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Found 52 with Last Name = 'huby' and Initial = 'nj'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  0.121nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  0.394nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041304(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041294(1-(3-Biphenyl-4-yl-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041300(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  21nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041298(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  26nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041303(1-[3-(4-Isopropyl-phenyl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataKi:  36nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041307(1-[3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1...)
Affinity DataKi:  78nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041299(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataKi:  122nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041296(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataKi:  131nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041296(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataKi:  131nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041306(1-[3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  630nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041295(1-[3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  857nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041297(1-(8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]oct-2-yl)...)
Affinity DataKi:  1.01E+3nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041302(1-(8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]oct-2-yl)...)
Affinity DataKi:  1.36E+3nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041310(1-[3-(4-tert-Butyl-phenyl)-8-methyl-8-aza-bicyclo[...)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041305(1-(8-Methyl-3-o-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041309(1-(3-Ethyl-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl)-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041301(1-(3-Cyclohexyl-8-methyl-8-aza-bicyclo[3.2.1]oct-2...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50:  0.0430nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50:  0.115nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041304(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041294(1-(3-Biphenyl-4-yl-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041300(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041296(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041296(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041299(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041298(1-(8-Methyl-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041306(1-[3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2....)
Affinity DataIC50:  15nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041297(1-(8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]oct-2-yl)...)
Affinity DataIC50:  48nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041295(1-[3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2....)
Affinity DataIC50:  71nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041302(1-(8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]oct-2-yl)...)
Affinity DataIC50:  114nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041307(1-[3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1...)
Affinity DataIC50:  152nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235155(US9359345, 1)
Affinity DataIC50:  254nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041303(1-[3-(4-Isopropyl-phenyl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataIC50:  436nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235161(US9359345, 7)
Affinity DataIC50:  470nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235157(US9359345, 3)
Affinity DataIC50:  1.21E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041305(1-(8-Methyl-3-o-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235163(US9359345, 9)
Affinity DataIC50:  1.61E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235158(US9359345, 4)
Affinity DataIC50:  1.73E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041310(1-[3-(4-tert-Butyl-phenyl)-8-methyl-8-aza-bicyclo[...)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041301(1-(3-Cyclohexyl-8-methyl-8-aza-bicyclo[3.2.1]oct-2...)
Affinity DataIC50:  4.61E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235162(US9359345, 8)
Affinity DataIC50:  5.07E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235165(US9359345, 11)
Affinity DataIC50:  5.37E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235164(US9359345, 10)
Affinity DataIC50:  5.80E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235166(US9359345, 12)
Affinity DataIC50:  6.03E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235159(US9359345, 5)
Affinity DataIC50:  6.24E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235160(US9359345, 6)
Affinity DataIC50:  7.51E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM235156(US9359345, 2)
Affinity DataIC50:  7.74E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50041309(1-(3-Ethyl-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl)-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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