(Coumermycin A1)
Affinity DataIC50:  2.81E+4nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048499(CHEMBL3360775)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEH domain-containing protein 1(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453871(CHEMBL4203846)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of fluorescence-labelled cNPF1 probe binding to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells pretrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048497(CHEMBL3360773)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048493(CHEMBL3360769)
Affinity DataIC50:  3.79E+4nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048498(CHEMBL3360774)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEH domain-containing protein 1(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453874(CHEMBL4218026)
Affinity DataIC50:  3.89E+4nMAssay Description:Inhibition of fluorescence-labelled cNPF1 probe binding to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells pretrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEH domain-containing protein 1(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453868(CHEMBL4214569)
Affinity DataIC50:  5.55E+4nMAssay Description:Inhibition of fluorescence-labelled cNPF1 probe binding to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells pretrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEH domain-containing protein 1(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453867(CHEMBL4205818)
Affinity DataIC50:  6.28E+4nMAssay Description:Inhibition of fluorescence-labelled cNPF1 probe binding to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells pretrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048496(CHEMBL3360772)
Affinity DataIC50: >6.70E+4nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEH domain-containing protein 1(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453869(CHEMBL4215110)
Affinity DataIC50:  6.88E+4nMAssay Description:Inhibition of fluorescence-labelled cNPF1 probe binding to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells pretrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEH domain-containing protein 1(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453866(CHEMBL4210684)
Affinity DataIC50:  7.65E+4nMAssay Description:Inhibition of fluorescence-labelled cNPF1 probe binding to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells pretrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEH domain-containing protein 1(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453872(CHEMBL4209370)
Affinity DataIC50:  8.81E+4nMAssay Description:Inhibition of fluorescence-labelled cNPF1 probe binding to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells pretrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048492(CHEMBL3360767)
Affinity DataIC50:  9.45E+4nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor substrate 15(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453870(CHEMBL4215523)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity to GST-fused Eps15 EH2 domain (unknown origin) expressed in Escherichia coli BL21 cells under high salt condition by fluorescence po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048495(CHEMBL3360771)
Affinity DataIC50: >1.20E+5nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048497(CHEMBL3360773)
Affinity DataIC50:  1.21E+5nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048496(CHEMBL3360772)
Affinity DataIC50:  1.37E+5nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048491(CHEMBL3360762)
Affinity DataIC50: >1.60E+5nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048495(CHEMBL3360771)
Affinity DataIC50:  1.68E+5nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Tufts University

Curated by ChEMBL
LigandPNGBDBM50423645(Albamycin | Cathomycin | NOVOBIOCIN)
Affinity DataIC50:  2.31E+5nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50048491(CHEMBL3360762)
Affinity DataIC50:  2.33E+5nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90(Oryctolagus cuniculus)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50423645(Albamycin | Cathomycin | NOVOBIOCIN)
Affinity DataIC50:  4.14E+5nMAssay Description:Inhibition of HSP90 in rabbit reticulocyte lysate after 90 mins by luciferase renaturation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50565476(CHEMBL4780117)
Affinity DataKon:  0.00690M-1s-1Assay Description:Binding affinity to recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by surface ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50525088(CHEMBL4461497)
Affinity DataKd:  17nMAssay Description:Binding affinity to recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells assessed as binding constant by surface plasm...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50565475(CHEMBL4777401)
Affinity DataKd:  7.20nMAssay Description:Binding affinity to recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells assessed as binding constant by surface plasm...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50565475(CHEMBL4777401)
Affinity DataKon:  0.00420M-1s-1Assay Description:Binding affinity to recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by surface ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50525088(CHEMBL4461497)
Affinity DataKon:  0.0110M-1s-1Assay Description:Binding affinity to recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by surface ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEH domain-containing protein 1(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453870(CHEMBL4215523)
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells measured after 1 hr in presence of 15 mM NaCl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEH domain-containing protein 1(Homo sapiens)
Tufts University

Curated by ChEMBL
LigandPNGBDBM50453870(CHEMBL4215523)
Affinity DataKd:  1.51E+4nMAssay Description:Binding affinity to GST-fused EHD1 EH domain (unknown origin) expressed in Escherichia coli BL21 cells measured after 1 hr in presence of 150 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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