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Found 69 with Last Name = 'kodama' and Initial = 'k'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089825(1-[4-(3-Chloro-4-methoxy-benzylamino)-6-nitro-phth...)
Affinity DataIC50:  0.300nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089837(4-(3-Chloro-4-methoxy-benzylamino)-1-thiomorpholin...)
Affinity DataIC50:  0.320nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089826(1-[4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-phth...)
Affinity DataIC50:  0.5nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089807(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-oxo-piperi...)
Affinity DataIC50:  0.530nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089833(4-(3-Chloro-4-methoxy-benzylamino)-1-piperidin-1-y...)
Affinity DataIC50:  0.550nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089814(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-hydroxy-pi...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of phosphodiesterase 5 (PDE5) from porcine platelets, range 0.442-0.710More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50369544(CHEMBL545012)
Affinity DataIC50:  0.700nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089827(4-(3-Chloro-4-methoxy-benzylamino)-1-[4-(2-hydroxy...)
Affinity DataIC50:  0.700nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089821(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-hydroxy-4-...)
Affinity DataIC50:  0.700nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089815(1-[4-(3-Chloro-4-methoxy-benzylamino)-6-trifluorom...)
Affinity DataIC50:  0.730nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089841(4-(3-Chloro-4-methoxy-benzylamino)-1-(1,1-dioxo-1l...)
Affinity DataIC50:  0.790nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089832(1-[6,7-Dichloro-4-(3-chloro-4-methoxy-benzylamino)...)
Affinity DataIC50:  0.860nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089820(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-hydroxymet...)
Affinity DataIC50:  0.930nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089830(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-methyl-pip...)
Affinity DataIC50:  0.950nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089816(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-methoxy-pi...)
Affinity DataIC50:  1.10nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089809(4-(3-Chloro-4-methoxy-benzylamino)-1-piperazin-1-y...)
Affinity DataIC50:  1.20nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089838(4-(3-Chloro-4-methoxy-benzylamino)-1-(3-hydroxy-pi...)
Affinity DataIC50:  1.20nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089842(4-(3-Chloro-4-methoxy-benzylamino)-1-imidazol-1-yl...)
Affinity DataIC50:  1.5nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089818(4-(3-Chloro-4-methoxy-benzylamino)-1-[4-(2-hydroxy...)
Affinity DataIC50:  1.70nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089812(4-(3-Chloro-4-methoxy-benzylamino)-1-(3,6-dihydro-...)
Affinity DataIC50:  1.90nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089836(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-hydroxy-pi...)
Affinity DataIC50:  2nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  2.20nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089817(4-(3-Chloro-4-methoxy-benzylamino)-1-(3-hydroxy-pr...)
Affinity DataIC50:  2.60nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089823(4-(3-Chloro-4-methoxy-benzylamino)-1-[(pyridin-2-y...)
Affinity DataIC50:  2.70nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066450(1-Chloro-4-(3-chloro-4-methoxy-benzylamino)-phthal...)
Affinity DataIC50:  3nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089839(1-[4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-phth...)
Affinity DataIC50:  3.10nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066451((3-Chloro-4-methoxy-benzyl)-(4-chloro-7-nitro-phth...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066454(CHEMBL25616 | Sodium; 1-{4-[(benzo[1,3]dioxol-5-yl...)
Affinity DataIC50:  3.70nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089808(1-[6-Chloro-4-(3-chloro-4-methoxy-benzylamino)-pht...)
Affinity DataIC50:  4.40nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066450(1-Chloro-4-(3-chloro-4-methoxy-benzylamino)-phthal...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066448((3-Chloro-4-methoxy-benzyl)-(4-chloro-7-trifluorom...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089834(4-(3-Chloro-4-methoxy-benzylamino)-1-[(pyridin-4-y...)
Affinity DataIC50:  6.70nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089822(4-(3-Chloro-4-methoxy-benzylamino)-1-[(pyridin-3-y...)
Affinity DataIC50:  6.80nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066454(CHEMBL25616 | Sodium; 1-{4-[(benzo[1,3]dioxol-5-yl...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089811(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-pyridin-2-...)
Affinity DataIC50:  11nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089810(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-hydroxy-cy...)
Affinity DataIC50:  12nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089819(CHEMBL544540 | N-{1-[4-(3-Chloro-4-methoxy-benzyla...)
Affinity DataIC50:  14nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089840(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-pyrimidin-...)
Affinity DataIC50:  19nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066447(1-Chloro-4-(3-chloro-4-ethoxy-benzylamino)-phthala...)
Affinity DataIC50:  49nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066452((3-Chloro-4-methoxy-benzyl)-(4,7-dichloro-phthalaz...)
Affinity DataIC50:  54nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066449(Benzo[1,3]dioxol-5-ylmethyl-(4-chloro-7-nitro-phth...)
Affinity DataIC50:  63nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066457(1-Chloro-4-[1-(3-chloro-4-methoxy-phenyl)-ethylami...)
Affinity DataIC50:  98nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066446(4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-1-chloro-p...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066445(4-Chloro-1-(3-chloro-4-methoxy-benzylamino)-phthal...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066456(1-Chloro-4-(4-methoxy-benzylamino)-phthalazine-6-c...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089829(1,4-Bis-(3-chloro-4-methoxy-benzylamino)-phthalazi...)
Affinity DataIC50:  150nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM23620(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin...)
Affinity DataIC50:  574nMAssay Description:Inhibition of phosphodiesterase 5 (PDE5) from porcine platelets, range 0.244-1.35More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50089835(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-hydroxy-pi...)
Affinity DataIC50:  600nMAssay Description:50% inhibitory concentration against phosphodiesterase 5 (PDE5) from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50066455((3-Chloro-4-methoxy-benzyl)-(4,6-dichloro-phthalaz...)
Affinity DataIC50:  810nMAssay Description:Inhibition of Phosphodiesterase 5 from porcine plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Sus scrofa)
Eisai

Curated by ChEMBL
LigandPNGBDBM15296(6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...)
Affinity DataIC50:  843nMAssay Description:Inhibition of phosphodiesterase 3 (PDE3) from porcine platelets, range 0.581-1.23More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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