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Found 16 with Last Name = 'khan' and Initial = 'mf'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50510873(CHEMBL4436337)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50095203(CHEMBL94751 | [(S)-6-(3-Benzhydryl-6-oxo-6H-pyrida...)
Affinity DataIC50:  81nMAssay Description:Agonist activity at PGI2 in human platelet-rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Lucknow

Curated by ChEMBL
LigandPNGBDBM50155759(CHEMBL3781453)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Lucknow

Curated by ChEMBL
LigandPNGBDBM50155760(CHEMBL3780639)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Lucknow

Curated by ChEMBL
LigandPNGBDBM50155761(CHEMBL3782051)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Lucknow

Curated by ChEMBL
LigandPNGBDBM50155762(CHEMBL3781672)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Lucknow

Curated by ChEMBL
LigandPNGBDBM50155758(Imbricatolic Acid)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50191201(CHEMBL3978955)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50191273(CHEMBL3908604)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50340427(1-((3S,8S,9S,10R,13S,14S,17R)-16-(benzylamino)-3-h...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50340428(3-(3,4-dimethoxyphenyl)-1-((3S,8R,9S,10R,13S,14S)-...)
Affinity DataIC50:  2.62E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50340430((2S,4aR,4bS,6aS,9R,11aS,11bS)-2-Hydroxy-9-(4-isopr...)
Affinity DataIC50:  2.91E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50340429((2S,4aR,4bS,6aS,9R,11aS,11bS)-2-Hydroxy-9-(4-metho...)
Affinity DataIC50:  3.27E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50340426(16-Dehydropregnenolone acetate | CHEMBL1761683)
Affinity DataIC50:  3.56E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50191273(CHEMBL3908604)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of recombinant ovine COX1 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50191201(CHEMBL3978955)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of recombinant ovine COX1 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed