TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.610nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.830nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.870nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibitory constant against Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 34.1nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 41.5nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 175nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 194nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beckman Research Institute
Curated by ChEMBL
Beckman Research Institute
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant GST-tagged c-Src (unknown origin) expressed in insect cells using pEY as substrate preincubated with enzyme followed by [33...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 468nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University
Curated by ChEMBL
Friedrich-Schiller-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-LO in fMLP-stimulated human monocytes assessed as reduction in HETE formationMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair