TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 84nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 96nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 96nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 105nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 108nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 188nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 322nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 405nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 455nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 503nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 523nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 540nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 550nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 570nMAssay Description:Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 677nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 684nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 710nMAssay Description:Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 900nMAssay Description:Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 995nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.16E+3nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair