TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant Nav 1.8 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human Nav1.8 channel expressed in human HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human Nav1.8 channel expressed in HEK293 cells at -40 mV by patch clamp methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of mouse NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: <30nMAssay Description:Inhibition of mouse NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: <30nMAssay Description:Inhibition of mouse NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant Nav1.8 channel expressed in HEK293 cells by whole cell voltage clamp techniqueMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of mouse NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair