Affinity DataIC50: 0.740nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 0.930nMAssay Description:Inhibition of wild type human N-terminal GST-fusion tagged TRKB kinase domain (456 to 822 residues) expressed in baculovirus expression system by HTR...More data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 0.970nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compound was measured for inhibition of collagenolytic of human Cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Compound was measured for inhibition of collagenolytic of human Cathepsin LMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of wild type human His-tagged TRKA kinase domain (441 to 796 residues) expressed in baculovirus expression system by HTRF assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of juxtamembrane region deficient recombinant human N-terminal His6-tagged/GST-tagged TrkA (498 to 796 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of TRKA E735A mutant (unknown origin) expressed in baculovirus infected sf9 cells assessed as kinase domain dimerization by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of juxtamembrane region containing recombinant human N-terminal His6-tagged/GST-tagged TrkA (473 to 796 residues) expressed in baculovirus...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human ACC2 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human ACC2 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human ACC2 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of juxtamembrane region containing recombinant human N-terminal His6-tagged/GST-tagged TrkA (473 to 796 residues) expressed in baculovirus...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human ACC2 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human TrkB expressed in DHFR deficient CHO cells assessed as inhibition of human brain-derived neurotrophic factor-induced ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant human TrkC expressed in DHFR deficient CHO cells assessed as inhibition of human neurotrophin-3-induced calcium influx by F...More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human ACC2 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human ACC2 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human ACC2 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of juxtamembrane region deficient recombinant human N-terminal His6-tagged/GST-tagged TrkA (498 to 796 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 9.90nMAssay Description:Inhibition of recombinant human TrkA expressed in DHFR deficient CHO cells assessed as inhibition of human beta-nerve growth factor-induced calcium i...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human ACC2 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human ACC1 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human ACC1 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human ACC1 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair