Affinity DataIC50: 4.30nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Agonist activity at PGI2 in human platelet-rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Lucknow
Curated by ChEMBL
University Of Lucknow
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Lucknow
Curated by ChEMBL
University Of Lucknow
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Lucknow
Curated by ChEMBL
University Of Lucknow
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Lucknow
Curated by ChEMBL
University Of Lucknow
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Lucknow
Curated by ChEMBL
University Of Lucknow
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
Affinity DataIC50: 2.91E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of recombinant ovine COX1 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of recombinant ovine COX1 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassayMore data for this Ligand-Target Pair