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Found 589 with Last Name = 'ehlert' and Initial = 'je'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304196(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Affinity DataIC50:  2nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304196(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Affinity DataIC50:  5nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512623(CHEMBL4582775)
Affinity DataIC50:  6nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512644(CHEMBL4467219)
Affinity DataIC50:  9nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304197(CHEMBL593987 | N-(4-(benzo[d]thiazol-2-yl)-3-fluor...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304197(CHEMBL593987 | N-(4-(benzo[d]thiazol-2-yl)-3-fluor...)
Affinity DataIC50:  9nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512620(CHEMBL4461224)
Affinity DataIC50:  9nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308196(2-(3-Chloro-4-hydroxyanilino)-9-methoxy-5,7-dihydr...)
Affinity DataIC50:  11nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  11nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512624(CHEMBL4568910)
Affinity DataIC50:  11nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50304207(CHEMBL595615 | N-(4-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512645(CHEMBL4532743)
Affinity DataIC50:  12nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512662(CHEMBL4464846)
Affinity DataIC50:  12nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)
Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512623(CHEMBL4582775)
Affinity DataIC50:  14nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(CHEMBL595615 | N-(4-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304220(CHEMBL593911 | N-[4-(Benzo[d]thiazol-2''-yl)-3-met...)
Affinity DataIC50:  15nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308194(2-(3-Hydroxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...)
Affinity DataIC50:  15nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512620(CHEMBL4461224)
Affinity DataIC50:  15nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304198(CHEMBL593274 | N-(4-(benzo[d]thiazol-2-yl)-3-chlor...)
Affinity DataIC50:  16nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512643(CHEMBL4460703)
Affinity DataIC50:  16nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308195(2-(3-Hydroxy-4-methoxyanilino)-9-methoxy-5,7-dihyd...)
Affinity DataIC50:  18nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512660(CHEMBL4560792)
Affinity DataIC50:  19nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512635(CHEMBL4435107)
Affinity DataIC50:  19nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512668(CHEMBL4452780)
Affinity DataIC50:  19nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512644(CHEMBL4467219)
Affinity DataIC50:  21nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50300041(7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...)
Affinity DataIC50:  23nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304200(CHEMBL596292 | N-[4-(6''-Chlorobenzo[d]thiazol-2''...)
Affinity DataIC50:  24nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)
Affinity DataIC50:  26nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304199(CHEMBL604992 | N-[4-(6''-Methoxybenzo[d]thiazol-2'...)
Affinity DataIC50:  26nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)
Affinity DataIC50:  26nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512634(CHEMBL4552592)
Affinity DataIC50:  27nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304197(CHEMBL593987 | N-(4-(benzo[d]thiazol-2-yl)-3-fluor...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304198(CHEMBL593274 | N-(4-(benzo[d]thiazol-2-yl)-3-chlor...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)
Affinity DataIC50:  28nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308191(2-(4-Hydroxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...)
Affinity DataIC50:  28nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)
Affinity DataIC50:  29nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512662(CHEMBL4464846)
Affinity DataIC50:  30nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512668(CHEMBL4452780)
Affinity DataIC50:  32nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304211(CHEMBL596087 | N-[4-(Benzo[d]thiazol-2''-yl)-2-flu...)
Affinity DataIC50:  32nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304211(CHEMBL596087 | N-[4-(Benzo[d]thiazol-2''-yl)-2-flu...)
Affinity DataIC50:  32nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)
Affinity DataIC50:  34nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512640(CHEMBL4555461)
Affinity DataIC50:  35nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308189(2-(3-Chloro-4-hydroxyanilino)-5,7-dihydro-6H-pyrim...)
Affinity DataIC50:  35nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304198(CHEMBL593274 | N-(4-(benzo[d]thiazol-2-yl)-3-chlor...)
Affinity DataIC50:  37nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304208(CHEMBL595406 | N-(4-(benzo[d]thiazol-2-yl)-2-methy...)
Affinity DataIC50:  38nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304198(CHEMBL593274 | N-(4-(benzo[d]thiazol-2-yl)-3-chlor...)
Affinity DataIC50:  38nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304199(CHEMBL604992 | N-[4-(6''-Methoxybenzo[d]thiazol-2'...)
Affinity DataIC50:  41nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50512661(CHEMBL4438513)
Affinity DataIC50:  41nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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