TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.0617nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.0820nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.123nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.155nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.155nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.162nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.224nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.234nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.302nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.316nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.316nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.355nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.389nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.513nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.562nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.661nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.676nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.676nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.851nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.871nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 1.87nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of Dipeptidyl Peptidase IVMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of PKD2 ( assessed as residual activity at 1 uM ) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Competitive inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min ...More data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by spectrop...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of human uPA using S-2444 as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in human; Moderately activeMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrate preincubate...More data for this Ligand-Target Pair