Affinity DataKi: 2.10nMAssay Description:Inhibition of DPP4 in rat plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV calculated from IC50 from standard dose inhibition curve using cheng-Prussoff equation; range=61+/...More data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
Affinity DataKi: 109nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
Affinity DataKi: 117nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
Affinity DataKi: 121nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
Affinity DataKi: 128nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
Affinity DataKi: 504nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
Affinity DataKi: 1.27E+3nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
Affinity DataKi: 3.35E+3nMAssay Description:Inhibitory constant against Dipeptidylpeptidase IV activityMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of DPP3More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: >3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.63nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair