Affinity DataKi: 0.280nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -53.6kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -53.1kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
B.V. Patel Pharmaceutical Education and Research Development
Curated by ChEMBL
B.V. Patel Pharmaceutical Education and Research Development
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.960nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -51.4kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
TargetAdenosine receptor A2b(Homo sapiens (Human))
B.V. Patel Pharmaceutical Education and Research Development
Curated by ChEMBL
B.V. Patel Pharmaceutical Education and Research Development
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Binding affinity to human CA2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity to rabbit factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Binding affinity to human CA2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.9kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Binding affinity to human CA2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Binding affinity to human CA2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Binding affinity to human CA2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Competitive inhibition of PNP in human DoHH2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Binding affinity to human CA2 assessed as inhibition constantMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
B.V. Patel Pharmaceutical Education and Research Development
Curated by ChEMBL
B.V. Patel Pharmaceutical Education and Research Development
Curated by ChEMBL
Affinity DataKi: 6.70nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Competitive inhibition of human recombinant PNP using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 8.80nMAssay Description:Binding affinity to human CA2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
B.V. Patel Pharmaceutical Education and Research Development
Curated by ChEMBL
B.V. Patel Pharmaceutical Education and Research Development
Curated by ChEMBL
Affinity DataKi: 9.40nMAssay Description:Displacement of [3H]HEMADO from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human MINO cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human K562 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human Jurkat cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human PBMC using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Competitive inhibition of PNP in human MC116 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Competitive inhibition of PNP in human SU-DHL-1 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity to human CA2 assessed as inhibition constantMore data for this Ligand-Target Pair