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Found 71 with Last Name = 'taylor' and Initial = 'mc'
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50:  0.610nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50108994(CHEMBL3600555)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50108990(CHEMBL3600551)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50108991(CHEMBL3600552)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50108995(CHEMBL3600556)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50108992(CHEMBL3600553)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194809(CHEMBL3910753)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50108993(CHEMBL3600554)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484769(CHEMBL1958429)
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194801(CHEMBL3910120)
Affinity DataIC50:  11nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194800(CHEMBL3890983)
Affinity DataIC50:  12nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484758(CHEMBL1958439)
Affinity DataIC50:  13nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194807(CHEMBL3985938)
Affinity DataIC50:  13nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50435291(CHEMBL2393095)
Affinity DataIC50:  15nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM9427(CHEMBL1083790 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  16nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194803(CHEMBL3906380)
Affinity DataIC50:  16nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194798(CHEMBL3901071)
Affinity DataIC50:  16nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194806(CHEMBL3937637)
Affinity DataIC50:  17nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036283(CHEMBL3353041)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194799(CHEMBL3972196)
Affinity DataIC50:  20nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484757(CHEMBL1958436)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484764(CHEMBL453755)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484756(CHEMBL1958434)
Affinity DataIC50:  22nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484755(CHEMBL1958437)
Affinity DataIC50:  22nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484761(CHEMBL1958433)
Affinity DataIC50:  22nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484762(CHEMBL272847)
Affinity DataIC50:  23nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM9425(CHEMBL1083789 | Heterodimeric Tacrine-Based Inhibi...)
Affinity DataIC50:  24nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194808(CHEMBL3902953)
Affinity DataIC50:  24nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194793(CHEMBL3977576)
Affinity DataIC50:  24nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50:  26nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194796(CHEMBL3941365)
Affinity DataIC50:  27nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484770(CHEMBL1958430)
Affinity DataIC50:  28nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484765(CHEMBL1955942)
Affinity DataIC50:  29nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194790(CHEMBL3970941)
Affinity DataIC50:  31nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194795(CHEMBL3945505)
Affinity DataIC50:  31nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194791(CHEMBL3905154)
Affinity DataIC50:  35nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194797(CHEMBL3939732)
Affinity DataIC50:  36nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484760(CHEMBL1958438)
Affinity DataIC50:  42nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194804(CHEMBL3981921)
Affinity DataIC50:  45nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194792(CHEMBL3973917)
Affinity DataIC50:  46nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484768(CHEMBL1958440)
Affinity DataIC50:  48nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194802(CHEMBL3908171)
Affinity DataIC50:  48nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194805(CHEMBL3909021)
Affinity DataIC50:  54nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484750(CHEMBL1958428)
Affinity DataIC50:  68nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036282(CHEMBL3353040)
Affinity DataIC50:  73nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484751(CHEMBL1958422)
Affinity DataIC50:  84nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484767(CHEMBL1958424)
Affinity DataIC50:  123nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484763(CHEMBL1958432)
Affinity DataIC50:  132nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
London School of Hygiene and Tropical Medicine

Curated by ChEMBL
LigandPNGBDBM50484759(CHEMBL1958423)
Affinity DataIC50:  149nMAssay Description:Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50194794(CHEMBL3981794)
Affinity DataIC50:  158nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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