TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 0.130nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 0.370nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 1nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 1.5nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 1.90nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 2nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 2.20nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of PAC3 homodimer (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 50nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 55nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 60nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 65nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 120nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 130nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 174nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of PAC3 homodimerization by protein fragment complementation assayMore data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 370nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 1.10E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer TS by primer extension assayMore data for this Ligand-Target Pair
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 1.20E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer TS by primer extension assayMore data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 2.30E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 2.90E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center
National Institutes of Health, National Institutes of Health Biomedical Research Center
Affinity DataIC50: 4.90E+3nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer TS by primer extension assayMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human Tdp1 using 3'-phosphate-(4-methylumbelliferone)-thymidine as substrate after 180 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of human HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Biomedicinal Information Research Center (Birc)
Curated by ChEMBL
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of human HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of PAC3 homodimer (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
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