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Found 30 with Last Name = 'ishibashi' and Initial = 'm'
TargetNeurogenic locus notch homolog protein 1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50465465(Anvirzel | NSC-692219 | Oleandrin)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50277171(Asclepin | CHEBI:2867)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50277174(CHEMBL4164399)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50277175(Uscharin)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50277169(CHEMBL4166735)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50277173(CHEBI:3329 | Calotropin)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50240897(2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50277170(CHEMBL360322)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50240943(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7-methoxy-chrom...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50277172(CHEBI:9913 | Uscharidin)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50465463(CHEMBL4292704)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50465464(CHEMBL4282921)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50465467(CHEMBL229258)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50090908(CHEBI:67291 | CHEMBL1774404)
Affinity DataIC50:  3.00E+3nMAssay Description:Activation of GSK-3beta in HEK293 cells assessed as suppression of TCF/beta-catenin transcriptional activity after 24 hrs by SuperTOPFlash reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor HES-1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50378454(LINDBLADIONE)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of Cy3-labeled mouse recombinant Hes1 (3-281) dimer formation expressed in Escherichia coli by microplate-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50465466(CHEMBL229259)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor HES-1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50378456(LYCOGALIC ACID A | LYCOGARIC ACID A)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Cy3-labeled mouse recombinant Hes1 (3-281) dimer formation expressed in Escherichia coli by microplate-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50090907(CHEBI:66041 | CHEMBL444160)
Affinity DataIC50:  6.80E+3nMAssay Description:Activation of GSK-3beta in HEK293 cells assessed as suppression of TCF/beta-catenin transcriptional activity after 24 hrs by SuperTOPFlash reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor HES-1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50378457(CHEMBL572017)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of Cy3-labeled mouse recombinant Hes1 (3-281) dimer formation expressed in Escherichia coli by microplate-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor HES-1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50378459(NUDIPOSIDE)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of Cy3-labeled mouse recombinant Hes1 (3-281) dimer formation expressed in Escherichia coli by microplate-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50090909(CHEMBL3120496)
Affinity DataIC50:  1.16E+4nMAssay Description:Activation of GSK-3beta in HEK293 cells assessed as suppression of TCF/beta-catenin transcriptional activity after 24 hrs by SuperTOPFlash reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor HES-1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50378455(LYCOGARUBIN B)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of Cy3-labeled mouse recombinant Hes1 (3-281) dimer formation expressed in Escherichia coli by microplate-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50277176(CHEMBL4176111)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM23208((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50249140(CHEMBL470503 | colubrinic acid)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50249188(Alphitolic acid | CHEMBL511805)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor HES-1(Mus musculus)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50378458(LYONISIDE)
Affinity DataIC50:  4.81E+4nMAssay Description:Inhibition of Cy3-labeled mouse recombinant Hes1 (3-281) dimer formation expressed in Escherichia coli by microplate-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50274058(CHEMBL522108 | ceanothanolic acid)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50377959(CHEMBL491069)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed